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The fabrication of a stable, reproducible optical imaging phantom is critical to the assessment and optimization of optical imaging systems. In this study, we present a novel design of optical phantom based on metal-doped glass-ceramics. The matrix was doped with nickel ions to imitate the absorption of haemoglobin, and scattering levels representative of tissue were induced through controlled crystallisation in the glass-based phantom at elevated temperature. Our glass-based optical phantom can provide controlled levels of optical scattering and absorption to mimic the optical properties of human tissues with excellent optical homogeneity, and potentially long-term stability and reproducibility.
Mingze Yang,Yunle Wei,Philipp Reineck,Heike Ebendorff-Heidepriem,Jiawen Li, andRobert A McLaughlin
"Development of a glass-based imaging phantom to model the optical properties of human tissue", Proc. SPIE PC12370, Design and Quality for Biomedical Technologies XVI, PC1237001 (6 March 2023); https://doi.org/10.1117/12.2647470
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Mingze Yang, Yunle Wei, Philipp Reineck, Heike Ebendorff-Heidepriem, Jiawen Li, Robert A McLaughlin, "Development of a glass-based imaging phantom to model the optical properties of human tissue," Proc. SPIE PC12370, Design and Quality for Biomedical Technologies XVI, PC1237001 (6 March 2023); https://doi.org/10.1117/12.2647470