Cutaneous metastases are relatively rare and often require an invasive biopsy for diagnosis. A novel, non-invasive RCM-OCT device combines the advantage of reflectance confocal microscopy (RCM) and optical coherence tomography (OCT) by providing RCM high-resolution images in the horizontal plane and OCT low-resolution images in the transverse plane. We describe RCM and OCT characteristics of cutaneous metastases using this device to elucidate its utility for diagnosis and management. Seven patients with clinically suspicious cutaneous metastases from breast cancer were imaged using the RCM-OCT device. We found that the RCM-OCT device can detect cutaneous metastases and aid in non-invasive diagnosis.
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