Persistent luminescence of ZnGa2O4: Cr, an outstanding biomarker for in vivo imaging

S. K. Sharma; A. Bessiere; D. Gourier; L. Binet; B. Viana; N. Basavaraju; K. Priolkar; T. Maldiney; D. Scherman; C. Richard

doi:10.1117/12.2041838

7 March 2014 Persistent luminescence in ZnGa₂O₄:Cr: an outstanding biomarker for in-vivo imaging

S. K. Sharma, A. Bessiere, D. Gourier, L. Binet, B. Viana, N. Basavaraju, K. Priolkar, T. Maldiney, D. Scherman, C. Richard

Author Affiliations +

Proceedings Volume 8982, Optical Components and Materials XI; 898215 (2014) https://doi.org/10.1117/12.2041838
Event: SPIE OPTO, 2014, San Francisco, California, United States

Abstract

ZnGa₂O₄ (ZGO) is a normal spinel. When doped with Cr³⁺ ions, ZGO:Cr becomes a high brightness persistent luminescence material with an emission spectrum perfectly matching the transparency window of living tissues. It allows in vivo mouse imaging with a better signal to background ratio than classical fluorescent NIR probes. The most interesting characteristic of ZGO:Cr lies in the fact that its LLP can be excited with red light, well below its band gap energy and in the transparency window of living tissues. A mechanism based on the trapping of carriers localized around a special type of Cr³⁺ ions namely Cr_N2 can explain this singularity. The antisite defects of the structure are the main responsible traps in the persistent luminescence mechanism. When located around Cr³⁺ ions, they allow, via Cr³⁺ absorption, the storage of not only UV light but also all visible light from the excitation source.

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S. K. Sharma, A. Bessiere, D. Gourier, L. Binet, B. Viana, N. Basavaraju, K. Priolkar, T. Maldiney, D. Scherman, and C. Richard "Persistent luminescence in ZnGa₂O₄:Cr: an outstanding biomarker for in-vivo imaging", Proc. SPIE 8982, Optical Components and Materials XI, 898215 (7 March 2014); https://doi.org/10.1117/12.2041838

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