Small NIR-to-VIS upconverting nanoparticles for photodynamic therapy

Meng Earn Lim; Yong Zhang; Justin Jang Hann Chu

doi:10.1117/12.907077

2 February 2012 Small NIR-to-VIS upconverting nanoparticles for photodynamic therapy

Meng Earn Lim, Yong Zhang, Justin Jang Hann Chu

Proceedings Volume 8232, Colloidal Nanocrystals for Biomedical Applications VII; 82320H (2012) https://doi.org/10.1117/12.907077
Event: SPIE BiOS, 2012, San Francisco, California, United States

Abstract

Using a light-based approach known as photodynamic therapy (PDT), we explore a new method in tackling viral pathogens via the excitation of light-sensitive materials called photosensitizers to produce reactive oxygen species which mediates the inactivation of viruses. Photosensitizers are loaded into mesoporous silica coated upconversion nanoparticles to photodynamically inactivate viruses in suspension.

Citation Download Citation

Meng Earn Lim, Yong Zhang, and Justin Jang Hann Chu "Small NIR-to-VIS upconverting nanoparticles for photodynamic therapy", Proc. SPIE 8232, Colloidal Nanocrystals for Biomedical Applications VII, 82320H (2 February 2012); https://doi.org/10.1117/12.907077

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