Rapid one-step assay for prostate specific antigen in whole blood using an optical immunoassay technology

Grenville Robinson; Timothy Bacarese-Hamilton; Paul M. O'Neill; Janys E. Fletcher; Phelim B. Daniels; Christopher G. Stafford

doi:10.1117/12.201248

10 February 1995 Rapid one-step assay for prostate specific antigen in whole blood using an optical immunoassay technology

Grenville Robinson, Timothy Bacarese-Hamilton, Paul M. O'Neill, Janys E. Fletcher, Phelim B. Daniels, Christopher G. Stafford

Author Affiliations +

Proceedings Volume 2331, Medical Sensors II and Fiber Optic Sensors; (1995) https://doi.org/10.1117/12.201248
Event: International Symposium on Biomedical Optics Europe '94, 1994, Lille, France

Abstract

Much interest has been shown in the development of rapid, one step immunoassay systems for the point-of-care market. The fluorescence capillary fill device (FCFD) is a technology that fulfills the requirements for a system to penetrate this market. The performance of the FCFD is demonstrated in an assay for prostate specific antigen (PSA) in whole blood, the FCFD assay has adequate analytical (a detection limit of less than 0.4 ng/mL PSA and reasonable precision over the clinically relevant range of the assay) and clinical performance (good correlations with commercial PSA assays).

Citation Download Citation

Grenville Robinson, Timothy Bacarese-Hamilton, Paul M. O'Neill, Janys E. Fletcher, Phelim B. Daniels, and Christopher G. Stafford "Rapid one-step assay for prostate specific antigen in whole blood using an optical immunoassay technology", Proc. SPIE 2331, Medical Sensors II and Fiber Optic Sensors, (10 February 1995); https://doi.org/10.1117/12.201248

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