Ms. Danielle Fraser Profile

Danielle Fraser

at McGill Univ

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Proceedings Article | 21 March 2007 Paper

Evaluation of a prototype 3D ultrasound system for multimodality imaging of cervical nodes for adaptive radiation therapy

Danielle Fraser, Palma Fava, Fabio Cury, Te Vuong, Tony Falco, Frank Verhaegen

Proceedings Volume 6509, 65090Y (2007) https://doi.org/10.1117/12.709299

KEYWORDS: Ultrasonography, Computed tomography, Radiotherapy, 3D image processing, Imaging systems, Image fusion, Neck, Cameras, Image registration, Prototyping

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Sonography has good topographic accuracy for superficial lymph node assessment in patients with head and neck cancers. It is therefore an ideal non-invasive tool for precise inter-fraction volumetric analysis of enlarged cervical nodes. In addition, when registered with computed tomography (CT) images, ultrasound information may improve target volume delineation and facilitate image-guided adaptive radiation therapy. A feasibility study was developed to evaluate the use of a prototype ultrasound system capable of three dimensional visualization and multi-modality image fusion for cervical node geometry. A ceiling-mounted optical tracking camera recorded the position and orientation of a transducer in order to synchronize the transducer's position with respect to the room's coordinate system. Tracking systems were installed in both the CT-simulator and radiation therapy treatment rooms. Serial images were collected at the time of treatment planning and at subsequent treatment fractions. Volume reconstruction was performed by generating surfaces around contours. The quality of the spatial reconstruction and semi-automatic segmentation was highly dependent on the system's ability to track the transducer throughout each scan procedure. The ultrasound information provided enhanced soft tissue contrast and facilitated node delineation. Manual segmentation was the preferred method to contour structures due to their sonographic topography.

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