Post-treatment colorectal cancer tissue often contains fibrosis and edema in tumor bed, photoacoustic elastography is a good tool for evaluating the elasticity change in post treatment colorectal cancer, especially in ultrasonically homogeneous and hypoechogenic regions. We implemented photoacoustic elastography for post-treatment colorectal cancer, developed elasticity phantoms to simulate colon scanning to evaluate elasticity measurement accuracy, applied it in ex vivo tissue scan to evaluate the elasticity change with ultrasound and photoacoustic signal. Results demonstrated good correspondence between ultrasound and photoacoustic elasticity phantom measurements, and showed potential of elasticity measurement with a normal ex vivo colon scan.
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