Estimation of absorption coefficient in bottom regions in multi-layered turbid media based on the time-domain depth sensitivity: a Monte Carlo investigation

Chie Sato; Miho Shimada; Yoko Hoshi

doi:10.1117/12.764033

22 February 2008 Estimation of absorption coefficient in bottom regions in multi-layered turbid media based on the time-domain depth sensitivity: a Monte Carlo investigation

Chie Sato, Miho Shimada, Yoko Hoshi

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Proceedings Volume 6864, Biomedical Applications of Light Scattering II; 686413 (2008) https://doi.org/10.1117/12.764033
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

We attempted to selectively determine the absorption coefficient (μ_a) of bottom regions in two- and four-layered models with time-domain near infrared measurement. The difference curve in the time-resolved reflectance between a target and a reference medium was divided into segments, and a slope of each segment was calculated to determine depth-dependent μ_a (μ_a^seg). The deviation of μ_a^seg in later time segments from the real μ_a of the bottom layer was μ_a^seg in an earlier time segment to that in a later one. Using this function, we could determine μ_a in the bottom layer for various target media with different conditions.

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Chie Sato, Miho Shimada, and Yoko Hoshi "Estimation of absorption coefficient in bottom regions in multi-layered turbid media based on the time-domain depth sensitivity: a Monte Carlo investigation", Proc. SPIE 6864, Biomedical Applications of Light Scattering II, 686413 (22 February 2008); https://doi.org/10.1117/12.764033

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KEYWORDS

Absorption

Reflectivity

Photons

Picosecond phenomena

Head

Monte Carlo methods

Chromium

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