Quantitative studies on photodynamic effects

Tamas Kriska; Judit Jakus; Agnes Keszler; Laszlo Korecz; Dezso Gal

doi:10.1117/12.297817

29 December 1997 Quantitative studies on photodynamic effects

Tamas Kriska, Judit Jakus, Agnes Keszler, Laszlo Korecz, Dezso Gal

Proceedings Volume 3191, Photochemotherapy: Photodynamic Therapy and Other Modalities III; (1997) https://doi.org/10.1117/12.297817
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

According to our hypothesis the interactions of triplet photosensitizer molecules with doublet free radicals generated in vivo (native free radicals) play an important role in the overall photodynamic effect (MTO mechanism). In order to support this mechanism, experiments have been performed recently in vivo, in vitro and in chemical model systems. The precondition of such studies, however, is the measurement of the kinetic parameters of various native free radicals generated in the systems investigated. Experimental results and their kinetic evaluation indicate that the triplet-doublet interactions may actually take place in the overall processes under study.

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Tamas Kriska, Judit Jakus, Agnes Keszler, Laszlo Korecz, and Dezso Gal "Quantitative studies on photodynamic effects", Proc. SPIE 3191, Photochemotherapy: Photodynamic Therapy and Other Modalities III, (29 December 1997); https://doi.org/10.1117/12.297817

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