Image-guided surgery using near-infrared fluorescent light: from bench to bedside

Leonora S. F. Boogerd M.D.; Henricus J. M. Handgraaf M.D.; Cornelis J. H. van de Velde M.D.; Alexander L. Vahrmeijer M.D.

doi:10.1117/12.2079762

4 March 2015 Image-guided surgery using near-infrared fluorescent light: from bench to bedside

Leonora S. F. Boogerd M.D., Henricus J. M. Handgraaf M.D., Cornelis J. H. van de Velde M.D., Alexander L. Vahrmeijer M.D.

Author Affiliations +

Proceedings Volume 9311, Molecular-Guided Surgery: Molecules, Devices, and Applications; 93110U (2015) https://doi.org/10.1117/12.2079762
Event: SPIE BiOS, 2015, San Francisco, California, United States

Abstract

Due to its relatively high tissue penetration, near-infrared (NIR; 700-900 nm) fluorescent light has the potential to visualize structures that need to be resected (e.g. tumors, lymph nodes) and structures that need to be spared (e.g. nerves, ureters, bile ducts). Until now, most clinical trials have focused on suboptimal, non-targeted dyes. Although successful, a new era in image-guided surgery has begun by the introduction of tumor-targeted agents. In this paper, we will describe how tumor-targeted NIR fluorescent imaging can be applied in a clinical setting.

Citation Download Citation

Leonora S. F. Boogerd M.D., Henricus J. M. Handgraaf M.D., Cornelis J. H. van de Velde M.D., and Alexander L. Vahrmeijer M.D. "Image-guided surgery using near-infrared fluorescent light: from bench to bedside", Proc. SPIE 9311, Molecular-Guided Surgery: Molecules, Devices, and Applications, 93110U (4 March 2015); https://doi.org/10.1117/12.2079762

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