Ultra-flexible micro-optical coherence tomography enables visualization of the cellular structures of the human cochlea

Fang Hou; Alejandro E. Ortega; Seamus S. Winters; Lillian Wang; Shoumik Lodh; Hinnerk Schulz-Hildebrandt; Konstantina M. Stankovic; Guillermo J. Tearney

doi:10.1117/12.3002701

13 March 2024 Ultra-flexible micro-optical coherence tomography enables visualization of the cellular structures of the human cochlea

Fang Hou, Alejandro E. Ortega, Seamus S. Winters, Lillian Wang, Shoumik Lodh, Hinnerk Schulz-Hildebrandt, Konstantina M. Stankovic, Guillermo J. Tearney

Author Affiliations +

Proceedings Volume PC12818, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2024; (2024) https://doi.org/10.1117/12.3002701
Event: SPIE BiOS, 2024, San Francisco, California, United States

Abstract

Despite the large population that suffers from inner ear diseases, there is a limited understanding and capacity to diagnose the cellular origins of inner ear diseases. One major obstacle is difficulty accessing and observing the inner ear in living patients. We developed an ultra-flexible miniature micro-OCT endoscope that can be inserted into the scala tympani through the round window over more than 20 mm and take cellular resolution OCT images. It has the potential to provide physicians with a new diagnostic approach for tailoring next-generation cochlear implants and administering personalized pharmacologic treatments for a wide variety of inner ear diseases.

Conference Presentation

Citation Download Citation

Fang Hou, Alejandro E. Ortega, Seamus S. Winters, Lillian Wang, Shoumik Lodh, Hinnerk Schulz-Hildebrandt, Konstantina M. Stankovic, and Guillermo J. Tearney "Ultra-flexible micro-optical coherence tomography enables visualization of the cellular structures of the human cochlea", Proc. SPIE PC12818, Imaging, Therapeutics, and Advanced Technology in Head and Neck Surgery and Otolaryngology 2024, (13 March 2024); https://doi.org/10.1117/12.3002701

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