An elastic registration framework to estimate prostate deformation in endorectal MR scans

Muqing Lin; Vijay Parthasarathy; Harsh K. Agarwal; Peter L. Choyke; Baris Turkbey; Tobias Klinder; Jochen Kruecker

doi:10.1117/12.912353

17 February 2012 An elastic registration framework to estimate prostate deformation in endorectal MR scans

Muqing Lin, Vijay Parthasarathy, Harsh K. Agarwal, Peter L. Choyke, Baris Turkbey, Tobias Klinder, Jochen Kruecker

Author Affiliations +

Proceedings Volume 8316, Medical Imaging 2012: Image-Guided Procedures, Robotic Interventions, and Modeling; 831610 (2012) https://doi.org/10.1117/12.912353
Event: SPIE Medical Imaging, 2012, San Diego, California, United States

Abstract

In an effort to improve the accuracy of transrectal ultrasound (TRUS)-guided needle biopsies of the prostate, it is important to understand the non-rigid deformation of the prostate. To understand the deformation of the prostate when an endorectal coil (ERC) is inserted, we develop an elastic registration framework to register prostate MR images with and without ERC. Our registration framework uses robust point matching (RPM) to get the correspondence between the surface landmarks in the source and target volumes followed by elastic body spline (EBS) registration based on the corresponding landmark pairs. Together with the manual rigid alignment, we compared our registration framework based on pure surface landmarks to the registration based on both surface and internal landmarks in the center of the prostate. In addition, we assessed the impact of constraining the warping in the central zone of the prostate using a Gaussian weighting function. Our results show that elastic surface-driven prostate registration is feasible, and that internal landmarks further improve the registration in the central zone while they have little impact on the registration in the peripheral zone of the prostate. Results varied case by case depending on the accuracy of the prostate segmentation and the amount of warping present in each image pair. The most accurate results were obtained when using a Gaussian weighting in the central zone to limit the EBS warping driven by surface points. This suggests that a Gaussian constrain of the warping can effectively compensate for the limitations of the isotropic EBS deformation model, and for erroneous warping inside the prostate created by inaccurate surface landmarks driving the EBS.

Citation Download Citation

Muqing Lin, Vijay Parthasarathy, Harsh K. Agarwal, Peter L. Choyke, Baris Turkbey, Tobias Klinder, and Jochen Kruecker "An elastic registration framework to estimate prostate deformation in endorectal MR scans", Proc. SPIE 8316, Medical Imaging 2012: Image-Guided Procedures, Robotic Interventions, and Modeling, 831610 (17 February 2012); https://doi.org/10.1117/12.912353

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

;

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
8 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Prostate

Image registration

Magnetic resonance imaging

Image segmentation

Biopsy

Rigid registration

Tissues

Show All Keywords

Keywords/Phrases

Search In:

Publication Years