Femtosecond laser pulses in the near-infrared produce visible lesions in the primate eye

Clarence P. Cain; Cynthia A. Toth M.D.; Gary D. Noojin; David J. Stolarski; Benjamin A. Rockwell

doi:10.1117/12.297885

14 January 1998 Femtosecond laser pulses in the near-infrared produce visible lesions in the primate eye

Clarence P. Cain, Cynthia A. Toth M.D., Gary D. Noojin, David J. Stolarski, Benjamin A. Rockwell

Proceedings Volume 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III; (1998) https://doi.org/10.1117/12.297885
Event: BiOS Europe '97, 1997, San Remo, Italy

Abstract

Single pulses in the near-infrared (1060 and 1064 nanometers) were used to measure ophthalmoscopically minimum visible lesion (MVL) thresholds in the rhesus monkey eyes for pulsewidths of 7 nanoseconds (ns), 20 picoseconds (ps), and 150 femtoseconds (fs). MVL thresholds for 1 hour reading and 24 hour reading are reported as the 50% probability for damage (ED₅₀) together with their fiducial limits. These measured thresholds are compared with previously reported thresholds for near-IR and visible wavelengths for the complete range of pulsewidths (ns, ps, and fs). Threshold doses were lower at the 24 hour reading than at the 1 hour reading and both ED₅₀ for the fs pulsewidths were less than 25% of those for ns pulsewidths. MVL thresholds ranged from 19 (mu) J at 7 ns down to 1 (mu) J at 150 fs. Thresholds measured for the nanosecond and picosecond pulsewidths using infrared laser pulses were an order of magnitude larger than for the visible wavelengths at similar pulsewidths while the 150 fs threshold was only about double the value for the 580 nm visible wavelength at 90 fs.

Citation Download Citation

Clarence P. Cain, Cynthia A. Toth M.D., Gary D. Noojin, David J. Stolarski, and Benjamin A. Rockwell "Femtosecond laser pulses in the near-infrared produce visible lesions in the primate eye", Proc. SPIE 3195, Laser-Tissue Interaction, Tissue Optics, and Laser Welding III, (14 January 1998); https://doi.org/10.1117/12.297885

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