A multilayer structure of microbial cells can result in multiple attenuations of electromagnetic waves, making the biological particles have a strong extinction ability. However, the influence of various morphologies on infrared band optical extinction performance of biomaterials is unclear. The combination of shape, dimension, and structure parameters is proposed to evaluate and enhance the optical extinction properties of artificial bioparticles. Combined with the preliminary work of our research group, four artificial biological particles were selected to simulate and calculate their extinction performance with different parameters theoretically based on the discrete-dipole approximation method. The results show the extinction properties of bioparticles with different shapes and dimensions in the 3.0 to 5.0 μm and 8.0 to 14.0 μm wavebands. It was found that the chain-shaped particles with more constituent spheres and a bending angle of 60 deg as well as the ellipsoid-shaped particles with an axis ratio of 1:2 exhibit better extinction properties in the above two bands. Among them, the regulation of extinction efficiency can reach ∼13.92 % and 18.16%.