Analgesic effect of simultaneous exposure to infrared laser radiation and &#956;T magnetic field in rats

Grzegorz Cieslar; Janina Mrowiec; Slawomir Kasperczyk; Karolina Sieron-Stoltny M.D.; Aleksander Sieron M.D.

doi:10.1117/12.762817

12 February 2008 Analgesic effect of simultaneous exposure to infrared laser radiation and &mgr;T magnetic field in rats

Grzegorz Cieslar, Janina Mrowiec, Slawomir Kasperczyk, Karolina Sieron-Stoltny M.D., Aleksander Sieron M.D.

Author Affiliations +

Proceedings Volume 6846, Mechanisms for Low-Light Therapy III; 68460E (2008) https://doi.org/10.1117/12.762817
Event: SPIE BiOS, 2008, San Jose, California, United States

Abstract

The aim of the experiment was to estimate the effect of repeated simultaneous exposures to infrared laser radiation and μT variable magnetic field used in magnetostimulation on pain perception in rats, as well as the involvement of endogenous opioid system in the mechanism of this effect. In experimental group clean-shaven scull of male Wistar rats placed individually in a specially designed plastic chamber were simultaneously exposed to infrared laser radiation (wavelength - 855 nm, mean power - 4,1 mW, energy density - 30 J/cm²) and variable magnetic field of saw-like shape of impulse, at a frequency of basic impulse 180-195 Hz and mean induction value of 120 μT generated by magneto-laser applicator of device for magnetostimulation Viofor JPS (Med & Life, Poland) 12 minutes daily for 2 periods of 5 consecutive days, with 2 days-lasting break between them, while control animals were sham-exposed. The pain perception was determined by means of "hot plate" test on the basis of calculated analgesic index. As a result of repeated exposures a significant increase in analgesic index persisting also till 14^th day after the end of a cycle of exposures was observed. This analgesic effect was inhibited by prior i.p. injection of opioid antagonist - Naloxone.

Citation Download Citation

Grzegorz Cieslar, Janina Mrowiec, Slawomir Kasperczyk, Karolina Sieron-Stoltny M.D., and Aleksander Sieron M.D. "Analgesic effect of simultaneous exposure to infrared laser radiation and &mgr;T magnetic field in rats", Proc. SPIE 6846, Mechanisms for Low-Light Therapy III, 68460E (12 February 2008); https://doi.org/10.1117/12.762817

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available