Microfluidic vascular channels in gels using commercial 3D printers

P. Ravi Selvaganapathy; Rana Attalla

doi:10.1117/12.2218401

18 March 2016 Microfluidic vascular channels in gels using commercial 3D printers

P. Ravi Selvaganapathy, Rana Attalla

Proceedings Volume 9705, Microfluidics, BioMEMS, and Medical Microsystems XIV; 97050J (2016) https://doi.org/10.1117/12.2218401
Event: SPIE BiOS, 2016, San Francisco, California, United States

Abstract

This paper details the development of a three dimensional (3D) printing system with a modified microfluidic printhead used for the generation of complex vascular tissue scaffolds. The print-head features an integrated coaxial nozzle that allows the fabrication of hollow, calcium-polymerized alginate tubes that can easily be patterned using 3Dbioprinting techniques. This microfluidic design allows the incorporation of a wide range of scaffold materials as well as biological constituents such as cells, growth factors, and ECM material. With this setup, gel constructs with embedded arrays of hollow channels can be created and used as a potential substitute for blood vessel networks.

Conference Presentation

Citation Download Citation

P. Ravi Selvaganapathy and Rana Attalla "Microfluidic vascular channels in gels using commercial 3D printers", Proc. SPIE 9705, Microfluidics, BioMEMS, and Medical Microsystems XIV, 97050J (18 March 2016); https://doi.org/10.1117/12.2218401

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