Non-ergodicity correction in laser speckle biomedical imaging

P. Zakharov; A. C. Völker; F. Buck; B. Weber; F. Scheffold

doi:10.1117/12.727646

18 July 2007 Non-ergodicity correction in laser speckle biomedical imaging

P. Zakharov, A. C. Völker, F. Buck, B. Weber, F. Scheffold

Proceedings Volume 6631, Novel Optical Instrumentation for Biomedical Applications III; 66310D (2007) https://doi.org/10.1117/12.727646
Event: European Conferences on Biomedical Optics, 2007, Munich, Germany

Abstract

We discuss a new approach to laser speckle biomedical imaging with the goal to establish a quantitative link between the measured signal and the local dynamic properties of Brownian motion or blood flow. We demonstrate that the presence of a static component in laser speckle imaging signal can significantly complicate the quantitative interpretation of the imaging data. With Monte-Carlo simulations and model experiments we show that the error in the mean particles velocity extracted using traditional approaches can reach several orders of magnitude. With a proper data treatment on the other side the error can be substantially reduced. We suggest a simple data processing scheme that properly accounts for a static component in the scattered light intensity.

Citation Download Citation

P. Zakharov, A. C. Völker, F. Buck, B. Weber, and F. Scheffold "Non-ergodicity correction in laser speckle biomedical imaging", Proc. SPIE 6631, Novel Optical Instrumentation for Biomedical Applications III, 66310D (18 July 2007); https://doi.org/10.1117/12.727646

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available