Magnetic force Optical Coherence Elastography at 1.5 million a-lines per second

Chen Wu; Zhaolong Han; Manmohan Singh; Chih-Hao Liu; Jiasong Li; Alexander Schill; Raksha Raghunathan; Kirill V. Larin

doi:10.1117/12.2214692

8 March 2016 Magnetic force Optical Coherence Elastography at 1.5 million a-lines per second

Chen Wu, Zhaolong Han, Manmohan Singh, Chih-Hao Liu, Jiasong Li, Alexander Schill, Raksha Raghunathan, Kirill V. Larin

Proceedings Volume 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX; 969734 (2016) https://doi.org/10.1117/12.2214692
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

Optical Coherence Elastography (OCE) has been widely used to characterize tissue elasticity. In this paper we introduce a new excitation method using magnetic force to induce shear waves in phantoms and tissues. The shear waves were imaged using an Optical Coherence Tomography system with an A-scan rate of ~1.5 million a-lines per second and the speed of the waves were used to quantify elasticity of different concentrations of agar sampled and porcine liver. The OCE results acquired from this magnetic force excitation were compared with the mechanical compressional tests for validation. The results showed that magnetic force OCE and mechanical testing results were in good agreement, demonstrating the ability of magnetic force OCE to accurately quantify the Young’s modulus of tissue.

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Chen Wu, Zhaolong Han, Manmohan Singh, Chih-Hao Liu, Jiasong Li, Alexander Schill, Raksha Raghunathan, and Kirill V. Larin "Magnetic force Optical Coherence Elastography at 1.5 million a-lines per second", Proc. SPIE 9697, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XX, 969734 (8 March 2016); https://doi.org/10.1117/12.2214692

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