Prof. Brent J. Liu Profile

Prof. Brent J. Liu

Associate Professor at Univ of Southern California

SPIE Involvement:

Conference Program Committee | Author | Editor

Publications (139)

Proceedings Article | 2 April 2024 Presentation + Paper

Utilizing an open-source environment for cognitive-AI in feature detection and quantitative measurements of optical coherence tomography (OCT) images

Anshu Goyal, Seena Pourzand, Sachi Pawooskar-Almeida, M. Wasil Wahi-Anwar, Galo Apolo Aroca, Benjamin Xu, Matthew Brown, Brent Liu

Proceedings Volume 12931, 1293105 (2024) https://doi.org/10.1117/12.3006942

KEYWORDS: Image segmentation, Cornea, Optical coherence tomography, Iris recognition, Eye models, Education and training, Deep learning, Vacuum chambers, Image processing, Eye

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Proceedings Article | 2 April 2024 Paper

Development of decision support tools for gait analysis and rehabilitation utilizing the integrated biomechanics informatics system (IBIS)

Anshu Goyal, Jingqi Hu, Joseph Liu, Harper Stewart, Casey Wiens, Jill McNitt-Gray, Brent Liu

Proceedings Volume 12931, 1293115 (2024) https://doi.org/10.1117/12.3006945

KEYWORDS: Data processing, Databases, Biomedical applications, Data storage, Sports medicine, Biomechanics, Video, Information science, Data modeling, System integration

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Proceedings Article | 2 April 2024 Presentation + Paper

Data-mining and machine learning for knowledge-based treatment planning support in radiation therapy of head and neck cancer using anatomical structure and tumor position

Trent Benedick, Jorge Galvan, Wejdan Ali Alshehri, Ryan Fue, John Asbach, Anh Le, Brent Liu

Proceedings Volume 12931, 1293107 (2024) https://doi.org/10.1117/12.3006269

KEYWORDS: Radiotherapy, Tumors, Anatomy, Neck, Head, Cancer, Oncology, Databases, Information science, Biomedical applications

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Radiation Therapy seeks to treat cancers through the dosage of destructive radiation to target volumes. The treatment plans, detailing the application of radiation dosage, are currently created to adhere to formal guidelines and target dose levels based on physician experience and trial-and-error rather than standard quantitative methods. We propose a web-based informatics application to introduce data driven methods and uniformity into radiation therapy treatment plan creation. We use a quantitative comparison of tumor position and structural anatomy between retrospective cases and a current case undergoing treatment planning to identify useful and relevant retrospective treatment plans for use as templates and reference during current treatment plan creation. The system is based on a database of 403 retrospective DICOM RT objects from University of California Los Angeles and State University of New York Buffalo; Roswell Park as well as the quantitative features we extract from each case. The quantitative identifiers we develop and use in our feature extraction process are the Overlap Value Histogram (OVH) and the Spatial Target Similarity (STS) calculated between the tumor volume and each Organ At Risk (OAR) of irradiation. The similarity between each retrospective case and the current case is the gower’s distance sum of all the earth mover’s distance values calculated between the OVHs and STSs for each OAR in common between the two cases. By calculating the similarity between the current case and each retrospective case we construct a similarity index from which clinicians can select cases they deem useful in their current treatment planning process. Case outcomes will be stored in our database allowing the discovery of correlations between the structural anatomy, tumor position, treatment plans, and outcome, enabling treatment plan benchmarking. These methods allow our informatics system to increase usage of data driven methodologies and standardized practices in radiation therapy treatment planning.

Proceedings Article | 10 April 2023 Paper

A hybrid framework of traditional and deep learning segmentation methods with feature detection for Optical Coherence Tomography (OCT) images

Anshu Goyal, Sachi Pawooskar-Almeida, M. Wasil Wahi-Anwar, Benjamin Xu, Matthew Brown, Brent Liu

Proceedings Volume 12469, 124690H (2023) https://doi.org/10.1117/12.2656170

KEYWORDS: Image segmentation, Deep learning, Image processing algorithms and systems, Education and training, Optical coherence tomography, Iris recognition, Evolutionary algorithms, Cornea, Eye, Anatomy

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Proceedings Article | 10 April 2023 Presentation + Paper

Development of decision support tools for biomechanics research utilizing the integrated biomechanics informatics system (IBIS)

Anshu Goyal, Joseph Liu, Casey Wiens, Harper Stewart, Jill McNitt-Gray, Brent Liu

Proceedings Volume 12469, 124690F (2023) https://doi.org/10.1117/12.2655742

KEYWORDS: Data processing, Databases, Biomechanics, Video, Data modeling, Sports medicine, Decision support systems, System integration, Computing systems, Information science

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Proceedings Article | 10 April 2023 Presentation + Paper

Utilizing data-mining and deep learning methods on retrospective head and neck radiation therapy cases for decision support of individualized treatment planning

Trent Benedick, Mengxuan Li, Emilio Wang, Sachi Pawooskar-Almeida, Anh Le, Brent Liu

Proceedings Volume 12469, 1246906 (2023) https://doi.org/10.1117/12.2656180

KEYWORDS: Radiotherapy, Feature extraction, Cancer, Neck, Head, Databases, Tumors, Decision support systems, Pathology, Standards development

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Proceedings Article | 4 April 2022 Presentation + Paper

An imaging informatics based system with feature detection of AS-optical coherence tomography images for primary angle closure disease

Anshu Goyal, Benjamin Xu, Xinming Li, Lu Niu, Justin Lin, Ryan Li, Brent Liu

Proceedings Volume 12037, 120370G (2022) https://doi.org/10.1117/12.2612736

KEYWORDS: Image segmentation, Cornea, Iris recognition, Algorithm development, Image processing algorithms and systems, Eye, Optical coherence tomography, Imaging systems, Imaging informatics, Image analysis

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Proceedings Article | 4 April 2022 Presentation + Paper

Development of a will-call data mart to store and tag sports medicine data for the integrated biomechanics informatics system (IBIS)

Anshu Goyal, Joseph Liu, Casey Wiens, Harper Stewart, Jill McNitt-Gray, Brent Liu

Proceedings Volume 12037, 120370L (2022) https://doi.org/10.1117/12.2612735

KEYWORDS: Data storage, Databases, Sports medicine, System integration, Information science, Imaging systems, Data modeling, Data integration, Video, Standards development

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Proceedings Article | 4 April 2022 Presentation + Paper

Development of preprocessing and statistical analysis tools in the integrated biomechanics informatics system (IBIS)

Joseph Liu, Casey Wiens, Harper Stewart, Peter Cordi, Mukund Sridhar, Brent Liu, Jill McNitt-Gray

Proceedings Volume 12037, 120370M (2022) https://doi.org/10.1117/12.2612472

KEYWORDS: Video, Databases, Statistical analysis, Detection and tracking algorithms, Algorithm development, Data modeling, Human-machine interfaces, Analytical research, System integration, Injuries

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Proceedings Article | 4 April 2022 Presentation

Dual-tier segmentation approach for hard exudates in fundus images with U-net convolutional neural network

Soumika Guduru, Emma Munch, Veda Murthy, Brent Liu

Proceedings Volume PC12037, PC120370A (2022) https://doi.org/10.1117/12.2612925

KEYWORDS: Image segmentation, Convolutional neural networks, Optical discs, Surveillance, Integration, Blood vessels

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Proceedings Article | 4 April 2022 Presentation

Head and neck cancer radiation therapy treatment planning decision support and benchmarking

Trent Benedick, Xinming Li, Lisa Meng, Eric Manning, Ahn Le, Brent Liu

Proceedings Volume PC12037, PC120370C (2022) https://doi.org/10.1117/12.2613538

KEYWORDS: Radiotherapy, Tumors, Databases, Feature extraction, Detection and tracking algorithms, Information science

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Proceedings Article | 15 March 2019 Presentation + Paper

The development of an imaging informatics-based platform and data viewer interface to support sports performance and injury prevention in track and field athletes

Joseph Liu, Ximing Wang, Sneha Verma, Jill McNitt-Gray, Brent Liu

Proceedings Volume 10954, 1095404 (2019) https://doi.org/10.1117/12.2513774

KEYWORDS: Video, Human-machine interfaces, Injuries, Data processing, Video processing, Information science, Data acquisition, Data storage, Databases, Imaging systems

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Proceedings Article | 15 March 2019 Presentation + Paper

Multimedia data handling and integration for rehabilitation research

Sneha Verma, Jill McNitt-Gray, Brent Liu

Proceedings Volume 10954, 1095405 (2019) https://doi.org/10.1117/12.2513046

KEYWORDS: Data modeling, Multimedia, Data storage, Data integration, Data acquisition, Medical imaging, Databases, Video, Standards development, Imaging informatics

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With advances in data acquisition devices, current rehabilitation research involves extensive experimental trials to identify the underlying cause or long-term consequences of certain pathologies and to improve motor functions by examining the movement patterns of affected individuals. For research focused on movement analysis, high volume of multimedia data such as high-speed video is acquired with other data types such as surveys, spreadsheets, force data recordings from instrumented surfaces etc. These datasets are recorded from various standalone sources however multimedia data in rehabilitation research is often requires analysis in context with subject’s medical history, treatment plan or progress. But in current research workflow, no pathways and data handling protocols are defined to successfully achieve comprehensive integration of multimedia data, for various data types collected at various stages in a clinical trial, different data handling protocols needs to be defined and designed. In this presentation, we will be focusing on multimedia data only such as high-speed video files collected during a clinical trial. Multimedia data collected during a rehabilitation research often end up residing in an isolated space. Our aim for this presentation is to design and evaluate data handling steps for successful integration, storage and retrieval of multimedia data. This presentation focuses on establishing tools that can be used between data acquisition step to data storage for media files. We will present method for metadata creation for multimedia data based on the electronic patient data (ePR) model design as well as two common standards of medical imaging, DICOM and PACS to form an effective data handling protocol. For evaluation, data set collected for wheelchair movement analysis study at Rancho Los Amigos National Rehabilitation Center in Downey, California will be used. The broader aim of this paper is to present development of standards and protocols for multimedia data handling in a clinical workflow based on medical imaging informatics.

Proceedings Article | 15 March 2019 Presentation + Paper

The application of deep learning framework in quantifying retinal structures on ophthalmic image in research eye-PACS

Moye Yu, Siliang Zhang, Brent Liu, Shenghui Zhao, Aimin Sang, Jiancheng Dong, Huiqun Wu

Proceedings Volume 10954, 1095402 (2019) https://doi.org/10.1117/12.2512458

KEYWORDS: Image segmentation, Macula, Picture Archiving and Communication System, Image processing, Visualization, Data modeling, Human-machine interfaces, Prototyping, Analytical research, Target detection

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Proceedings Article | 15 March 2019 Presentation + Paper

Head and neck cancer radiation therapy decision support

Trent Benedick, Veda Murthy, Rhea Koparde, Maying Shi, Sabrina Lieu, Siliang Zhang, Benjamin Yao, Anh Le, Brent Liu

Proceedings Volume 10954, 109540Y (2019) https://doi.org/10.1117/12.2513075

KEYWORDS: Cancer, Radiotherapy, Decision support systems, Head, Neck, Feature extraction, Tumors, Databases, Oncology, Information science

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Currently the methods used to develop radiation therapy treatment plans for head and neck cancers rely on clinician experience and a small set of universal guidelines which result in inconsistent and variable methods. Data driven support can provide assistance to clinicians by reducing inconsistency associated with treatment planning and provide empirical estimates to minimize the radiation to healthy organs near the tumor. We created a database of DICOM RT objects which stores historical cases and when a new DICOM object is uploaded it will return a set of similar treatment plans to assist the clinician in creating the treatment plan for the current patient. The database works first by extracting features from DICOM RT object to quantitatively compare and evaluate the similarity of cases enabling the system to mine for cases with defined similarity. The feature extraction methods are based on the spatial relationships between the tumors and organs at risk which allows the generation the overlap volume histogram and spatial target similarity which demonstrate the volumetric and locational similarity between the organ at risk and the tumor. It is useful to find cases with similar tumor anatomy because this similarity translates to similarity in radiation dosage. The developed system was applied to three different RT sites, University of California Los Angeles, Technical University at Munich and State University of New York Buffalo; Roswell Park, with a total of 247 cases to evaluate the system for both inter- and intra- institutional best practices and results. Future roadmap will be discussed for correlating outcomes results to the decision support system which will enhance the overall performance and utilization of the decision support system in the RT workflow. In the future, because this database returns similar historical cases to a current one this could be a worthwhile decision support tool for clinicians as they create new radiation therapy treatment plans.

Proceedings Article | 15 March 2019 Presentation + Paper

Fundus Analysis Software Tool (FAST): development of software integrating CAD with the EHR for the longitudinal study of fundus images

Veda Murthy, Manjula Shankar, Justin Lin, Sabrina Lieu, Mayur Patel, Heaven Post, Hemanth Murthy, Brent Liu

Proceedings Volume 10954, 1095406 (2019) https://doi.org/10.1117/12.2512068

KEYWORDS: Image segmentation, Computer aided design, Algorithm development, Image processing algorithms and systems, Software development, Computer aided diagnosis and therapy, Image processing, Java

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Proceedings Article | 6 March 2018 Paper

The development of an imaging informatics-based multi-institutional platform to support sports performance and injury prevention in track and field

Joseph Liu, Ximing Wang, Sneha Verma, Jill McNitt-Gray, Brent Liu

Proceedings Volume 10579, 105791Q (2018) https://doi.org/10.1117/12.2297665

KEYWORDS: Data storage, Video, Information science, Data processing, Injuries, Imaging systems, Standards development, Human-machine interfaces, Imaging informatics, Data acquisition

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Proceedings Article | 6 March 2018 Presentation + Paper

The application of deep learning for diabetic retinopathy prescreening in research eye-PACS

Siliang Zhang, Huiqun Wu, Veda Murthy, Ximing Wang, Lin Cao, John Schwartz, Jorge Hernandez, Gustavo Rodriguez, Brent Liu

Proceedings Volume 10579, 1057913 (2018) https://doi.org/10.1117/12.2296673

KEYWORDS: Picture Archiving and Communication System, Cameras, Algorithm development, Image analysis, Image classification, Neural networks, Pathology, Human-machine interfaces, Databases, Image resolution

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Proceedings Article | 6 March 2018 Paper

Medical imaging informatics based solutions for human performance analytics

Sneha Verma, Jill McNitt-Gray, Brent Liu

Proceedings Volume 10579, 105791R (2018) https://doi.org/10.1117/12.2297663

KEYWORDS: Data modeling, Imaging informatics, Analytics, Multimedia, Data storage, Analytical research, Visualization, Imaging systems, Medical imaging, Information science

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Proceedings Article | 6 March 2018 Presentation + Paper

The development of an ophthalmologic imaging CADe structured report for retinal image radiomics research

Huiqun Wu, Joseph Liu, Siliang Zhang, Alyssa Zhu, Christopher Sulistio, Jingjing Li, Aimin Sang, Jiancheng Dong, Brent Liu

Proceedings Volume 10579, 1057910 (2018) https://doi.org/10.1117/12.2294918

KEYWORDS: Computer aided diagnosis and therapy, Picture Archiving and Communication System, Clinical trials, Photography, Digital imaging, Image analysis, Algorithm development, Medical imaging, Analytical research, Human-machine interfaces

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Proceedings Article | 3 May 2017 Presentation

Evaluation of longitudinal tracking and data mining for an imaging informatics-based multiple sclerosis e-folder (Conference Presentation)

Kevin Ma, Sydney Forsyth, Lilyana Amezcua, Brent Liu

Proceedings Volume 10138, 101380K (2017) https://doi.org/10.1117/12.2256579

KEYWORDS: Data mining, Analytical research, Data analysis, Information science, Data storage, Image storage, Automatic tracking, Clinical research, Human-machine interfaces, Imaging systems

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Proceedings Article | 13 March 2017 Paper

Differentiating malignant from benign breast tumors on acoustic radiation force impulse imaging using fuzzy-based neural networks with principle component analysis

Hsiao-Chuan Liu, Yi-Hong Chou, Chui-Mei Tiu, Chi-Wen Hsieh, Brent Liu, K. Kirk Shung

Proceedings Volume 10138, 1013818 (2017) https://doi.org/10.1117/12.2263476

KEYWORDS: Elastography, Acoustics, Neural networks, Breast, Ultrasonography, Tissues, Fuzzy logic, Tumors, Fractal analysis, Principal component analysis, Breast cancer, Statistical analysis

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Many modalities have been developed as screening tools for breast cancer. A new screening method called acoustic radiation force impulse (ARFI) imaging was created for distinguishing breast lesions based on localized tissue displacement. This displacement was quantitated by virtual touch tissue imaging (VTI). However, VTIs sometimes express reverse results to intensity information in clinical observation. In the study, a fuzzy-based neural network with principle component analysis (PCA) was proposed to differentiate texture patterns of malignant breast from benign tumors. Eighty VTIs were randomly retrospected. Thirty four patients were determined as BI-RADS category 2 or 3, and the rest of them were determined as BI-RADS category 4 or 5 by two leading radiologists. Morphological method and Boolean algebra were performed as the image preprocessing to acquire region of interests (ROIs) on VTIs. Twenty four quantitative parameters deriving from first-order statistics (FOS), fractal dimension and gray level co-occurrence matrix (GLCM) were utilized to analyze the texture pattern of breast tumors on VTIs. PCA was employed to reduce the dimension of features. Fuzzy-based neural network as a classifier to differentiate malignant from benign breast tumors. Independent samples test was used to examine the significance of the difference between benign and malignant breast tumors. The area Az under the receiver operator characteristic (ROC) curve, sensitivity, specificity and accuracy were calculated to evaluate the performance of the system. Most all of texture parameters present significant difference between malignant and benign tumors with p-value of less than 0.05 except the average of fractal dimension. For all features classified by fuzzy-based neural network, the sensitivity, specificity, accuracy and Az were 95.7%, 97.1%, 95% and 0.964, respectively. However, the sensitivity, specificity, accuracy and Az can be increased to 100%, 97.1%, 98.8% and 0.985, respectively if PCA was performed to reduce the dimension of features. Patterns of breast tumors on VTIs can effectively be recognized by quantitative texture parameters, and differentiated malignant from benign lesions by fuzzy-based neural network with PCA.

Proceedings Article | 13 March 2017 Paper

The design and integration of retinal CAD-SR to diabetes patient ePR system

Huiqun Wu, Yufang Wei, Brent Liu, Yujuan Shang, Lili Shi, Kui Jiang, Jiancheng Dong

Proceedings Volume 10138, 1013819 (2017) https://doi.org/10.1117/12.2264642

KEYWORDS: Computer aided design, Computer aided diagnosis and therapy, Algorithm development, Detection and tracking algorithms, Medicine, Data modeling, Cameras, Image compression, Databases, Medical imaging

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Proceedings Article | 13 March 2017 Presentation + Paper

Evaluation of a web based informatics system with data mining tools for predicting outcomes with quantitative imaging features in stroke rehabilitation clinical trials

Ximing Wang, Bokkyu Kim, Ji Hoon Park, Erik Wang, Sydney Forsyth, Cody Lim, Ragini Ravi, Sarkis Karibyan, Alexander Sanchez, Brent Liu

Proceedings Volume 10138, 101380J (2017) https://doi.org/10.1117/12.2256242

KEYWORDS: Imaging systems, Clinical trials, Information science, Data modeling, Feature extraction, Data mining, Medical imaging, System integration, Databases, Optimization (mathematics), Statistical analysis, Data analysis, Knowledge discovery

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Proceedings Article | 13 March 2017 Presentation + Paper

The development of a decision support system with an interactive clinical user interface for estimating treatment parameters in radiation therapy in order to reduce radiation dose in head and neck patients

Sneha Verma, Joseph Liu, Ruchi Deshpande, John DeMarco, Brent Liu

Proceedings Volume 10138, 101380M (2017) https://doi.org/10.1117/12.2257029

KEYWORDS: Radiotherapy, Data processing, Technologies and applications, Medical imaging, Decision support systems, Human-machine interfaces, Head, Neck, Tissues, Tumors, Databases, Prototyping, Data modeling, Information science

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Proceedings Article | 25 March 2016 Paper

Development of a web based informatics system utilizing quantitative imaging features for predicting outcomes in stroke rehabilitation clinical trials

Ximing Wang, Ji Hoon Park, Jeffrey Tse, Brent Liu

Proceedings Volume 9789, 97890Y (2016) https://doi.org/10.1117/12.2218093

KEYWORDS: Clinical trials, Imaging systems, Data modeling, Systems modeling, Databases, Imaging informatics, Information science, Data mining, Data analysis, Feature extraction, Knowledge discovery, Process modeling

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Proceedings Article | 25 March 2016 Paper

Lesion registration for longitudinal disease tracking in an imaging informatics-based multiple sclerosis eFolder

Kevin Ma, Joseph Liu, Xuejun Zhang, Alex Lerner, Mark Shiroishi, Lilyana Amezcua, Brent Liu

Proceedings Volume 9789, 97890F (2016) https://doi.org/10.1117/12.2217903

KEYWORDS: Image registration, Brain, Magnetic resonance imaging, Algorithm development, Computer aided design, Data storage, Image storage, Clinical research, Data analysis, Brain mapping, Neuroimaging, Computer aided diagnosis and therapy, Databases, Scanning probe microscopy

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Proceedings Article | 25 March 2016 Paper

Multi-site evaluation of a clinical decision support system for radiation therapy

Ruchi Deshpande, John DeMarco, Kerstin Kessel, Brent Liu

Proceedings Volume 9789, 97890E (2016) https://doi.org/10.1117/12.2217733

KEYWORDS: Decision support systems, Imaging informatics, Radiotherapy, Databases, Head, Neck, Cancer, Tissues, Systems modeling, Process modeling, Data modeling, Computed tomography, Tumors, Feature extraction, Radiation oncology

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Proceedings Article | 25 March 2016 Paper

Comparing the role of shape and texture on staging hepatic fibrosis from medical imaging

Xuejun Zhang, Ryan Louie, Brent Liu, Xin Gao, Xiaomin Tan, Xianghe Qu, Liling Long

Proceedings Volume 9789, 97890W (2016) https://doi.org/10.1117/12.2216560

KEYWORDS: Liver, Medical imaging, Computer aided diagnosis and therapy, Liver cancer, Cancer, Biopsy, Computed tomography, Image classification, Feature extraction, Shape analysis, Data modeling, Computing systems, Samarium

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Proceedings Article | 25 March 2016 Paper

A handheld computer-aided diagnosis system and simulated analysis

Mingjian Su, Xuejun Zhang, Brent Liu, Kening Su, Ryan Louie

Proceedings Volume 9789, 97890P (2016) https://doi.org/10.1117/12.2216421

KEYWORDS: Skin, Computer aided diagnosis and therapy, Computing systems, Distributed computing, Feature extraction, Image processing, Image retrieval, Telecommunications, CAD systems, Pattern recognition

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Proceedings Article | 25 March 2016 Paper

Multi-disciplinary data organization and visualization models for clinical and pre-clinical studies: A case study in the application of proton beam radiosurgery for treating spinal cord injury related pain

Sneha Verma, Brent Liu

Proceedings Volume 9789, 97890U (2016) https://doi.org/10.1117/12.2216367

KEYWORDS: Data mining, Databases, Medicine, Expectation maximization algorithms

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Proceedings Article | 22 December 2015 Paper

Multidimensional Interactive Radiology Report and Analysis: standardization of workflow and reporting for renal mass tracking and quantification

Darryl Hwang, Kevin Ma, Fernando Yepes, Mridula Nadamuni, Megha Nayyar, Brent Liu, Vinay Duddalwar, Natasha Lepore

Proceedings Volume 9681, 96810C (2015) https://doi.org/10.1117/12.2211526

KEYWORDS: Radiology, Kidney, 3D metrology, 3D modeling, 3D image processing, Image segmentation, Tumors, Image processing, Natural surfaces, 3D imaging standards

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Proceedings Article | 17 March 2015 Paper

An imaging informatics-based system to support animal studies for treating pain in spinal cord injury utilizing proton-beam radiotherapy

Sneha Verma, Brent Liu, Daila Gridley, Xiao Mao, Nikhil Kotha

Proceedings Volume 9418, 941811 (2015) https://doi.org/10.1117/12.2081550

KEYWORDS: Imaging systems, Spinal cord, Image analysis, Data modeling, Injuries, Image segmentation, Databases, Radiotherapy, Imaging informatics, Medicine

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Proceedings Article | 17 March 2015 Paper

Design and evaluation of an imaging informatics system for analytics-based decision support in radiation therapy

Ruchi Deshpande, John DeMarco, Brent Liu

Proceedings Volume 9418, 94180Y (2015) https://doi.org/10.1117/12.2082862

KEYWORDS: Decision support systems, Radiotherapy, Databases, Cancer, Data modeling, Imaging informatics, Head, Neck, Oncology, Tumors

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Proceedings Article | 17 March 2015 Paper

Big data in multiple sclerosis: development of a web-based longitudinal study viewer in an imaging informatics-based eFolder system for complex data analysis and management

Kevin Ma, Ximing Wang, Alex Lerner, Mark Shiroishi, Lilyana Amezcua, Brent Liu

Proceedings Volume 9418, 941809 (2015) https://doi.org/10.1117/12.2082650

KEYWORDS: Data analysis, Brain, Imaging systems, Computer aided design, Databases, Magnetic resonance imaging, Data mining, Medical imaging, Imaging informatics, Analytical research

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Proceedings Article | 17 March 2015 Paper

Characterizing stroke lesions using digital templates and lesion quantification tools in a web-based imaging informatics system for a large-scale stroke rehabilitation clinical trial

Ximing Wang, Matthew Edwardson, Alexander Dromerick, Carolee Winstein, Jing Wang, Brent Liu

Proceedings Volume 9418, 94180E (2015) https://doi.org/10.1117/12.2082735

KEYWORDS: Imaging systems, Clinical trials, Brain, Imaging informatics, Neuroimaging, Medical imaging, Magnetic resonance imaging, Analytical research, Visual analytics, Visualization

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Previously, we presented an Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (ICARE) imaging informatics system that supports a large-scale phase III stroke rehabilitation trial. The ePR system is capable of displaying anonymized patient imaging studies and reports, and the system is accessible to multiple clinical trial sites and users across the United States via the web. However, the prior multicenter stroke rehabilitation trials lack any significant neuroimaging analysis infrastructure. In stroke related clinical trials, identification of the stroke lesion characteristics can be meaningful as recent research shows that lesion characteristics are related to stroke scale and functional recovery after stroke. To facilitate the stroke clinical trials, we hope to gain insight into specific lesion characteristics, such as vascular territory, for patients enrolled into large stroke rehabilitation trials. To enhance the system’s capability for data analysis and data reporting, we have integrated new features with the system: a digital brain template display, a lesion quantification tool and a digital case report form. The digital brain templates are compiled from published vascular territory templates at each of 5 angles of incidence. These templates were updated to include territories in the brainstem using a vascular territory atlas and the Medical Image Processing, Analysis and Visualization (MIPAV) tool. The digital templates are displayed for side-by-side comparisons and transparent template overlay onto patients’ images in the image viewer. The lesion quantification tool quantifies planimetric lesion area from user-defined contour. The digital case report form stores user input into a database, then displays contents in the interface to allow for reviewing, editing, and new inputs. In sum, the newly integrated system features provide the user with readily-accessible web-based tools to identify the vascular territory involved, estimate lesion area, and store these results in a web-based digital format.

Proceedings Article | 19 March 2014 Paper

An imaging informatics-based system utilizing DICOM objects for treating pain in spinal cord injury patients utilizing proton beam radiotherapy

Sneha Verma, Brent Liu, Sophia Chun, Daila Gridley

Proceedings Volume 9039, 90390W (2014) https://doi.org/10.1117/12.2044433

KEYWORDS: Imaging systems, Spinal cord, Data modeling, Injuries, Radiotherapy, Databases, Imaging informatics, Computed tomography, Skull, Positron emission tomography

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Proceedings Article | 19 March 2014 Paper

A web-based neurological pain classifier tool utilizing Bayesian decision theory for pain classification in spinal cord injury patients

Sneha Verma, Sophia Chun, Brent Liu

Proceedings Volume 9039, 90390E (2014) https://doi.org/10.1117/12.2044434

KEYWORDS: Injuries, Spinal cord, Decision support systems, Classification systems, Prototyping, Algorithm development, Machine learning, Imaging informatics, Algorithms, Human-machine interfaces

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Proceedings Article | 19 March 2014 Paper

Development of a web-based DICOM-SR viewer for CAD data of multiple sclerosis lesions in an imaging informatics-based efolder

Kevin Ma, Jonathan Wong, Mark Zhong, Jeff Zhang, Brent Liu

Proceedings Volume 9039, 903903 (2014) https://doi.org/10.1117/12.2044076

KEYWORDS: Computer aided design, Brain, Computer aided diagnosis and therapy, Magnetic resonance imaging, Data conversion, MATLAB, Imaging systems, Neuroimaging, Data storage, Databases

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Proceedings Article | 19 March 2014 Paper

A collaborative framework for contributing DICOM RT PHI (Protected Health Information) to augment data mining in clinical decision support

Ruchi Deshpande, Wanwara Thuptimdang, John DeMarco, Brent Liu

Proceedings Volume 9039, 90390K (2014) https://doi.org/10.1117/12.2044010

KEYWORDS: Data modeling, Decision support systems, Databases, Computed tomography, Radiotherapy, Data mining, Tumors, Data processing, Imaging informatics, Machine learning

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Proceedings Article | 19 March 2014 Paper

Development of a user customizable imaging informatics-based intelligent workflow engine system to enhance rehabilitation clinical trials

Ximing Wang, Clarisa Martinez, Jing Wang, Ye Liu, Brent Liu

Proceedings Volume 9039, 90390G (2014) https://doi.org/10.1117/12.2044411

KEYWORDS: Clinical trials, Imaging systems, Intelligence systems, Multimedia, Information science, Databases, Software development, Picture Archiving and Communication System, Imaging informatics, Distance measurement

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Proceedings Article | 19 March 2014 Paper

A concept of a generalized electronic patient record for personalized medicine

Jens Meier, Ruchi Deshpande, Brent Liu, Thomas Neumuth

Proceedings Volume 9039, 903907 (2014) https://doi.org/10.1117/12.2043429

KEYWORDS: Tumors, Radiotherapy, Cadmium sulfide, Decision support systems, Telecommunications, Head, Neck, Databases, Surgery, Medicine

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Proceedings Article | 29 March 2013 Paper

Role of an imaging informatics-based DICOM-RT cancer registry in evaluating treatment parameters of IMRT for prostate cancer

Ruchi Deshpande, Alyssa Zhou, Jeffrey Zhang, John DeMarco, Brent Liu

Proceedings Volume 8674, 86740O (2013) https://doi.org/10.1117/12.2007429

KEYWORDS: Cancer, Oncology, Bladder, Imaging systems, Databases, Radiotherapy, Tumors, Computed tomography, Data modeling, Rectum

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Proceedings Article | 29 March 2013 Paper

A multimedia system for decision support in neurological classification of pain in spinal cord injury patients

Sneha Verma, Sophia Chun, Brent Liu

Proceedings Volume 8674, 867409 (2013) https://doi.org/10.1117/12.2007721

KEYWORDS: Spinal cord, Injuries, Decision support systems, Classification systems, Data storage servers, Data modeling, Databases, Imaging systems, Data acquisition, Nervous system

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Proceedings Article | 29 March 2013 Paper

Imaging informatics-based multimedia ePR system for data management and decision support in rehabilitation research

Ximing Wang, Sneha Verma, Yi Qin, Josh Sterling, Alyssa Zhou, Jeffrey Zhang, Clarisa Martinez, Narissa Casebeer, Hyunwook Koh, Carolee Winstein, Brent Liu

Proceedings Volume 8674, 86740P (2013) https://doi.org/10.1117/12.2008585

KEYWORDS: Multimedia, Data storage, Imaging systems, Video, Data modeling, Data centers, Data processing, Decision support systems, Medical imaging, Electromyography

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Proceedings Article | 29 March 2013 Paper

Integration of imaging informatics-based multiple sclerosis eFolder system for multi-site clinical trials utilizing IHE workflow profiles

Kevin Ma, Nakul Reddy, Ruchi Deshpande, Lilyana Amezcua, Brent Liu

Proceedings Volume 8674, 86740A (2013) https://doi.org/10.1117/12.2008266

KEYWORDS: Computer aided design, Imaging systems, Databases, Data storage, Human-machine interfaces, Magnetic resonance imaging, Clinical trials, Computing systems, Computer aided diagnosis and therapy, System integration

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Proceedings Article | 6 April 2012 Paper

Comparison of 2D versus 3D mammography with screening cases: an observer study

James Reza Fernandez, Ruchi Deshpande, Linda Hovanessian-Larsen, Brent Liu

Proceedings Volume 8318, 831818 (2012) https://doi.org/10.1117/12.912497

KEYWORDS: Mammography, 3D displays, Breast, Breast cancer, Cancer, Tissues, 3D image processing, Diagnostics, 3D acquisition, Pathology

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Proceedings Article | 27 February 2012 Paper

A web-based electronic patient record (ePR) system for data integration in movement analysis research on wheel-chair users to minimize shoulder pain

Ruchi Deshpande, Philip Requejo, Erry Sutisna, Ximing Wang, Margaret Liu, Sarah McNitt-Gray, Puja Ruparel, Brent Liu

Proceedings Volume 8319, 83190W (2012) https://doi.org/10.1117/12.911074

KEYWORDS: Data modeling, Video, Analytical research, Motion analysis, Databases, System integration, Data integration, Data analysis, Injuries, Imaging informatics

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Proceedings Article | 17 February 2012 Paper

An imaging informatics-based ePR (electronic patient record) system for providing decision support in evaluating dose optimization in stroke rehabilitation

Brent Liu, Carolee Winstein, Ximing Wang, Matt Konersman, Clarisa Martinez, Nicolas Schweighofer

Proceedings Volume 8319, 83190V (2012) https://doi.org/10.1117/12.912952

KEYWORDS: Imaging systems, Data modeling, Clinical trials, Data acquisition, Decision support systems, Magnetic resonance imaging, Databases, Electronic imaging, Diffusion tensor imaging, Imaging informatics

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Proceedings Article | 16 February 2012 Paper

A multimedia comprehensive informatics system with decision support tools for a multi-site collaboration research of stroke rehabilitation

Ximing Wang, Jorge Documet, Kathleen Garrison, Carolee Winstein, Brent Liu

Proceedings Volume 8319, 83190U (2012) https://doi.org/10.1117/12.910971

KEYWORDS: Imaging systems, Databases, Decision support systems, Head, Information science, Imaging informatics, Cadmium, Data storage, Compact discs, Multimedia

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Proceedings Article | 16 February 2012 Paper

Lesion comparison of multiple sclerosis in hispanic and caucasian patients utilizing an imaging informatics-based eFolder system

Kevin Ma, James Fernandez, Lilyana Amezcua, Alex Lerner, Mark Shiroishi, Brent Liu

Proceedings Volume 8319, 83190G (2012) https://doi.org/10.1117/12.911452

KEYWORDS: Computer aided design, Computer aided diagnosis and therapy, Magnetic resonance imaging, Brain, Imaging systems, Neuroimaging, Image segmentation, 3D image processing, Data integration, Visualization

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Proceedings Article | 16 February 2012 Paper

Utilization of DICOM multi-frame objects for integrating kinetic and kinematic data with raw videos in movement analysis of wheel-chair users to minimize shoulder pain

Ruchi Deshpande, Han Li, Philip Requejo, Sarah McNitt-Gray, Puja Ruparel, Brent Liu

Proceedings Volume 8319, 83190S (2012) https://doi.org/10.1117/12.911076

KEYWORDS: Video, Motion analysis, Visualization, Data conversion, Video processing, Video coding, Kinematics, Data mining, Information fusion, 3D modeling

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Proceedings Article | 16 February 2012 Paper

Data mining DICOM RT objects for quality control in radiation oncology

Ruchi Deshpande, John DeMarco, Daniel Low, Anh Le, Brent Liu

Proceedings Volume 8319, 83190Q (2012) https://doi.org/10.1117/12.911075

KEYWORDS: Databases, Toxicity, Data mining, Radiation oncology, Rectum, Data modeling, Knowledge discovery, Radiotherapy, Tissues, Computed tomography

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Proceedings Article | 16 February 2012 Paper

A computer-aided detection (CAD) system with a 3D algorithm for small acute intracranial hemorrhage

Ximing Wang, James Fernandez, Ruchi Deshpande, Joon Lee, Tao Chan, Brent Liu

Proceedings Volume 8319, 831913 (2012) https://doi.org/10.1117/12.910958

KEYWORDS: Computer aided design, Algorithm development, Brain, Computer aided diagnosis and therapy, Detection and tracking algorithms, Classification systems, 3D image processing, CAD systems, Control systems, Databases

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Proceedings Article | 25 March 2011 Paper

A solution for archiving and retrieving preclinical molecular imaging data in PACS using a DICOM gateway

Jasper Lee, Bihui Liu, Brent Liu

Proceedings Volume 7967, 796710 (2011) https://doi.org/10.1117/12.877739

KEYWORDS: Picture Archiving and Communication System, Molecular imaging, Preclinical imaging, Data archive systems, Human-machine interfaces, Data conversion, Radiology, Data storage, Standards development, Pre-clinical research

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Proceedings Article | 25 March 2011 Paper

2D vs. 3D mammography observer study

James Reza F. Fernandez, Linda Hovanessian-Larsen, Brent Liu

Proceedings Volume 7967, 79670N (2011) https://doi.org/10.1117/12.878570

KEYWORDS: Mammography, 3D displays, 3D acquisition, Tissues, Breast, 3D image processing, Breast cancer, Cancer, Diagnostics, Digital mammography

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Proceedings Article | 25 March 2011 Paper

Viability of sharing MEG data using minimum-norm imaging

Syed Ashrafulla, Dimitrios Pantazis, John Mosher, Matti Hämäläinen, Brent Liu, Richard Leahy

Proceedings Volume 7967, 79670F (2011) https://doi.org/10.1117/12.879111

KEYWORDS: Magnetoencephalography, Data modeling, Contrast transfer function, Data centers, Statistical analysis, Data analysis, Nerve, Magnetic resonance imaging, Brain mapping, Image segmentation

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Proceedings Article | 25 March 2011 Paper

A multimedia electronic patient record (ePR) system to improve decision support in pre- and rehabilitation through clinical and movement analysis

Brent Liu, Jorge Documet, Sarah McNitt-Gray, Phil Requejo, Jill McNitt-Gray

Proceedings Volume 7967, 79670J (2011) https://doi.org/10.1117/12.878270

KEYWORDS: Data acquisition, Motion analysis, Multimedia, Data modeling, Decision support systems, Imaging systems, Imaging informatics, Data integration, Analytical research, Video

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Proceedings Article | 25 March 2011 Paper

Evaluation of an automatic multiple sclerosis lesion quantification tool in an informatics-based MS e-folder system

Kevin Ma, James Fernandez, Lilyana Amezcua, Alex Lerner, Brent Liu

Proceedings Volume 7967, 79670K (2011) https://doi.org/10.1117/12.878297

KEYWORDS: Computer aided diagnosis and therapy, Computer aided design, Magnetic resonance imaging, Brain, Image segmentation, Neuroimaging, 3D image processing, Detection and tracking algorithms, Databases, Computing systems

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Proceedings Article | 25 March 2011 Paper

Evaluation of a stand-alone computer-aided detection system for acute intra-cranial hemorrhage in emergency environments

James Fernandez, Ruchi Deshpande, Ximing Wang, Brent Liu, Michael Brazaitis, Fletcher Munter, Margaret Liu

Proceedings Volume 7967, 79670H (2011) https://doi.org/10.1117/12.878620

KEYWORDS: Traumatic brain injury, Computer aided diagnosis and therapy, Computer aided design, CAD systems, Algorithm development, Computed tomography, Computing systems, Detection and tracking algorithms, Classification systems

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Proceedings Article | 25 March 2011 Paper

Development of a data mining and imaging informatics display tool for a multiple sclerosis e-folder system

Margaret Liu, Jerry Loo, Kevin Ma, Brent Liu

Proceedings Volume 7967, 796709 (2011) https://doi.org/10.1117/12.878495

KEYWORDS: Computer aided design, Data mining, 3D modeling, Magnetic resonance imaging, Databases, Human-machine interfaces, 3D displays, 3D image processing, Imaging systems, Imaging informatics

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Proceedings Article | 12 March 2010 Paper

A zero-footprint 3D visualization system utilizing mobile display technology for timely evaluation of stroke patients

Young Woo Park, Bing Guo, Monique Mogensen, Kevin Wang, Meng Law, Brent Liu

Proceedings Volume 7628, 76280U (2010) https://doi.org/10.1117/12.845578

KEYWORDS: Display technology, Mobile devices, Computed tomography, Visualization, Radiology, Diagnostics, Medical imaging, 3D visualizations, Brain, Imaging systems

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Proceedings Article | 12 March 2010 Paper

ePR for data grid breast imaging: design and specifications

Jorge Documet, Brent Liu

Proceedings Volume 7628, 76280P (2010) https://doi.org/10.1117/12.845381

KEYWORDS: Breast, Magnetic resonance imaging, Breast imaging, Data storage, Imaging systems, Data archive systems, Computer aided design, Data backup, Breast cancer, Data centers

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Proceedings Article | 12 March 2010 Paper

Data migration and persistence management in a medical imaging informatics data grid

Jasper Lee, Jorge Documet, Brent Liu

Proceedings Volume 7628, 762812 (2010) https://doi.org/10.1117/12.845056

KEYWORDS: Data storage, Imaging informatics, Data archive systems, Databases, Picture Archiving and Communication System, Imaging systems, Data storage servers, Radiology, Data modeling, Medical imaging

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Proceedings Article | 12 March 2010 Paper

A study-centric database model for organizing multimodality images and metadata in animal imaging research facilities

Jasper Lee, Alparslan Gurbuz, Brent Liu

Proceedings Volume 7628, 76280O (2010) https://doi.org/10.1117/12.845050

KEYWORDS: Databases, Data modeling, Animal model studies, Molecular imaging, Preclinical imaging, Imaging systems, Systems modeling, Process modeling, Data archive systems, Data storage

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Proceedings Article | 12 March 2010 Paper

Performance evaluation for volumetric segmentation of multiple sclerosis lesions using MATLAB and computing engine in the graphical processing unit (GPU)

Anh Le, Young Park, Kevin Ma, Colin Jacobs, Brent Liu

Proceedings Volume 7628, 76280W (2010) https://doi.org/10.1117/12.844811

KEYWORDS: Computer aided design, MATLAB, Computer aided diagnosis and therapy, Algorithm development, Image processing, Visualization, Brain, Image segmentation, Magnetic resonance imaging, 3D image processing

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Proceedings Article | 11 March 2010 Paper

Computer-aided bone age assessment for ethnically diverse older children using integrated fuzzy logic system

Kevin Ma, Paymann Moin, Aifeng Zhang, Brent Liu

Proceedings Volume 7628, 76280I (2010) https://doi.org/10.1117/12.844649

KEYWORDS: Bone, Fuzzy logic, Fuzzy systems, Computer aided diagnosis and therapy, Computing systems, System integration, Feature extraction, Computer aided design, CAD systems, Image segmentation

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Proceedings Article | 11 March 2010 Paper

Migration from a prototype ePR for IA-MISS system to alpha version

Jorge Documet, Anh Le, Brent Liu

Proceedings Volume 7628, 76280E (2010) https://doi.org/10.1117/12.845391

KEYWORDS: Surgery, Prototyping, Video, Data acquisition, Data integration, Medical imaging, Data modeling, System integration, Data communications, Databases

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Proceedings Article | 11 March 2010 Paper

An automatic quantification system for MS lesions with integrated DICOM structured reporting (DICOM-SR) for implementation within a clinical environment

Colin Jacobs, Kevin Ma, Paymann Moin, Brent Liu

Proceedings Volume 7628, 76280K (2010) https://doi.org/10.1117/12.844072

KEYWORDS: Image segmentation, Computer aided design, Brain, Computer aided diagnosis and therapy, Imaging systems, Magnetic resonance imaging, Picture Archiving and Communication System, Algorithm development, Neuroimaging, Visualization

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Proceedings Article | 11 March 2010 Paper

Decision support tools for proton therapy ePR: intelligent treatment planning navigator and radiation toxicity tool for evaluating of prostate cancer treatment

Anh Le, Ruchi Deshpande, Brent Liu

Proceedings Volume 7628, 76280F (2010) https://doi.org/10.1117/12.844812

KEYWORDS: Toxicity, Prostate cancer, 3D displays, Prostate, Image processing, Radiation effects, Human-machine interfaces, Rectum, Analytical research, Databases

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Proceedings Article | 11 March 2010 Paper

The development of a disease oriented eFolder for multiple sclerosis decision support

Kevin Ma, Colin Jacobs, James Fernandez, Lilyana Amezcua, Brent Liu

Proceedings Volume 7628, 76280G (2010) https://doi.org/10.1117/12.844690

KEYWORDS: Computer aided design, Databases, Magnetic resonance imaging, Imaging systems, Computer aided diagnosis and therapy, Image segmentation, Human-machine interfaces, Brain, 3D image processing, Information science

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Proceedings Article | 11 March 2010 Paper

Multi-site evaluation of a computer aided detection (CAD) algorithm for small acute intra-cranial hemorrhage and development of a stand-alone CAD system ready for deployment in a clinical environment

Ruchi Deshpande, James Fernandez, Joon Lee, Tao Chan, Brent Liu, H Huang

Proceedings Volume 7628, 76280H (2010) https://doi.org/10.1117/12.844833

KEYWORDS: Algorithm development, Computer aided diagnosis and therapy, Computer aided design, CAD systems, Computed tomography, Image processing, Head, Detection and tracking algorithms, Brain, Computing systems

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Proceedings Article | 13 March 2009 Paper

Evaluation of a computer-aided detection algorithm for timely diagnosis of small acute intracranial hemorrhage on computed tomography in a critical care environment

Joon Lee, Tao Chan, Brent Liu, H. K. Huang

Proceedings Volume 7264, 726416 (2009) https://doi.org/10.1117/12.815390

KEYWORDS: CAD systems, Computer aided design, Computed tomography, Brain, Computer aided diagnosis and therapy, Algorithm development, Detection and tracking algorithms, Image segmentation, Neuroimaging, Head

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Proceedings Article | 13 March 2009 Paper

The development of an MRI lesion quantifying system for multiple sclerosis patients undergoing treatment

Paymann Moin, Kevin Ma, Lilyana Amezcua, Arkadiusz Gertych, Brent Liu

Proceedings Volume 7264, 72640J (2009) https://doi.org/10.1117/12.811947

KEYWORDS: Magnetic resonance imaging, Computer aided design, Image segmentation, Computer aided diagnosis and therapy, Imaging informatics, Image processing, 3D image processing, Algorithm development, Imaging systems, Data modeling

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Proceedings Article | 13 March 2009 Paper

A virtualized infrastructure for molecular imaging research using a data grid model

Jasper Lee, Grant Dagliyan, Brent Liu

Proceedings Volume 7264, 726417 (2009) https://doi.org/10.1117/12.816548

KEYWORDS: Molecular imaging, Data modeling, Data archive systems, Data centers, Preclinical imaging, Databases, Information science, Human-machine interfaces, Data backup, Picture Archiving and Communication System

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Proceedings Article | 13 March 2009 Paper

An online real-time DICOM web-based computer-aided diagnosis system for bone age assessment of children in a PACS environment

Kevin Ma, Aifeng Zhang, Paymann Moin, Mariam Fleshman, Linda Vachon, Brent Liu, H. K. Huang

Proceedings Volume 7264, 726418 (2009) https://doi.org/10.1117/12.816634

KEYWORDS: Computer aided diagnosis and therapy, Bone, Computer aided design, Picture Archiving and Communication System, CAD systems, Databases, Radiology, Human-machine interfaces, Computing systems, Image processing

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Proceedings Article | 13 March 2009 Paper

An image-intensive ePR for image-guided minimally invasive spine surgery applications including real-time intra-operative image acquisition, archival, and display

Jorge Documet, Anh Le, Brent Liu, H. K. Huang, John Chiu

Proceedings Volume 7264, 72640E (2009) https://doi.org/10.1117/12.813610

KEYWORDS: Surgery, Data modeling, Medical imaging, Spine, Data acquisition, Video, Laser therapeutics, Image-guided intervention, Radiology, Imaging informatics

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Proceedings Article | 13 March 2009 Paper

A prototype of image-guided outcome analysis for prostate proton therapy patients based on DICOM-RT ePR

Anh Le, Jorge Documet, Ashley Sullivan, Brent Liu

Proceedings Volume 7264, 72640L (2009) https://doi.org/10.1117/12.813909

KEYWORDS: Imaging systems, Prostate, Prototyping, Image analysis, Prostate cancer, Toxicity, Imaging informatics, Tumors, Data storage, Visualization

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Proceedings Article | 28 February 2009 Paper

Computer-assisted detection (CAD) methodology for early detection of response to pharmaceutical therapy in tuberculosis patients

Robert Lieberman, Heston Kwong, Brent Liu, H. K. Huang

Proceedings Volume 7260, 726030 (2009) https://doi.org/10.1117/12.813583

KEYWORDS: Chest imaging, Lung, Tissues, Computer aided diagnosis and therapy, Chest, Radiography, Image analysis, CAD systems, Statistical analysis, X-ray imaging

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Proceedings Article | 17 March 2008 Paper

Quantitative assessment of multiple sclerosis lesion load using CAD and expert input

Arkadiusz Gertych, Alexis Wong, Alan Sangnil, Brent Liu

Proceedings Volume 6915, 69151U (2008) https://doi.org/10.1117/12.772392

KEYWORDS: Computer aided design, Computer aided diagnosis and therapy, Magnetic resonance imaging, 3D image processing, Brain mapping, Brain, 3D displays, Visualization, Image processing, Image analysis

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Proceedings Article | 13 March 2008 Paper

The workflow and procedures for automatic integration of a computer-aided diagnosis workstation with a clinical PACS with real world examples

Anh Le, Lam Mai, Brent Liu, H. K. Huang

Proceedings Volume 6919, 69190U (2008) https://doi.org/10.1117/12.772990

KEYWORDS: Computer aided design, Picture Archiving and Communication System, Computer aided diagnosis and therapy, Mammography, System integration, Image processing, Chemical vapor deposition, Brain, Medicine, Medical imaging

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Proceedings Article | 13 March 2008 Paper

Assuring image authenticity within a data grid using lossless digital signature embedding and a HIPAA-compliant auditing system

Jasper Lee, Kevin Ma, Brent Liu

Proceedings Volume 6919, 69190O (2008) https://doi.org/10.1117/12.772500

KEYWORDS: Digital imaging, Medical imaging, Databases, Data storage, Computer security, Image processing, Image restoration, Digital image processing, Image storage, Image transmission

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Proceedings Article | 12 March 2008 Paper

Automated bone age assessment of older children using the radius

Sinchai Tsao, Arkadiusz Gertych, Aifeng Zhang, Brent Liu, Han Huang

Proceedings Volume 6919, 69190E (2008) https://doi.org/10.1117/12.770018

KEYWORDS: Bone, Computer aided diagnosis and therapy, Image segmentation, Image processing, Feature extraction, Computer aided design, Fuzzy systems, Fuzzy logic, Information science, Pathology

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Proceedings Article | 12 March 2008 Paper

The design and implementation of decision support tools of proton beam therapy treatment planning of brain cancer patients

Anh Le, Jorge Documet, Anika Joseph, Reinhard Schulte, Brent Liu

Proceedings Volume 6919, 69190G (2008) https://doi.org/10.1117/12.770791

KEYWORDS: Image fusion, Databases, Brain cancer, Imaging systems, Computed tomography, Magnetic resonance imaging, Radiotherapy, Radiology, Visualization, Information science

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Proceedings Article | 12 March 2008 Paper

Web-based computer-aided-diagnosis (CAD) system for bone age assessment (BAA) of children

Aifeng Zhang, Joshua Uyeda, Sinchai Tsao, Kevin Ma, Linda Vachon, Brent Liu, H. K. Huang

Proceedings Volume 6919, 69190H (2008) https://doi.org/10.1117/12.770785

KEYWORDS: Computer aided diagnosis and therapy, Picture Archiving and Communication System, Bone, Computer aided design, Image processing, CAD systems, Chromium, Databases, Computing systems, Radiology

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Proceedings Article | 11 March 2008 Paper

RadSearch: a RIS/PACS integrated query tool

Sinchai Tsao, Jorge Documet, Paymann Moin, Kevin Wang, Brent Liu

Proceedings Volume 6919, 691909 (2008) https://doi.org/10.1117/12.772983

KEYWORDS: Radiology, Picture Archiving and Communication System, Databases, Data mining, Image retrieval, Information science, Medicine, Magnetic resonance imaging, Classification systems, Speaker recognition

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Proceedings Article | 11 March 2008 Paper

A DICOM-RT radiation oncology ePR with decision support utilizing a quantified knowledge base from historical data

Jorge Documet, Brent Liu, Anh Le, Maria Law

Proceedings Volume 6919, 691905 (2008) https://doi.org/10.1117/12.773087

KEYWORDS: Cancer, Radiation oncology, Data mining, Prostate cancer, Oncology, Imaging systems, Radiotherapy, Computed tomography, Information science, Radiology

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Proceedings Article | 11 March 2008 Paper

Integrating DICOM structure reporting (SR) into the medical imaging informatics data grid

Jasper Lee, Anh Le, Brent Liu

Proceedings Volume 6919, 691904 (2008) https://doi.org/10.1117/12.772742

KEYWORDS: Computer aided diagnosis and therapy, Imaging informatics, Databases, Data storage, Medical imaging, Image storage, Image processing, Clinical trials, Computer aided design, Radiology

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Proceedings Article | 30 March 2007 Paper

A CAD system for assessment of MRI findings to track the progression of multiple sclerosis

Alexis Wong, Arkadiusz Gertych, Chi-Shing Zee, Bing Guo, Brent Liu

Proceedings Volume 6514, 65142U (2007) https://doi.org/10.1117/12.709932

KEYWORDS: Image segmentation, Brain, Magnetic resonance imaging, CAD systems, Image analysis, Data modeling, Head, Fuzzy logic, 3D image processing, 3D modeling

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Proceedings Article | 22 March 2007 Paper

Comparison of fingerprint and facial biometric verification technologies for user access and patient identification in a clinical environment

Bing Guo, Yu Zhang, Jorge Documet, Brent Liu, Jasper Lee, Rasu Shrestha, Kevin Wang, H. K. Huang

Proceedings Volume 6516, 65160Y (2007) https://doi.org/10.1117/12.709624

KEYWORDS: Biometrics, Facial recognition systems, Fingerprint recognition, Imaging systems, Sensors, Databases, Medicine, Cameras, Scanners, Signal detection

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