Dr. Kristy K. Brock Profile

Dr. Kristy K. Brock

Assistant Professor at Univ of Texas MD Anderson Cancer Ctr

SPIE Involvement:

Conference Program Committee | Author

Publications (16)

Proceedings Article | 2 April 2024 Presentation + Paper

Feasibility of extracting critical diagnostic imaging report findings following percutaneous liver ablation with a large language model

Alexander Shieh, Iwan Paolucci, Jessica Albuquerque, Kristy Brock, Bruno Odisio

Proceedings Volume 12931, 1293104 (2024) https://doi.org/10.1117/12.3008791

KEYWORDS: Liver, Cancer, Ablation, Tumors, Liver cancer, Abdomen, Radiology

Read Abstract +

Proceedings Article | 29 March 2024 Presentation + Paper

Real-time vasculature segmentation during laparoscopic liver resection using attention-enriched U-Net model in intraoperative ultrasound videos

Muhammad Awais, Mais Altaie, Caleb O'Connor, Austin Castelo, Hop Tran Cao, Kristy Brock

Proceedings Volume 12928, 129280R (2024) https://doi.org/10.1117/12.3008786

KEYWORDS: Ultrasonography, Liver, Image segmentation, Cancer, Deep learning

Read Abstract +

Proceedings Article | 29 March 2024 Poster + Paper

Comprehensive examination of personalized microwave ablation: exploring the effects of blood perfusion rate and metabolic heat on treatment responses

Amirreza Heshmat, Caleb O'Connor, Jun Hong, Jessica Albuquerque Marques Silva, Iwan Paolucci, Aaron Jones, Bruno Odisio, Kristy Brock

Proceedings Volume 12928, 129282A (2024) https://doi.org/10.1117/12.3007856

KEYWORDS: 3D modeling, Liver cancer, Image guided intervention, Finite element methods, Computational modeling

Read Abstract +

Proceedings Article | 7 April 2023 Poster + Paper

Evaluating the feasibility of using reduced scan length for non-contrast CT during image-guided liver ablations

Jun Hong, Erin Snoddy, A. Kyle Jones, Caleb O'Connor, Yuan-Mao Lin, Iwan Paolucci, Bruno Odisio, Kristy Brock

Proceedings Volume 12463, 1246349 (2023) https://doi.org/10.1117/12.2655651

KEYWORDS: Computed tomography, Liver, Ablation, Tumors, Deformation, Biomechanics, Image segmentation, Image registration, Image processing, Cancer

Read Abstract +

Proceedings Article | 3 April 2023 Presentation

Advancing image-guided liver ablation through biomechanical modeling and AI (Conference Presentation)

Kristy Brock

Proceedings Volume 12466, 124660L (2023) https://doi.org/10.1117/12.2664950

Read Abstract +

Proceedings Article | 15 February 2021 Presentation + Paper

Automation of population-based recurrence map for PSMA-PET prostate cancer patients after prostatectomy

Bastien Rigaud, Pascale Béliveau, Guillaume Cazoulat, Daniel Juneau, Cynthia Ménard, Kristy Brock

Proceedings Volume 11596, 115961C (2021) https://doi.org/10.1117/12.2581858

KEYWORDS: Prostate cancer, Veins, Rectum, Bladder, Arteries, Tumor growth modeling, Image segmentation, Image registration, Computed tomography, Cervical cancer

Read Abstract +

Proceedings Article | 17 March 2020 Paper

Towards assessment of histopathology correlation with multiple imaging modalities: A pilot study using a visible mouse

Anando Sen, Charles Kingsley, Jorge de la Cerda, F. William Schuler, Abdallah S. Mohamed, Mark Pagel, Kristy Brock

Proceedings Volume 11317, 113172B (2020) https://doi.org/10.1117/12.2552150

KEYWORDS: Computed tomography, Image registration, Magnetic resonance imaging, 3D image processing, Image segmentation, Tissues, In vivo imaging, Optical coherence tomography, Positron emission tomography, Medical imaging

Read Abstract +

Proceedings Article | 19 March 2018 Paper

Improvement of liver ablation treatment for colorectal liver metastases

Brian Anderson, Ethan Lin, Guillaume Cazoulat, Sanjay Gupta, Bruno Odisio, Kristy Brock

Proceedings Volume 10576, 105762D (2018) https://doi.org/10.1117/12.2294554

KEYWORDS: Liver, Computed tomography, Tumors, Cancer, Colorectal cancer, Image registration, Model-based design, Lawrencium, Error control coding, Oncology

Read Abstract +

Proceedings Article | 21 March 2014 Paper

A hybrid biomechanical intensity based deformable image registration of lung 4DCT

Navid Samavati, Michael Velec, Kristy Brock

Proceedings Volume 9034, 90343J (2014) https://doi.org/10.1117/12.2043560

KEYWORDS: Image registration, Lung, Tumors, Motion models, Finite element methods, Chest, Tissues, Image-guided intervention, Interfaces, Algorithm development

Read Abstract +

Proceedings Article | 27 February 2010 Paper

Demons deformable registration for cone-beam CT guidance: registration of pre- and intra-operative images

S. Nithiananthan, K. Brock, M. Daly, H. Chan, J. Irish, J. Siewerdsen

Proceedings Volume 7625, 76250L (2010) https://doi.org/10.1117/12.845499

KEYWORDS: Image registration, X-ray computed tomography, Imaging systems, Head, Neck, Distortion, Computed tomography, Tissues, Reconstruction algorithms, Detection and tracking algorithms

Read Abstract +

Proceedings Article | 24 February 2010 Paper

Biomechanical based image registration for head and neck radiation treatment

Adil Al-Mayah, Joanne Moseley, Shannon Hunter, Mike Velec, Lily Chau, Stephen Breen, Kristy Brock

Proceedings Volume 7625, 76250M (2010) https://doi.org/10.1117/12.845256

KEYWORDS: Image registration, Tumors, Head, Neck, Radiotherapy, Rigid registration, Computed tomography, 3D modeling, Finite element methods, Cancer

Read Abstract +

Proceedings Article | 13 March 2009 Paper

High-performance intraoperative cone-beam CT on a mobile C-arm: an integrated system for guidance of head and neck surgery

J. Siewerdsen, M. Daly, H. Chan, S. Nithiananthan, N. Hamming, K. Brock, J. Irish

Proceedings Volume 7261, 72610J (2009) https://doi.org/10.1117/12.813747

KEYWORDS: Surgery, Image registration, 3D image processing, Head, Neck, Imaging systems, Endoscopy, Image visualization, 3D acquisition, Video

Read Abstract +

Proceedings Article | 13 March 2009 Paper

Effect of heterogeneous material of the lung on deformable image registration

Adil Al-Mayah, Joanne Moseley, Mike Velec, Kristy Brock

Proceedings Volume 7261, 72610V (2009) https://doi.org/10.1117/12.813828

KEYWORDS: Lung, Motion models, Image registration, Finite element methods, 3D modeling, Tumors, Tissues, Lawrencium, Chest, Mechanics

Read Abstract +

Proceedings Article | 21 March 2007 Paper

Multimode C-arm fluoroscopy, tomosynthesis, and cone-beam CT for image-guided interventions: from proof of principle to patient protocols

J. Siewerdsen, M. Daly, G. Bachar, D. Moseley, G. Bootsma, K. Brock, S. Ansell, G. Wilson, S. Chhabra, D. Jaffray, J. Irish

Proceedings Volume 6510, 65101A (2007) https://doi.org/10.1117/12.713642

KEYWORDS: Surgery, Image-guided intervention, Image quality, Visualization, Imaging systems, Computed tomography, X-ray computed tomography, Head, Sensors, Stereoscopy

Read Abstract +

Proceedings Article | 13 March 2006 Paper

A multi-organ biomechanical model to analyze prostate deformation due to large deformation of the rectum

Kristy Brock, Cynthia Ménard, Jennifer Hensel, David Jaffray

Proceedings Volume 6143, 614312 (2006) https://doi.org/10.1117/12.656646

KEYWORDS: Prostate, Rectum, Image registration, Magnetic resonance imaging, Bladder, Finite element methods, Radiotherapy, Computed tomography, Gold, Natural surfaces

Read Abstract +

Proceedings Article | 14 April 2005 Paper

Nanoengineered multimodal contrast agent for medical image guidance

Gregory Perkins, Jinzi Zheng, Kristy Brock, Christine Allen, David Jaffray

Proceedings Volume 5746, (2005) https://doi.org/10.1117/12.596038

KEYWORDS: Computed tomography, Kidney, Magnetic resonance imaging, In vivo imaging, Iodine, Gadolinium, Liver, Image registration, Medical imaging, Blood

Read Abstract +

Multimodality imaging has gained momentum in radiation therapy planning and image-guided treatment delivery. Specifically, computed tomography (CT) and magnetic resonance (MR) imaging are two complementary imaging modalities often utilized in radiation therapy for visualization of anatomical structures for tumour delineation and accurate registration of image data sets for volumetric dose calculation. The development of a multimodal contrast agent for CT and MR with prolonged in vivo residence time would provide long-lasting spatial and temporal correspondence of the anatomical features of interest, and therefore facilitate multimodal image registration, treatment planning and delivery. The multimodal contrast agent investigated consists of nano-sized stealth liposomes encapsulating conventional iodine and gadolinium-based contrast agents. The average loading achieved was 33.5 ± 7.1 mg/mL of iodine for iohexol and 9.8 ± 2.0 mg/mL of gadolinium for gadoteridol. The average liposome diameter was 46.2 ± 13.5 nm. The system was found to be stable in physiological buffer over a 15-day period, releasing 11.9 ± 1.1% and 11.2 ± 0.9% of the total amounts of iohexol and gadoteridol loaded, respectively. 200 minutes following in vivo administration, the contrast agent maintained a relative contrast enhancement of 81.4 ± 13.05 differential Hounsfield units (ΔHU) in CT (40% decrease from the peak signal value achieved 3 minutes post-injection) and 731.9 ± 144.2 differential signal intensity (ΔSI) in MR (46% decrease from the peak signal value achieved 3 minutes post-injection) in the blood (aorta), a relative contrast enhancement of 38.0 ± 5.1 ΔHU (42% decrease from the peak signal value achieved 3 minutes post-injection) and 178.6 ± 41.4 ΔSI (62% decrease from the peak signal value achieved 3 minutes post-injection) in the liver (parenchyma), a relative contrast enhancement of 9.1 ± 1.7 ΔHU (94% decrease from the peak signal value achieved 3 minutes post-injection) and 461.7 ± 78.1 ΔSI (60% decrease from the peak signal value achieved 5 minutes post-injection) in the kidney (cortex) of a New Zealand white rabbit. This multimodal contrast agent, with prolonged in vivo residence time and imaging efficacy, has the potential to bring about improvements in the fields of medical imaging and radiation therapy, particularly for image registration and guidance.

Showing 5 of 16 publications

Conference Committee Involvement (5)