We present a new method for medical image registration, which is based on the moving least squares (MLS) transformation. Under condition that some of structures should be minimally deformed during registration, our method can offer advantages over other non-rigid registration methods. Our method has been successfully used for medical image registration. The feasibility of the proposed method is demonstrated and compared with the TPS based image registration technique. The experimental results show that the propose method can get better results than the TPS
method.
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