Diffuse correlation spectroscopy (DCS) is an optical technique which is used to estimate blood flow in tissue through the analysis of the temporal fluctuations in light intensity. Recently, the development of interferometric techniques (iDCS/iDWS), have allowed for drastic improvement in measurement SNR. In this work, we build upon the iDCS technique by combining it with another advanced DCS modality, time-domain DCS (TD-DCS). This combination allows for the application of pathlength specific coherent gain, which has the potential to further improve the performance of DCS in the non-invasive measurement of deep tissue blood flow.
|