Rapid non-invasive tests for diagnostics of infectious diseases

Daniel Malamud

doi:10.1117/12.2065332

5 June 2014 Rapid non-invasive tests for diagnostics of infectious diseases

Daniel Malamud

Proceedings Volume 9112, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV; 911203 (2014) https://doi.org/10.1117/12.2065332
Event: SPIE Sensing Technology + Applications, 2014, Baltimore, MD, United States

Abstract

A rapid test for an infectious disease that can be used at point-of-care at a physician’s office, a pharmacy, or in the field is critical for the prompt and appropriate therapeutic intervention. Ultimately by treating infections early on will decrease transmission of the pathogen. In contrast to metabolic diseases or cancer where multiple biomarkers are required, infectious disease targets (e.g. antigen, antibody, nucleic acid) are simple and specific for the pathogen causing the disease. Our laboratory has focused on three major infectious disease; HIV, Tuberculosis, and Malaria. These diseases are pandemic in much of the world thus putting natives, tourists and military personnel at risk for becoming infected, and upon returning to the U.S., transmitting these diseases to their contacts. Our devices are designed to detect antigens, antibodies or nucleic acids in blood or saliva samples in less than 30 minutes. An overview describing the current status of each of the three diagnostic platforms is presented. These microfluidic point-of-care devices will be relatively inexpensive, disposable, and user friendly.

Citation Download Citation

Daniel Malamud "Rapid non-invasive tests for diagnostics of infectious diseases", Proc. SPIE 9112, Sensing Technologies for Global Health, Military Medicine, and Environmental Monitoring IV, 911203 (5 June 2014); https://doi.org/10.1117/12.2065332

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