Design of a novel multi-spectral imaging spectrometer for breast cancer detector based on VHT grating

Zhong Ren; Yan Wu; Guodong Liu; Zhen Huang; Lvming Zeng

doi:10.1117/12.895083

22 August 2011 Design of a novel multi-spectral imaging spectrometer for breast cancer detector based on VHT grating

Zhong Ren, Yan Wu, Guodong Liu, Zhen Huang, Lvming Zeng

Proceedings Volume 8192, International Symposium on Photoelectronic Detection and Imaging 2011: Laser Sensing and Imaging; and Biological and Medical Applications of Photonics Sensing and Imaging; 81924Q (2011) https://doi.org/10.1117/12.895083
Event: International Symposium on Photoelectronic Detection and Imaging 2011, 2011, Beijing, China

Abstract

The ultrasonic imaging, X-mammography, CT imaging and MRI can be applied into the breast cancer diagnosis(BCD). But some factors such as the spatial resolution, contrast and price-performance ratio (PPR) limit their applications. So, a novel BCD technology, that is, multi-spectral imaging is adopted into this paper. It can get more information of the breast tumor and higher identity because it combines the advantages of the spectroscopy and the imaging technology. And in this paper, the multi-spectral light source induced the breast cancer imaging detector(BCID) is designed, the spectrum can cover from the UV to NIR. Meanwhile, a custom-built multi-spectral imaging spectrometer (MSIS) is also developed. And, in order to overcome the stray-light of the light-route system and improve the resolution and light-passing efficiency of the system, the novel volume holography transmissive (VHT) grating instead of the plane or concave grating is used as the diffraction grating in this MSIS. Experimental result show that the novel BCD technology is feasible, it can offer not only the spectral information but also the image of the tumor. The spectrum resolution of the MSIS for BCID based on VHT grating can reach 2nm. Compared with the others, this BCID has more compact structure, faster speed, higher PPR and higher resolution and accuracy. Therefore, this BCID has the potential value in the field of the BCD.

Citation Download Citation

Zhong Ren, Yan Wu, Guodong Liu, Zhen Huang, and Lvming Zeng "Design of a novel multi-spectral imaging spectrometer for breast cancer detector based on VHT grating", Proc. SPIE 8192, International Symposium on Photoelectronic Detection and Imaging 2011: Laser Sensing and Imaging; and Biological and Medical Applications of Photonics Sensing and Imaging, 81924Q (22 August 2011); https://doi.org/10.1117/12.895083

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KEYWORDS

Charge-coupled devices

Diffraction gratings

Multispectral imaging

Breast cancer

Lamps

Spectroscopy

Collimation

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