Point-of-care diagnosis leads to integration of sensors, electrical and optical components in one device and stimulated the area of lab-on-a-chip (LOC) devices where all operations and analysis are realized on a single chip. In LOC applications, the optical components based on interference principles play also important role. The Mach-Zehnder Interferometer (MZI) is well-known photonic device from on-chip applications, especially used in the field of silicon photonics. We proposed design of symmetric MZI based on polymer IP-Dip. Prepared MZIs with interrupted gap in sensing arm were proposed for high sensitive refractive index change detection. The MZIs were realized by laser lithography and optically investigated of different concentration of sucrose/water solutions.
Nowadays, lab on a chip (LOC) applications are very popular in the field of biomedicine. LOC device works with biological materials and enables to arrange conventional laboratory operations on a small chip. Philosophy of LOC applications stands on quick and precise diagnostics process and technology, which uses cheap materials with possibility of rapid prototyping. LOC, as a time saving application, works with small volume of samples and reagents and enables better control over the sample.
We present fabrication method of functional LOC chip for different biomedical microfluidic applications based on direct laser writing (DLW) lithography. We present fabrication of few types of microfluidic and micro-optic structures with different capabilities created by DLW system. The combination of DLW lithography in photoresist layer deposited on glass substrate and polydimethylsiloxane (PDMS) replica molding process were used for patterning of designed microstructures. Prepared microfluidic and micro-optic structures were observed by confocal microscope and microfluidic flow observations were investigated by conventional optical microscope and CCD camera.
Polymer based photonics brings simple and cheap solutions often with interesting results. We present capabilities of some siloxanes focusing on polydimethylsiloxane (PDMS) with unique mechanical and optical properties. In combination of laser lithography technologies with siloxane embossing we fabricate different grating structures with one- and two-dimensional symmetry. Concept of PDMS based thin membranes with patterned surface as an effective diffraction element for modification of radiation pattern diagram of light emitting diodes is here shown. Also the PDMS was used as an alternative material for fabrication of complicated waveguide with implemented Bragg grating. For lab-on-chip applications, we patterned PDMS microstructures for microfluidic and micro-optic devices.
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