Hand-held OCT probe for transcutaneous use to assess various pathologies in real-time

Nick Iftimia; John Grimble; Gopi Maguluri; Aliana Caron; Rahul Anil Sheth; Sanjay Gupta; Amanda McWaters; Savitri Krishnamurthy M.D.

doi:10.1117/12.2649157

6 March 2023 Hand-held OCT probe for transcutaneous use to assess various pathologies in real-time

Nick Iftimia, John Grimble, Gopi Maguluri, Aliana Caron, Rahul Anil Sheth, Sanjay Gupta, Amanda McWaters, Savitri Krishnamurthy M.D.

Author Affiliations +

Proceedings Volume PC12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis; PC123730C (2023) https://doi.org/10.1117/12.2649157
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Real-time assessment of tissue morphology and function is a pressing clinical need. We present a low cost OCT probe based on combined position sensor feedback, as well as a data processing algorithm that enables real-time display of tissue morphology and birefringence. The preliminary evaluation of this instrument on various biological specimens has demonstrated its capability for real-time diagnosis. Its preclinical assessment in vivo on animal models of cancer was performed at MD Anderson Cancer Center. Reliable assessment of tissue morphology and birefringence has been successfully demonstrated.

Conference Presentation

Citation Download Citation

Nick Iftimia, John Grimble, Gopi Maguluri, Aliana Caron, Rahul Anil Sheth, Sanjay Gupta, Amanda McWaters, and Savitri Krishnamurthy M.D. "Hand-held OCT probe for transcutaneous use to assess various pathologies in real-time", Proc. SPIE PC12373, Optical Biopsy XXI: Toward Real-Time Spectroscopic Imaging and Diagnosis, PC123730C (6 March 2023); https://doi.org/10.1117/12.2649157

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