Depth profile absorber concentration reconstruction using photothermal optical coherence tomography

Roberto Reif; Guangying Guan; Ruikang K. Wang

doi:10.1117/12.910983

30 January 2012 Depth profile absorber concentration reconstruction using photothermal optical coherence tomography

Roberto Reif, Guangying Guan, Ruikang K. Wang

Proceedings Volume 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI; 82132G (2012) https://doi.org/10.1117/12.910983
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

The concentration of photothermal (light-to-heat converters) compounds as a function of depth is determined in solid agar gel phantoms. The system contains an 808nm pump laser, which excites the photothermal compound, and a phase sensitive spectral domain optical coherence tomography system, which detects the changes in the optical pathlength of the sample induced by the temperature increase. The derivation of the model is described, and its parameters are empirically determined. The concentration of photothermal compounds are observed from double layer agar gel phantoms.

Citation Download Citation

Roberto Reif, Guangying Guan, and Ruikang K. Wang "Depth profile absorber concentration reconstruction using photothermal optical coherence tomography", Proc. SPIE 8213, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XVI, 82132G (30 January 2012); https://doi.org/10.1117/12.910983

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