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ISSN: 1605-7422

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Authors

Numbers in the index correspond to the last two digits of the six-digit citation identifier (CID) article numbering system used in Proceedings of SPIE. The first four digits reflect the volume number. Base 36 numbering is employed for the last two digits and indicates the order of articles within the volume. Numbers start with 00, 01, 02, 03, 04, 05, 06, 07, 08, 09, 0A, 0B...0Z, followed by 10-1Z, 20-2Z, etc.

Aglyamov, Salavat R., 10

Al-Rekabi, Zeinab, 0I

Arnal, Bastien, 05

Baker, Ryan, 13

Bamber, J. C., 0W

Bregar, Maksimilijan, 17

Brewer, Molly, 0D

Bukshtab, Michael, 18

Bürmen, Miran, 17

Celli, Jonathan P., 0L

Chen, Zhongping, 0V

Choi, Woo June, 0A

Cugmas, Blaž, 17

Ehman, Richard L., 02

Elson, D. S., 0B

Es'haghian, Shaghayegh, 0C

Franco, Walfre, 0R

Friedman, Marc, 18

Gong, Peijun, 0C

Grimwood, A., 0W

Guolla, Louise, 0I

Haase, Kristina, 0I

Han, Zhaolong, 0S, 0Z, 10

Hanna, William, 0L

He, Youmin, 0V

Hickey, Ryan, 0I

Huang, Zhihong, 0U, 0Y

Idugboe, Rita, 10

Jones, Dustin P., 0L

Joy, Joyce, 0Y

Kennedy, Brendan F., 0C

Kennedy, Kelsey M., 0C

Kochevar, Irene E., 0R

Larin, Kirill V., 03, 0F, 0S, 0Z, 10, 14, 16

Larina, Irina V., 0F

Le, Nhan Minh, 0U

Li, Jiasong, 03, 0F, 0S, 0Z, 10, 14

Li, Rui, 0V

Likar, Boštjan, 17

Liu, Chih-Hao, 0Z, 10, 14

Lopez, Andrew L., III, 0F

Ma, Teng, 0V

Martin, James F., 0F

McLaughlin, Robert A., 0C

Meng, Zhaokai, 0P, 13

Messa, A., 0W

Morikawa, Yuka, 0F

Muller, David, 18

Nandy, Sreyankar, 0D

Nguyen, Thu-Mai, 05

O'Donnell, Matthew, 05

Ortega-Martinez, Antonio, 0R

Panin, Vladislav M., 13

Paranjape, Amit, 18

Pelling, Andrew E., 0I

Pernuš, Franjo, 17

Petrov, Georgi I., 0P

Qi, Wenjuan, 0V

Qu, Yueqiao (Rachel), 0V

Raghunathan, Raksha, 10

Salehi, Hassan, 0D

Sampson, David D., 0C

Sanders, Melinda, 0D

Shen, Tueng T., 05

Shung, K. Kirk, 0V

Singh, Manmohan, 03, 0S, 0Z, 10, 14

Skryabina, M.N., 14

Sobol, E., 14

Song, L., 0B

Song, Shaozhen, 05, 0U, 0Y

Sudheendran, Narendran, 10

Sun, Cuiru, 0E

Tao, Ge, 0F

Tremblay, Dominique, 0I

Twa, Michael D., 03, 0S, 0Z, 10

Tziraki, M., 0B

Vantipalli, Srilatha, 0S, 0Z

Wang, Hequn, 0A

Wang, Ruikang K., 05, 0A, 0U, 0Y

Wang, Ruisheng, 0R

Wang, Shang, 03, 0F, 10, 16

Wang, Tianheng, 0D

Wijesinghe, Philip, 0C

Wong, Emily Y., 05

Wu, Chen, 10, 14

Yakovlev, Vladislav V., 0P, 13

Yang, Victor, 0E

Zhou, Qifa, 0V

Zhu, Hong, 0R

Zhu, Jiang, 0V

Zhu, Quing, 0D

Conference Committee

Symposium Chairs

Program Track Chair

Conference Chairs

Conference Program Committee

Session Chairs

Introduction

Optical elastography is the use of optics to characterize cells and tissues based on their mechanical properties. In utilizing the high-resolution capability of optics, this rapidly emerging field builds on and complements the related fields of ultrasound and MR elastography, as well as existing biomechanics methods, such as atomic force microscopy, cell indentation, micropipette aspiration, and particle rheology.

Mechanical forces play an important role in the behavior and development of cells at all spatial scales, from cells and their constituents, to tissues and organs. Such forces profoundly influence the health, structural integrity, and normal function of cells and organs. Accurate determination of cell and tissue biomechanical properties, such as Young's or shear modulus, is a vitally important area. High-resolution optical methods could help further the understanding of mechanical interactions and mechanical properties, with application to cell mechanics, clinical diagnosis, and the understanding of a wide range of diseases.

This second annual conference maintained the vibrant intellectual ambience of the first. It continued to display a strong multidisciplinary character, bringing together technology and applications experts in bioengineering, biophysics, cell biology, clinical sciences, medical imaging, optics and photonics, and tissue engineering. This year, more than 42 contributed papers enhanced two days of invited presentations and posters (a 20% increase over last year). An exceptional keynote and invited speakers headlined the program:

Keynote:

Richard L. Ehman M.D., Mayo Clinic (United States), MRI & mechanobiology: new science at the intersection of engineering and medicine

Invited:

Jeffrey C. Bamber, The Institute of Cancer Research (United Kingdom), Ultrasound elastography: current systems, ongoing research and future potential

Claude Boccara, Institut Langevin (France), Full field OCT and tissue elasticity measurements: a critical view

Andrew E. Pelling, Univ. of Ottawa (Canada), Simultaneous optical and mechanical probes to investigate complex cellular responses to physical cues

Peter Török, Imperial College London (United Kingdom), High numerical aperture Brillouin microscopy

A highlight of this year's meeting was the insight provided by Richard Ehman and Jeff Bamber on magnetic resonance and ultrasound elastography, respectively. The insight that these allied but more mature fields provide into our own field is profound. Special acknowledgement goes to Thorlabs Inc., who sponsored and supported the Keynote Session. Other highlights included the progress and impact made in Brillouin microscopy, and in both the shear wave and compression-based optical coherence elastography approaches. Applications in the anterior eye continued to grow, with some important progress made in breast cancer and interesting new approaches to imaging skin and scar mechanical properties. Optical Elastography and Tissue Biomechanics has confirmed its important role in supporting this emerging area—we look forward with excitement and anticipation to see what the next twelve months will bring. In the meantime, please enjoy reading the papers submitted for this volume.

Kirill V. Larin

David D. Sampson