Encoding light for high-through 3D tissue imaging (Conference Presentation)

Peter T. C. So; Dushan N. Wadduwage

doi:10.1117/12.2655637

16 March 2023 Encoding light for high-through 3D tissue imaging (Conference Presentation)

Peter T. C. So, Dushan N. Wadduwage

Proceedings Volume PC12393, Biomedical Applications of Light Scattering XIII; PC1239309 (2023) https://doi.org/10.1117/12.2655637
Event: SPIE BiOS, 2023, San Francisco, California, United States

Abstract

We developed De-scattering with Excitation Patterning or "DEEP,” an extension of the work of Dholakia group. DEEP allows high throughput depth selective wide-field multiphoton imaging in tissues without suffering from blurring due to the scattering of emission photons. We are exploring extensions of this approach along several directions including to simultaneously reconstruct 3D volumes and to combine lifetime imaging to increase information content. In both cases, the extension to a higher dimensional measurement space allows better utilization of the inherent sparsity in many samples allowing for even higher efficiency.

Conference Presentation

Citation Download Citation

Peter T. C. So and Dushan N. Wadduwage "Encoding light for high-through 3D tissue imaging (Conference Presentation)", Proc. SPIE PC12393, Biomedical Applications of Light Scattering XIII, PC1239309 (16 March 2023); https://doi.org/10.1117/12.2655637

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