Optimization of the photoacoustic conversion of gold nanorods embedded in biopolymeric scaffolds

Lucia Cavigli; Marella De Angelis; Fulvio Ratto; Paolo Matteini; Francesca Rossi; Sonia Centi; Roberto Pini

doi:10.1117/12.2003173

4 March 2013 Optimization of the photoacoustic conversion of gold nanorods embedded in biopolymeric scaffolds

Lucia Cavigli, Marella De Angelis, Fulvio Ratto, Paolo Matteini, Francesca Rossi, Sonia Centi, Roberto Pini

Proceedings Volume 8581, Photons Plus Ultrasound: Imaging and Sensing 2013; 85810Z (2013) https://doi.org/10.1117/12.2003173
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

Gold nanorods exhibit intense optical absorbance in the near-infrared region of principal interest for applications in biomedical optics, which evokes their use to improve contrast in photoacoustic imaging and selective photothermolysis of cancer. However their limited photostability remains a drawback of practical concern. In particular, when GNRs are irradiated with nanosecond laser pulses in resonance with their plasmon oscillations, there may occur phenomena like reshaping into spherical particles, as well as fragmentation at higher optical fluences, which result into dramatic modifications of their optical absorption bands and substantial loss of photoacoustic conversion efficiency. In this contribution we present an experimental investigation of stability and photoacoustic conversion efficiency from gold nanorods embedded in biomimetic scaffolds.

Citation Download Citation

Lucia Cavigli, Marella De Angelis, Fulvio Ratto, Paolo Matteini, Francesca Rossi, Sonia Centi, and Roberto Pini "Optimization of the photoacoustic conversion of gold nanorods embedded in biopolymeric scaffolds", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85810Z (4 March 2013); https://doi.org/10.1117/12.2003173

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