Open Access
19 December 2017 Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements
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Abstract
Since the inception of optical coherence tomography (OCT), advancements in imaging system design and handheld probes have allowed for numerous advancements in disease diagnostics and characterization of the structural and optical properties of tissue. OCT system developers continue to reduce form factor and cost, while improving imaging performance (speed, resolution, etc.) and flexibility for applicability in a broad range of fields, and nearly every clinical specialty. An extensive array of components to construct customized systems has also become available, with a range of commercial entities that produce high-quality products, from single components to full systems, for clinical and research use. Many advancements in the development of these miniaturized and portable systems can be linked back to a specific challenge in academic research, or a clinical need in medicine or surgery. Handheld OCT systems are discussed and explored for various applications. Handheld systems are discussed in terms of their relative level of portability and form factor, with mention of the supporting technologies and surrounding ecosystem that bolstered their development. Additional insight from our efforts to implement systems in several clinical environments is provided. The trend toward well-designed, efficient, and compact handheld systems paves the way for more widespread adoption of OCT into point-of-care or point-of-procedure applications in both clinical and commercial settings.
CC BY: © The Authors. Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
Guillermo L. Monroy, Jungeun Won, Darold R. Spillman Jr., Roshan Dsouza, and Stephen A. Boppart "Clinical translation of handheld optical coherence tomography: practical considerations and recent advancements," Journal of Biomedical Optics 22(12), 121715 (19 December 2017). https://doi.org/10.1117/1.JBO.22.12.121715
Received: 6 October 2017; Accepted: 4 December 2017; Published: 19 December 2017
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CITATIONS
Cited by 48 scholarly publications.
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KEYWORDS
Optical coherence tomography

Imaging systems

Tissues

Computer aided design

Ear

In vivo imaging

Surgery

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