A cardiac phantom study on quantitative correction of coronary calcium score on multi-detector, dual source, and electron beam tomography for velocity, calcification density, and acquisition time

Marcel J. W. Greuter; Jaap M. Groen; Lieuwe J. Nicolai; Hildebrand Dijkstra; Matthijs Oudkerk

doi:10.1117/12.813617

13 March 2009 A cardiac phantom study on quantitative correction of coronary calcium score on multi-detector, dual source, and electron beam tomography for velocity, calcification density, and acquisition time

Marcel J. W. Greuter, Jaap M. Groen, Lieuwe J. Nicolai, Hildebrand Dijkstra, Matthijs Oudkerk

Author Affiliations +

Proceedings Volume 7258, Medical Imaging 2009: Physics of Medical Imaging; 725835 (2009) https://doi.org/10.1117/12.813617
Event: SPIE Medical Imaging, 2009, Lake Buena Vista (Orlando Area), Florida, United States

Abstract

Objective: To quantify the influence of velocity, calcification density and acquisition time on coronary calcium determination using multi-detector CT, dual-source CT and EBT. Materials and Methods: Artificial arteries with four calcifications of increasing density were attached to a robotic arm to which a linear movement was applied between 0 and 120 mm/s (step 10 mm/s). The phantom was scanned five times on 64-slice MDCT, DSCT and EBT using a standard acquisition protocol and the average Agatston score was determined. Results: Increasing motion artifacts were observed at increasing velocities on all scanners, with increasing severity from EBT to DSCT to 64-slice MDCT. The Agatston score showed a linear dependency on velocity from which a correction factor was derived. This correction factor showed a linear dependency on calcification density (0.92≤R²≤0.95). The slope and offset of this correction factor also showed a linear dependency on acquisition time (0.84≤R²≤0.86). Conclusion: The Agatston score is highly dependent on the average density of individual calcifications. The dependency of the Agatston score on velocity shows a linear behaviour on calcification density. A quantitative method could be derived which corrects the measured calcium score for the influence of velocity, calcification density and acquisition time.

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Marcel J. W. Greuter, Jaap M. Groen, Lieuwe J. Nicolai, Hildebrand Dijkstra, and Matthijs Oudkerk "A cardiac phantom study on quantitative correction of coronary calcium score on multi-detector, dual source, and electron beam tomography for velocity, calcification density, and acquisition time", Proc. SPIE 7258, Medical Imaging 2009: Physics of Medical Imaging, 725835 (13 March 2009); https://doi.org/10.1117/12.813617

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KEYWORDS

Calcium

Arteries

Scanners

Tomography

Computed tomography

Electron beams

Electron tomography

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