Digital phantoms generated by spectral and spatial light modulators

Bonghwan Chon; Fuyuki Tokumasu; Ji Youn Lee; David W. Allen; Joseph P. Rice; Jeeseong Hwang

doi:10.1117/1.JBO.20.12.121309

11 September 2015 Digital phantoms generated by spectral and spatial light modulators

Bonghwan Chon, Fuyuki Tokumasu, Ji Youn Lee, David W. Allen, Joseph P. Rice, Jeeseong Hwang

Author Affiliations +

Journal of Biomedical Optics, Vol. 20, Issue 12, 121309 (September 2015). https://doi.org/10.1117/1.JBO.20.12.121309

Abstract

A hyperspectral image projector (HIP) based on liquid crystal on silicon spatial light modulators is explained and demonstrated to generate data cubes. The HIP-constructed data cubes are three-dimensional images of the spatial distribution of spectrally resolved abundances of intracellular light-absorbing oxyhemoglobin molecules in single erythrocytes. Spectrally and spatially resolved image data indistinguishable from the real scene may be used as standard data cubes, so-called digital phantoms, to calibrate image sensors and validate image analysis algorithms for their measurement quality, performance consistency, and interlaboratory comparisons for quantitative biomedical imaging applications.

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Bonghwan Chon, Fuyuki Tokumasu, Ji Youn Lee, David W. Allen, Joseph P. Rice, and Jeeseong Hwang "Digital phantoms generated by spectral and spatial light modulators," Journal of Biomedical Optics 20(12), 121309 (11 September 2015). https://doi.org/10.1117/1.JBO.20.12.121309

Published: 11 September 2015

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KEYWORDS

Spatial light modulators

Hyperspectral imaging

Absorption

Scattering

Image sensors

Liquid crystal on silicon

Image quality

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