OCT velocimetry of vitreous dynamics induced by ocular saccades

Evangeline Priyadharshini Devaraj; Daniel Ruminski; Bartlomiej Kaluzny; J. Sebag; Ireneusz Grulkowski

doi:10.1117/12.2652861

10 May 2023 OCT velocimetry of vitreous dynamics induced by ocular saccades

Evangeline Priyadharshini Devaraj, Daniel Ruminski, Bartlomiej Kaluzny, J. Sebag, Ireneusz Grulkowski

Proceedings Volume PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII; PC123670H (2023) https://doi.org/10.1117/12.2652861
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Aging and myopia are associated with changes in the biomechanical properties of vitreous, inducing fibrous liquefaction. Characterizing vitreous dynamics (rheology) during eye movements can provide a better understanding of biophysical changes in vitreous with disease, as well as provide a quantifiable clinical index of changes from both aging and myopia. Highly sensitive detection of the scattered light intensity in the eye and micrometer image resolution represent advantages of SS-OCT over other technologies to image vitreous. This investigation aims to characterize vitreous dynamics during eye movement. Specifically, we describe a technique for in vivo measurement of vitreous movement tracked over time using high-speed SS-OCT imaging. We also introduce velocimetry analysis of volumetric OCT data sets, enabling the characterization of velocity distributions of vitreous opacities in emmetropic and myopic eyes during horizontal saccades. In vivo imaging was performed with a prototype SS-OCT instrument. We use a manual tracking analysis method to extract velocimetry information on vitreous movement from in vivo data. The velocity of floaters in the vitreous was established by tracking their movement over time, resulting in the hypothesis that the vitreous is more liquid due to the age at which the floaters move faster.

Conference Presentation

Citation Download Citation

Evangeline Priyadharshini Devaraj, Daniel Ruminski, Bartlomiej Kaluzny, J. Sebag, and Ireneusz Grulkowski "OCT velocimetry of vitreous dynamics induced by ocular saccades", Proc. SPIE PC12367, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXVII, PC123670H (10 May 2023); https://doi.org/10.1117/12.2652861

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available