Electromechanical reshaping of cartilage is a novel modality that has significant clinical applications in otolaryngology
and plastic surgery. Although EMR dosimetry has been extensively studied, little is known about the mechanisms of
EMR, of which local tissue pH changes is believed to play a role. In this study, rabbit nasal septal cartilage is subject to a
number of experiments aimed at elucidating pH-related changes using phenol red. The lateral extent and magnitude of
pH change as well as factors that impact pH change are studied. Increasing voltage and application appear to increase the
area and intensity of color change. With parameters known to produce thermal tissue injury, a transitional zone likely
representing a confluence of acid-base products is noted in the region around the bend axis. Furthermore, rehydration
and pH indicator application time do not appear to play a role in the quality of pH change. These simple experiments
may provide insight into the role of pH changes in EMR that may allow correlation of dosimetry to tissue damage,
further optimizing the clinical potential of EMR.
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