Pilot in vivo animal study of bone regeneration by fractional Er: YAG-laser

Gregory B. Altshuler; Andrey V. Belikov; Ksenia V. Shatilova; Andrey I. Yaremenko; Alexander Y. Zernitskiy; Ekaterina A. Zernitckaia

doi:10.1117/12.2229391

21 April 2016 Pilot in vivo animal study of bone regeneration by fractional Er: YAG-laser

Gregory B. Altshuler, Andrey V. Belikov, Ksenia V. Shatilova, Andrey I. Yaremenko, Alexander Y. Zernitskiy, Ekaterina A. Zernitckaia

Author Affiliations +

Proceedings Volume 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS); 991702 (2016) https://doi.org/10.1117/12.2229391
Event: Saratov Fall Meeting 2015, 2015, Saratov, Russian Federation

Abstract

The histological structure of the rabbit parietal bone during its regeneration after fractional Er: YAG-laser (λ=2.94μm) treatment was investigated by hematoxylin and eosin (H&E) stain. In 48 days after fractional laser treatment, bone samples contained micro-cavities and fragments of necrotic tissue with empty cellular lacuna and coagulated protein of bone matrix. In this case, necrotic lesions appeared around the periphery of micro-cavities created by laser radiation. Fragmentation of detrital mass and partial substitution of micro-cavities with fatty bone marrow were observed in bone samples in 100 days after fractional laser treatment, in contrast to the earlier period. Partial filling of micro-cavities edges by fibrous tissue with presence of osteoblasts on their inner surface was observed in 100 days also, that indicates regenerative processes in the bone.

Citation Download Citation

Gregory B. Altshuler, Andrey V. Belikov, Ksenia V. Shatilova, Andrey I. Yaremenko, Alexander Y. Zernitskiy, and Ekaterina A. Zernitckaia "Pilot in vivo animal study of bone regeneration by fractional Er: YAG-laser", Proc. SPIE 9917, Saratov Fall Meeting 2015: Third International Symposium on Optics and Biophotonics and Seventh Finnish-Russian Photonics and Laser Symposium (PALS), 991702 (21 April 2016); https://doi.org/10.1117/12.2229391

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available