Variation analysis of flow rate delivered using a blister pump

Sivesh Selvakumar; Rodrigo Linares; Aaron Oppenheimer; Brian Anthony

doi:10.1117/12.907502

14 February 2012 Variation analysis of flow rate delivered using a blister pump

Sivesh Selvakumar, Rodrigo Linares, Aaron Oppenheimer, Brian Anthony

Proceedings Volume 8251, Microfluidics, BioMEMS, and Medical Microsystems X; 82510I (2012) https://doi.org/10.1117/12.907502
Event: SPIE MOEMS-MEMS, 2012, San Francisco, California, United States

Abstract

Components for on-chip storage and delivery of liquid reagent are necessary for many commercial applications of lab-on- a-chip technology. One such system uses a 'blister-pack' that is pushed by an actuator. This paper explores the sensitivity of the flow rate produced by a blister-actuator pair to the expected manufacturing variations in its dimensions. A numerical model of the blister-actuator pair is developed and the tool of Variation Simulation Modeling (VSM) is used to determine the robustness of fluid delivery. For a flow-rate requirement of +/- 10%, the number of out-of-spec parts is found to be less than 0.01%. The critical dimensions that need to be controlled to improve robustness are also identified.

Citation Download Citation

Sivesh Selvakumar, Rodrigo Linares, Aaron Oppenheimer, and Brian Anthony "Variation analysis of flow rate delivered using a blister pump", Proc. SPIE 8251, Microfluidics, BioMEMS, and Medical Microsystems X, 82510I (14 February 2012); https://doi.org/10.1117/12.907502

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