Dr. Angelina I. Zherebtsova Profile

Dr. Angelina I. Zherebtsova

Senior Research Fellow at Orel State Univ

SPIE Involvement:

Author

Publications (18)

Proceedings Article | 9 April 2020 Paper

Wearable laser Doppler sensors for evaluating the nutritive and shunt blood flow

Yulia Loktionova, Elena Zharkikh, Evgeny Zherebtsov, Igor Kozlov, Viktor Sidorov, Angelina Zherebtsova, Sergei Sokolovski, Andrey Dunaev, Edik Rafailov

Proceedings Volume 11457, 114570M (2020) https://doi.org/10.1117/12.2564396

KEYWORDS: Blood circulation, Bismuth, Doppler effect, Sensors, Skin, Blood, Signal processing, Medical research, Photonics, Diagnostics

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Proceedings Article | 6 April 2020 Presentation + Paper

Time-frequency analysis and laser Doppler spectrum decomposition to reveal new feature space for diagnosis of diabetes mellitus vascular complications

Igor Kozlov, Evgeny Zherebtsov, Angelina Zherebtsova, Yulia Loktionova, Elena Zharkikh, Andrey Dunaev

Proceedings Volume 11363, 113631I (2020) https://doi.org/10.1117/12.2557035

KEYWORDS: Doppler effect, Blood, Skin, Time-frequency analysis, Diagnostics, Laser Doppler velocimetry, Blood circulation, Capillaries

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Proceedings Article | 2 April 2020 Presentation + Paper

Wearable laser Doppler flowmetry for the analysis of microcirculatory changes during intravenous infusion in patients with diabetes mellitus

Elena Zharkikh, Yulia Loktionova, Igor Kozlov, Angelina Zherebtsova, Victor Sidorov, Evgeny Zherebtsov, Andrey Dunaev, Edik Rafailov

Proceedings Volume 11363, 113631K (2020) https://doi.org/10.1117/12.2552464

KEYWORDS: Doppler effect, Blood circulation, Blood, Skin, Diagnostics, Biomedical optics, Photonics

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Proceedings Article | 22 July 2019 Paper

Analysis of changes in blood flow oscillations under different probe pressure using laser Doppler spectrum decomposition

Igor Kozlov, Evgeny Zherebtsov, Mikhail Mezentsev, Valery Shupletsov, Elena Potapova, Angelina Zherebtsova, Viktor Dremin, Andrey Dunaev, Igor Meglinski

Proceedings Volume 11079, 110791Q (2019) https://doi.org/10.1117/12.2527040

KEYWORDS: Doppler effect, Blood, Blood circulation, Diagnostics, Laser beam diagnostics, Wavelets, Signal processing, Capillaries, Analytical research

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Proceedings Article | 22 July 2019 Paper

Wearable sensor system for multipoint measurements of blood perfusion: pilot studies in patients with diabetes mellitus

Evgeny Zherebtsov, Elena Zharkikh, Igor Kozlov, Yulia Loktionova, Angelina Zherebtsova, Ilya Rafailov, Sergei Sokolovski, Victor Sidorov, Andrey Dunaev, Edik Rafailov

Proceedings Volume 11079, 110791O (2019) https://doi.org/10.1117/12.2526966

KEYWORDS: Blood, Sensors, Doppler effect, Diagnostics, Blood circulation, Electronic components, Medicine, Capillaries, Control systems

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Proceedings Article | 22 July 2019 Paper

Studies of age-related changes in blood perfusion coherence using wearable blood perfusion sensor system

Yulia Loktionova, Evgeny Zherebtsov, Elena Zharkikh, Igor Kozlov, Angelina Zherebtsova, Victor Sidorov, Sergei Sokolovski, Ilya Rafailov, Andrey Dunaev, Edik Rafailov

Proceedings Volume 11075, 1107507 (2019) https://doi.org/10.1117/12.2526967

KEYWORDS: Blood, Wavelets, Blood circulation, Signal detection, Sensors, Doppler effect, Cardiovascular system, Pathology, Photonics, Diagnostics

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Proceedings Article | 3 June 2019 Paper

Pilot studies of age-related changes in blood perfusion in two different types of skin

Yulia Loktionova, Elena Zharkikh, Igor Kozlov, Evgeny Zherebtsov, Svetlana Bryanskaya, Angelina Zherebtsova, Victor Sidorov, Sergei Sokolovski, Andrey Dunaev, Edik Rafailov

Proceedings Volume 11065, 110650S (2019) https://doi.org/10.1117/12.2522968

KEYWORDS: Blood circulation, Doppler effect, Diagnostics, Pathology, Cardiovascular system

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Proceedings Article | 1 March 2019 Presentation + Paper

Novel wearable VCSEL-based sensors for multipoint measurements of blood perfusion

Evgeny Zherebtsov, Elena Zharkikh, Igor Kozlov, Angelina Zherebtsova, Yulia Loktionova, Nikolay Chichkov, Ilya Rafailov, Victor Sidorov, Sergei Sokolovski, Andrey Dunaev, Edik Rafailov

Proceedings Volume 10877, 1087708 (2019) https://doi.org/10.1117/12.2509578

KEYWORDS: Blood, Doppler effect, Blood circulation, Laser scattering, Skin, Tissues, Measurement devices, Photonics, Vertical cavity surface emitting lasers, Smart sensors

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Proceedings Article | 17 May 2018 Paper

Laser doppler spectrum decomposition applied in diagnostics of microcirculatory disturbances

Igor Kozlov, Evgeny Zherebtsov, Victor Dremin, Angelina Zherebtsova, Elena Zharkikh, Andrey Dunaev, Edik Rafailov

Proceedings Volume 10685, 106854O (2018) https://doi.org/10.1117/12.2289551

KEYWORDS: Doppler effect, Doppler tomography, Blood, Skin, Diagnostics, Signal processing, Wavelets, Blood circulation, Analytical research, Lymphatic system

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Proceedings Article | 17 May 2018 Paper

Evaluation of microvascular disturbances in rheumatic diseases by analysis of skin blood flow oscillations

Irina Makovik, Viktor Dremin, Angelina Zherebtsova, Alexander Krupatkin, Lyudmila Khakhicheva, Vadim Muradyan, Igor Meglinski, Andrey Dunaev

Proceedings Volume 10685, 106854S (2018) https://doi.org/10.1117/12.2288239

KEYWORDS: Diagnostics

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Proceedings Article | 26 February 2018 Paper

Fibre optic probe for fluorescence diagnostics with blood influence compensation

Evgeny Zherebtsov, Viktor Dremin, Elena Zharkikh, Angelina Zherebtsova, Ilya Rafailov, Andrey Dunaev, Natalia Bazieva, Edik Rafailov

Proceedings Volume 10493, 104931L (2018) https://doi.org/10.1117/12.2290431

KEYWORDS: Blood, Luminescence, Skin, Diffuse reflectance spectroscopy, Tissue optics, Diagnostics, Monte Carlo methods, Absorption, In vivo imaging, Neural networks

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SPIE Journal Paper | 19 August 2017 Open Access

Multimodal optical measurement for study of lower limb tissue viability in patients with diabetes mellitus

Viktor Dremin, Evgeny Zherebtsov, Victor Sidorov, Alexander Krupatkin, Irina Makovik, Angelina Zherebtsova, Elena Zharkikh, Elena V. Potapova, Andrey Dunaev, Alexander Doronin, Alexander Bykov, Ilya Rafailov, Karina Litvinova, Sergei Sokolovski, Edik Rafailov

JBO, Vol. 22, Issue 08, 085003, (August 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.8.085003

KEYWORDS: Luminescence, Skin, Diagnostics, Tissues, Tissue optics, Blood, Optical fibers, Optical testing, Doppler effect, Blood circulation

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SPIE Journal Paper | 11 April 2017 Open Access

Combined use of laser Doppler flowmetry and skin thermometry for functional diagnostics of intradermal finger vessels

Evgeny Zherebtsov, Angelina Zherebtsova, Alexander Doronin, Andrey Dunaev, Konstantin Podmasteryev, Alexander Bykov, Igor Meglinski

JBO, Vol. 22, Issue 04, 040502, (April 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.4.040502

KEYWORDS: Skin, Diagnostics, Temperature metrology, Blood, Thermometry, Blood circulation, Doppler effect, Doppler tomography, Capillaries, Tissue optics

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Proceedings Article | 24 March 2017 Paper

Non-invasive control of influence of polyethylene glycol on transport function of fluorescent colored liposomal nanoparticles

O. Stelmashchuk, E. Zherebtsov, A. Zherebtsova, E. Kuznetsova, A. Vinokurov, A. Dunaev, A. Mamoshin, I. Snimshchikova, A. Borsukov, A. Bykov, I. Meglinski

Proceedings Volume 10336, 1033604 (2017) https://doi.org/10.1117/12.2269379

KEYWORDS: Nanoparticles, Fluorescent markers, Fluorescence spectroscopy, Luminescence, Diagnostics, Fiber lasers, Tissues, Particles, Animal model studies, Medicine

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Proceedings Article | 24 March 2017 Paper

The influence of local pressure on evaluation parameters of skin blood perfusion and fluorescence

E. Zherebtsov, K. Kandurova, E. Seryogina, I. Kozlov, V. Dremin, A. Zherebtsova, A. Dunaev, I. Meglinski

Proceedings Volume 10336, 1033608 (2017) https://doi.org/10.1117/12.2267957

KEYWORDS: Blood, Skin, Luminescence, Diagnostics, Doppler effect, Fluorescence spectroscopy, Tissue optics, Absorption, Blood circulation, Biomedical optics

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Proceedings Article | 21 April 2016 Paper

The development of attenuation compensation models of fluorescence spectroscopy signals

Victor Dremin, Evgeny Zherebtsov, Ilya Rafailov, Andrey Vinokurov, Irina Novikova, Angelina Zherebtsova, Karina Litvinova, Andrey Dunaev

Proceedings Volume 9917, 99170Y (2016) https://doi.org/10.1117/12.2229451

KEYWORDS: 3D modeling, Signal attenuation, Fluorescence spectroscopy, Laser spectroscopy, Doppler effect, Monte Carlo methods, Diffuse reflectance spectroscopy, Luminescence, Tissues, Blood, Absorption, Blood circulation, Tissue optics

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Proceedings Article | 21 April 2016 Paper

Study of the functional state of peripheral vessels in fingers of rheumatological patients by means of laser Doppler flowmetry and cutaneous thermometry measurements

Angelina Zherebtsova, Evgeny Zherebtsov, Andrey Dunaev, Konstantin Podmasteryev, Olga Pilipenko, Alexander Krupatkin, Lyudmila Khakhicheva, Vadim Muradyan

Proceedings Volume 9917, 99170M (2016) https://doi.org/10.1117/12.2229827

KEYWORDS: Doppler effect, Thermometry, Diagnostics, Skin, Thermography, Blood, Blood circulation, Temperature metrology, Laser development, Pathology

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Vasospastic disorders are a common class of rheumatic disease. These include syndromes such as vegetative dystonia, Raynaud's syndrome, vibration disease and rheumatoid arthritis among others. The aim of this work is to develop an original method of diagnosing the functional state of peripheral vessels of the fingers, based on the simultaneous recording of LDF- and thermograms during the occlusion test, for determining vascular disorders of rheumatological patients.

A diagnostic method was developed for assessing the functional state of the peripheral vessels of fingers, based on carrying out occlusion test in a thermally stabilized environment, with simultaneous recording of signals of laser Doppler flowmetry and skin thermometry. To verify the diagnostic value of the proposed method, a series of experiments were carried out on 41 rheumatological patients: 5 male and 36 females (average age 56.0±12.2 years). The most common diagnoses in the patient group were rheumatoid arthritis, arthrosis, gout and systemic lupus erythematosus. The laser analyser of blood microcirculation “LAKK-02” (SPE “LAZMA” Ltd, Russia) and a custom developed multi-channel thermometry device for low inertia thermometry were used for experimental measurements. The measurements of cutaneous temperature and the index of microcirculation were performed on the distal phalanx of the third finger of the right hand. Occlusion tests were performed with water baths at 25 and 42 °C and a tonometer cuff with a pressure of 200-220 mmHg for 3 min on the upper arm.

The results of experimental studies are presented and interpreted. These data indicate a violation of the blood supply regulation in the form of a pronounced tendency towards microvascular vasoconstriction in the fingers. Thus, the response displaying a tendency toward angiospasm among patients in the rheumatological diseases profile group was observed mainly in the most severe cases (49 % of this group). The prospects of the developed diagnostic method of microcirculatory disorders in rheumatic diseases are evaluated. Thus, cutaneous blood microcirculation and temperature measurements performed together can help in diagnosis of the functional state of peripheral vessels both in a healthy state and when expressing pathology.

Proceedings Article | 7 March 2016 Presentation + Paper

The blood perfusion and NADH/FAD content combined analysis in patients with diabetes foot

Victor Dremin, Victor Sidorov, Alexander Krupatkin, Gagik Galstyan, Irina Novikova, Angelina Zherebtsova, Evgeny Zherebtsov, Andrey Dunaev, Zera Abdulvapova, Karina Litvinova, Ilya Rafailov, Sergei Sokolovski, Edik Rafailov

Proceedings Volume 9698, 969810 (2016) https://doi.org/10.1117/12.2212758

KEYWORDS: Blood circulation, Tissues, Fluorescence spectroscopy, Doppler effect, Metabolism, Laser spectroscopy, Luminescence, Optical fibers, Diagnostics, Blood, Skin, Mode conditioning cables, Tissue optics, Oxygen

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Showing 5 of 18 publications

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