Silicon photonic biosensing: towards portable diagnostics at the point of need

Samantha M. Grist; Lauren S. Puumala; Mohammed A. Al-Qadasi; Avineet Randhawa; Sheri Jahan Chowdhury; Kithmin Wickremasinghe; So Jung Kim; Yas Oloumi Yazdi; Luis G. Alde; Yifei Liu; Nicholas C. Tang; Matthew Mitchell; Lukas Chrostowski; Sudip Shekhar; Karen C. Cheung

doi:10.1117/12.2657809

6 March 2023 Silicon photonic biosensing: towards portable diagnostics at the point of need

Samantha M. Grist, Lauren S. Puumala, Mohammed A. Al-Qadasi, Avineet Randhawa, Sheri Jahan Chowdhury, Kithmin Wickremasinghe, So Jung Kim, Yas Oloumi Yazdi, Luis G. Alde, Yifei Liu, Nicholas C. Tang, Matthew Mitchell, Lukas Chrostowski, Sudip Shekhar, Karen C. Cheung

Author Affiliations +

Proceedings Volume PC12374, Microfluidics, BioMEMS, and Medical Microsystems XXI; PC1237404 (2023) https://doi.org/10.1117/12.2657809
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

Biosensors using silicon photonics (SiP) technology have shown great promise, including the potential to bring the accurate, data-rich diagnostics of lab-grade assays to the point-of-need. In this presentation, we will discuss our work to address three key challenges of SiP biosensors. First, we are tuning the photonic design to meet important performance criteria. Next, we review techniques to functionalize SiP devices, and present our integration of microfluidics with the millimeter-scale sensor chips. Finally, we are using electronic-photonic integration to mitigate a key challenge for point-of-need SiP sensors: the cost and size of the readout system.

Conference Presentation

Citation Download Citation

Samantha M. Grist, Lauren S. Puumala, Mohammed A. Al-Qadasi, Avineet Randhawa, Sheri Jahan Chowdhury, Kithmin Wickremasinghe, So Jung Kim, Yas Oloumi Yazdi, Luis G. Alde, Yifei Liu, Nicholas C. Tang, Matthew Mitchell, Lukas Chrostowski, Sudip Shekhar, and Karen C. Cheung "Silicon photonic biosensing: towards portable diagnostics at the point of need", Proc. SPIE PC12374, Microfluidics, BioMEMS, and Medical Microsystems XXI, PC1237404 (6 March 2023); https://doi.org/10.1117/12.2657809

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