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A new low-cost imaging system has been developed for MRI-guided Near-Infrared Spectral Tomography (MRI-NIRST) for breast cancer detection. In this new system, 8 flexible sensing strips with 4 source fibers and 4 photodetectors will be applied directly to the breast, from nipple towards chest-wall, to cover the entire breast. For each source illumination, data will be collected at 32 detector locations. The feasibility of this new imaging system was demonstrated using 3D simulation breast phantoms that created from real breast MR images. Our results indicated that total hemoglobin in a tumor smaller than 1 mm could be recovered with this system.
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Jinchao Feng, Chengpu Wei, Shudong Jiang, Mingwei Zhou, Xu Cao, Brian W. Pogue, Keith D. Paulsen, "MRI guided wearable near infrared spectral tomography: simulation study," Proc. SPIE 11639, Optical Tomography and Spectroscopy of Tissue XIV, 116390D (5 March 2021); https://doi.org/10.1117/12.2578356