Multiphoton autofluorescence and second-harmonic generation diagnosis of hepatocellular carcinoma

Yuan Liu; Tzu-Lin Sun; Chuen-Huei Yang; Vladimir A. Hovhannisyan; Wei-Chou Lin; Hsuan-Shu Lee; Chen-Yuan Dong

doi:10.1117/12.764276

14 March 2008 Multiphoton autofluorescence and second-harmonic generation diagnosis of hepatocellular carcinoma

Yuan Liu, Tzu-Lin Sun, Chuen-Huei Yang, Vladimir A. Hovhannisyan, Wei-Chou Lin, Hsuan-Shu Lee, Chen-Yuan Dong

Proceedings Volume 6863, Optical Diagnostics and Sensing VIII; 68630J (2008) https://doi.org/10.1117/12.764276
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

By using two-photon autofluorescence (TPAF) and second harmonics generation (SHG), we imaged hepatocellular carcinoma (HCC) biopsies from the human patients and compared them with the conventional histological biopsies. We found that multiphoton microscopy may be used to obtain label-free images of liver tissues and may be developed into an effective diagnostic tool for liver diseases.

Citation Download Citation

Yuan Liu, Tzu-Lin Sun, Chuen-Huei Yang, Vladimir A. Hovhannisyan, Wei-Chou Lin, Hsuan-Shu Lee, and Chen-Yuan Dong "Multiphoton autofluorescence and second-harmonic generation diagnosis of hepatocellular carcinoma", Proc. SPIE 6863, Optical Diagnostics and Sensing VIII, 68630J (14 March 2008); https://doi.org/10.1117/12.764276

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