Photoacoustic radio-frequency spectroscopy (PA-RFS): A technique for monitoring absorber size and concentration

Eno Hysi; Dustin Dopsa; Michael C. Kolios

doi:10.1117/12.2004991

4 March 2013 Photoacoustic radio-frequency spectroscopy (PA-RFS): A technique for monitoring absorber size and concentration

Eno Hysi, Dustin Dopsa, Michael C. Kolios

Author Affiliations +

Proceedings Volume 8581, Photons Plus Ultrasound: Imaging and Sensing 2013; 85813W (2013) https://doi.org/10.1117/12.2004991
Event: SPIE BiOS, 2013, San Francisco, California, United States

Abstract

A photoacoustic technique for monitoring absorber size and concentration is presented. The technique relies on analyzing the power spectra of the radio-frequency signals and taking into account the receiving transducer response in order to remove system dependencies. By normalizing the power spectra, parameters derived from ultrasound tissue characterization (spectral slope and midband fit) can be obtained. Tissue mimicking phantoms were constructed using black polystyrene beads of various sizes and concentrations as absorbers. The spectral slope decreased by 0.63 dB/MHz when the size of the particle increased from 1 μm to 10 μm at every bead concentration. The midband fit was ~4 dB higher for the 10 μm particle and increased linearly with concentration. These results suggest that photoacoustic radiofrequency spectroscopy (PA-RFS) can potentially monitor changes in absorber size and concentration thus improving the ability of photoacoustic imaging to distinguish structural tissue variations.

Citation Download Citation

Eno Hysi, Dustin Dopsa, and Michael C. Kolios "Photoacoustic radio-frequency spectroscopy (PA-RFS): A technique for monitoring absorber size and concentration", Proc. SPIE 8581, Photons Plus Ultrasound: Imaging and Sensing 2013, 85813W (4 March 2013); https://doi.org/10.1117/12.2004991

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available