Prof. Conor L. Evans Profile

Prof. Conor L. Evans

Assistant Professor at Wellman Ctr for Photomedicine

SPIE Involvement:

Conference Chair | Conference Program Committee | Editorial Board Member: Biophotonics Discovery | Editor | Author

Publications (63)

Proceedings Article | 13 March 2024 Presentation

Visualizing and quantifying drug distribution in tissue

Conor Evans

Proceedings Volume PC12821, PC1282101 (2024) https://doi.org/10.1117/12.3007492

KEYWORDS: Visualization, Tissues

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Proceedings Article | 13 March 2024 Presentation

Dual modality monitoring of topical formulations within human skin using stimulated Raman scattering (SRS) microscope

Dandan Tu, Nick-Sidney Lemberger, Kristin Wallmeier, Jackson Riseman, Benjamin Kuzma, Yuxiao Wei, Ting Chean Khoo, Priyanka Ghosh, Sam Raney, Markham Luke, Carsten Fallnich, Conor Evans

Proceedings Volume PC12821, PC1282104 (2024) https://doi.org/10.1117/12.3001122

KEYWORDS: Skin, Raman scattering, Near infrared, Microscopes, Signal intensity, Light scattering, Tissue optics, Temporal resolution, Signal attenuation, Photons

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Proceedings Article | 13 March 2024 Presentation

Quantitative analysis of drug tablet aging by sparse spectral sampling stimulated Raman scattering microscopy

Yuxiao Wei, Isaac Pence, Conor Evans

Proceedings Volume PC12855, PC1285518 (2024) https://doi.org/10.1117/12.3001041

KEYWORDS: Tablets, Raman scattering, Quantitative analysis, Microscopy, Spatial resolution, Solid state electronics, Quality control, Imaging spectroscopy, Chemical analysis, Visual inspection

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Proceedings Article | 13 March 2024 Presentation

Fast hyperspectral SRS for analysis of drug tablet formulation

Yuxiao Wei, Isaac Pence, Conor Evans

Proceedings Volume PC12821, PC128210C (2024) https://doi.org/10.1117/12.3001829

KEYWORDS: Tablets, Raman scattering, Visualization, Solids, Microscopy, Spatial resolution, Solid state electronics, Quality control, Imaging spectroscopy, Chemical analysis

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Proceedings Article | 11 August 2023 Paper

New models of innovation through collaboration: the translation journey of novel concepts in corneal refractive surgery

Lara Buhl, Maron Dolling, Ying Wang, Badri Parshad, Xiaolei Li, Christian Wertheimer, Stefan Kassumeh, Siegfried Priglinger, Mark Bischoff, Conor Evans, R. Rox Anderson, Reginald Birngruber, Gabriela Apiou-Sbirlea

Proceedings Volume 12627, 126270P (2023) https://doi.org/10.1117/12.2687846

KEYWORDS: Surgery, Biomedical optics, Medical research, Cornea, Industry, Photomedicine, Ophthalmology, Medicine, Translational research

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Proceedings Article | 17 March 2023 Presentation

Evaluating cutaneous pharmacokinetics of tazarotene by coherent Raman imaging

Maria Alice Maciel Tabosa, Conor Evans, Saara Luna

Proceedings Volume 12357, 123570A (2023) https://doi.org/10.1117/12.2647609

KEYWORDS: Coherence imaging, Skin, Raman spectroscopy, In vivo imaging, Ear, Visualization, Spectroscopy, Quantitative analysis, Imaging spectroscopy, Image processing

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Proceedings Article | 17 March 2023 Presentation

Visualizing and quantifying drugs in tissue

Conor Evans

Proceedings Volume 12357, 1235702 (2023) https://doi.org/10.1117/12.2653144

KEYWORDS: Visualization, Tissues

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Proceedings Article | 17 March 2023 Presentation

Stimulated Raman scattering (SRS) microscopy and deep learning: a novel pharmacokinetic approach for evaluation of topical bioequivalence

Fotis Iliopoulos, Isaac Pence, Priyanka Ghosh, Sam Raney, Markham Luke, Conor Evans

Proceedings Volume 12357, 1235706 (2023) https://doi.org/10.1117/12.2649179

KEYWORDS: Skin, Raman scattering, Microscopy, Tissues, Real time imaging, Plasma

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Proceedings Article | 15 March 2023 Presentation

Cutaneous pharmacokinetic and pharmacodynamic imaging with coherent Raman scattering (Conference Presentation)

Conor Evans

Proceedings Volume PC12392, PC123920X (2023) https://doi.org/10.1117/12.2647916

KEYWORDS: Coherence imaging, Skin, Raman scattering, Raman spectroscopy, In vitro testing, Visualization, Scatter measurement, Machine learning, In vivo imaging, Drug discovery

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Proceedings Article | 14 March 2023 Presentation

Optical sensors for versatile carbon dioxide monitoring devices (Conference Presentation)

Xiaolei Li, Juan Pedro Cascales, Emmanuel Roussakis, Conor Evans

Proceedings Volume 12417, 124170R (2023) https://doi.org/10.1117/12.2650156

KEYWORDS: Carbon dioxide, Optical sensors, Optical components, Tissue optics, Skin, Sensing systems, Remote sensing, Reliability, Polymers, Polymer thin films

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Proceedings Article | 6 March 2023 Presentation

A phosphorescent microneedle array for measurement of oxygen partial pressure in tissue

Matthias Müller, Juan Pedro Cascales Sandoval, Haley Marks, Michael Wang-Evers, Dieter Manstein, Conor Evans

Proceedings Volume PC12375, PC1237505 (2023) https://doi.org/10.1117/12.2649485

KEYWORDS: Oxygen, Tissues, Skin, Phosphorescence, Blood, Tissue optics, Oximetry, Ischemia, Heart, Electrodes

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Proceedings Article | 6 March 2023 Presentation

Innovations and new applications of a wearable device for remote monitoring of transcutaneous tissue oxygenation

Daniel Greenfield, Juan Cascales Sandoval, Conor Evans

Proceedings Volume PC12375, PC1237504 (2023) https://doi.org/10.1117/12.2649467

KEYWORDS: Tissues, Oxygen, Phosphorescence, Microcontrollers, Instrument modeling, Heart, Data modeling, Tissue optics, Standards development, Photoplethysmography

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Proceedings Article | 6 March 2023 Presentation

Transcutaneous monitoring of oxygen and carbon dioxide using wearable devices

Juan Pedro Cascales Sandoval, Emmanuel Roussakis, Xiaolei Li, Daniel Greenfield, Lilian Witthauer, Avery Goss, Helen Keshishian, John Nguyen, Haley Marks, Adina Draghici, Jason Hamner, J. Taylor, Conor Evans

Proceedings Volume PC12375, PC1237503 (2023) https://doi.org/10.1117/12.2649855

KEYWORDS: Oxygen, Carbon dioxide, Blood circulation, Tissues, Skin, Sensors, Prototyping, Polymers, Phosphorescence, Natural surfaces

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Proceedings Article | 7 March 2022 Presentation

Cutaneous pharmacokinetics of escalating Ruxolitinib formulation doses utilizing a coherent Raman imaging pipeline

Benjamin Kuzma, Thomas Würthwein, Nick Lemberger, Kristin Wallmeier, Carsten Fallnich, Conor Evans

Proceedings Volume PC11938, PC1193808 (2022) https://doi.org/10.1117/12.2608845

KEYWORDS: Coherence imaging, Raman spectroscopy, Tissues, Ear, Skin

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Proceedings Article | 7 March 2022 Presentation

Applying sparse spectral sampling SRS microscopy to evaluate topical pharmacokinetics

Isaac Pence, Benjamin Kuzma, Conor Evans

Proceedings Volume PC11938, PC119380E (2022) https://doi.org/10.1117/12.2608810

KEYWORDS: Microscopy, Raman spectroscopy, Ultrafast imaging, Tissues, Skin, Raman scattering, Optical parametric oscillators, Nondestructive evaluation, Light sources, Imaging spectroscopy

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Proceedings Article | 7 March 2022 Presentation

The earlier the better: instantaneous cutaneous concentration quantification at the time of application

Avery Goss, Benjamin Kuzma, Conor Evans

Proceedings Volume PC11938, PC119380C (2022) https://doi.org/10.1117/12.2608673

KEYWORDS: Skin, In vitro testing, Coherence imaging, Tissues, Temporal resolution, Raman spectroscopy, Ear, 3D acquisition

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Proceedings Article | 7 March 2022 Presentation

Wearable device and methods for non-invasive measurements of tissue oxygenation

Juan Pedro Cascales Sandoval, Daniel Greenfield, Emmanuel Roussakis, Xiaolei Li, Avery Goss, Lilian Witthauer, Liv Kelley, Conor Evans

Proceedings Volume PC11956, PC1195603 (2022) https://doi.org/10.1117/12.2609177

KEYWORDS: Tissues, Oxygen, Skin, Instrument modeling, Blood circulation, Algorithm development, Wound healing, Tissue optics, Temperature metrology, Sensors

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Proceedings Article | 2 March 2022 Presentation

Quantifying pharmacodynamics in a mouse inflammation model via CARS and SRS imaging paired with machine learning analysis

Daniel Greenfield, Conor Evans

Proceedings Volume PC11973, PC1197308 (2022) https://doi.org/10.1117/12.2608687

KEYWORDS: Ear, Inflammation, CARS tomography, Machine learning, Visualization, Mouse models, Diagnostics, Convolutional neural networks

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Proceedings Article | 2 March 2022 Presentation

Dynamic imaging of pharmacokinetics with Sparse Spectral Sampling Stimulated Raman Scattering (S4RS) hyperspectral microscopy

Conor Evans, Isaac Pence, Benjamin Kuzma

Proceedings Volume PC11973, PC1197303 (2022) https://doi.org/10.1117/12.2608880

KEYWORDS: Raman scattering, Microscopy, Raman spectroscopy, Imaging systems, Hyperspectral imaging, Molecules, Microscopes, Visualization, Tissues, Optical parametric oscillators

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Proceedings Article | 7 March 2021 Presentation

Deep learning based quantification of cutaneous drug uptake from standard epi-fluorescence microscopy

Conor Evans, Maiko Hermsmeier, Kin Chan

Proceedings Volume 11624, 116240J (2021) https://doi.org/10.1117/12.2577350

KEYWORDS: Skin, Microscopy, Luminescence, Fluorescence lifetime imaging, Tissues, Neural networks, Convolutional neural networks

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Proceedings Article | 5 March 2021 Presentation

Pharmacokinetic and pharmacodynamic tomography

Conor Evans

Proceedings Volume 11624, 1162404 (2021) https://doi.org/10.1117/12.2587224

KEYWORDS: Tomography, Visualization, Tissues

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Proceedings Article | 5 March 2021 Presentation

Welcome and Introduction to SPIE Conference 11624

Conor Evans, Kin Chan

Proceedings Volume 11624, 1162402 (2021) https://doi.org/10.1117/12.2593324

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Proceedings Article | 5 March 2021 Presentation

Quantifying human cutaneous pharmacokinetics

Conor Evans

Proceedings Volume 11656, 1165608 (2021) https://doi.org/10.1117/12.2577713

KEYWORDS: Coherence imaging, Skin, Raman spectroscopy, Chromium, Tissues, Visualization, Raman scattering, Machine learning, Image processing, Diffusion

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Proceedings Article | 5 March 2021 Presentation

Oxygen sensing tools for the improved assessment of hypoxia-related conditions

Lilian Witthauer, Juan Pedro Cascales, Emmanuel Roussakis, Avery Goss, Yenyu Chen, Xiaolei Li, Conor Evans

Proceedings Volume 11635, 116350C (2021) https://doi.org/10.1117/12.2576935

KEYWORDS: Oxygen, Tissues, Injuries, Hypoxia, Vascular diseases, Phosphorescence, Optoelectronics, In vivo imaging, Cancer, Blood circulation

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Proceedings Article | 5 March 2021 Presentation

Wearable device for remote monitoring of transcutaneous tissue oxygenation

Juan Pedro Cascales Sandoval, Emmanuel Roussakis, Lilian Witthauer, Avery Goss, Xiaolei Li, Daniel Greenfield, Yenyu Chen, Haley Marks, Conor Evans

Proceedings Volume 11638, 116380C (2021) https://doi.org/10.1117/12.2577048

KEYWORDS: Tissues, Oxygen, Tissue optics, Calibration, Blood, Temperature metrology, Skin, Prototyping, Precision calibration, Phosphorescence

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Proceedings Article | 20 April 2020 Presentation

Vaccine visualization using a zwitterionic near-infrared fluorophore (Conference Presentation)

Wataru Katagiri, Marc-André Tetrault, Homan Kang, Sinyoung Jeong, Conor Evans, Hak Soo Choi, Satoshi Kashiwagi

Proceedings Volume 11219, 1121906 (2020) https://doi.org/10.1117/12.2545297

KEYWORDS: Visualization, Near infrared, Lymphatic system, In vivo imaging, Silica, Nanoparticles, Absorbance, Imaging systems, Flow cytometry, Safety

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Proceedings Article | 10 March 2020 Presentation

Quasi-simultaneous coherent Raman imaging of components in the fingerprint, silent and high-wavenumber region with a portable all-fiber light source (Conference Presentation)

Maximilian Brinkmann, Tim Hellwig, Isaac Pence, Conor Evans, Carsten Fallnich

Proceedings Volume 11252, 112521G (2020) https://doi.org/10.1117/12.2546094

KEYWORDS: Coherence imaging, Light sources, Raman spectroscopy, Visualization, Switching, Wavelength tuning, Diagnostics, Laser amplifiers, Image acquisition, Ear

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Proceedings Article | 10 March 2020 Presentation

Highly sensitive and reliable plasmonic nanoparticle-based digital cytometry for quantification of MUC16 binding on the surface of leukocytes (Conference Presentation)

Sinyoung Jeong, Germán González, Nicholas Nowell, Lauren Austin, Jawad Hoballah, Fatima Mubarak, Arvinder Kapur, Manish Patankar, Daniel Cramer, Petra Krauledat, W. Peter Hansen, Conor Evans

Proceedings Volume 11254, 112540R (2020) https://doi.org/10.1117/12.2545088

KEYWORDS: Plasmonics, Ovarian cancer, Gold, Nanoparticles, Cancer, Pathogens, Tumors, Molecules, Blood, Monoclonal antibodies

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Proceedings Article | 10 March 2020 Presentation

A luminescent oxygen-sensing hydrogel for mapping tissue oxygenation (Conference Presentation)

Haley Marks, Juan Pedro Cascales Sandoval, Joshua Glahn, Katherine Cook, Emmanuel Roussakis, Mark Grinstaff, Dieter Manstein, Conor Evans

Proceedings Volume 11256, 112560F (2020) https://doi.org/10.1117/12.2544561

KEYWORDS: Tissues, Oxygen, Skin, Lead, Imaging devices, Absorbance, Imaging systems, Molecules, Quantum efficiency, Visualization

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Proceedings Article | 13 March 2019 Presentation

A luminescent oxygen-sensing hydrogel for open wounds (Conference Presentation)

Haley Marks, Emmanuel Roussakis, Katherine Cook, Mark Grinstaff, Gabriela Apiou-Sbirlea, Conor Evans

Proceedings Volume 10893, 108930M (2019) https://doi.org/10.1117/12.2507486

KEYWORDS: Oxygen, Skin, Visualization, Phosphorescence, Wound healing, Tissues, Blood oxygen saturation, Calibration, Electrodes, Molecules

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Proceedings Article | 5 March 2019 Paper

Multimodal microscopy toolkit for visualizing multicomponent topical drug formulations in humans

Alexander Fast, Sinyoung Jeong, Maiko Hermsmeier, Akira Yamamoto, Xin Chen, Kin Chan, Conor Evans

Proceedings Volume 10882, 108822J (2019) https://doi.org/10.1117/12.2510157

KEYWORDS: Tissues, Fluorescence lifetime imaging, Visualization, Skin, Raman spectroscopy, Microscopy, Confocal microscopy, Absorption, Multiphoton tomography, Natural surfaces

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Proceedings Article | 4 March 2019 Presentation

Fluorescence lifetime imaging microscopy along with non-Euclidean phasor analysis for visualization of drug distribution of a topical drug in human facial skin (Conference Presentation)

Sinyoung Jeong, Alexander Fast, Sam Osseiran, Maiko Hermsmeier, Tanvee Sawant, Kin Chan, Conor Evans

Proceedings Volume 10859, 1085908 (2019) https://doi.org/10.1117/12.2510218

KEYWORDS: Skin, Visualization, Fluorescence lifetime imaging, Visual analytics, Microscopy, Luminescence

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SPIE Journal Paper | 12 February 2019 Open Access

Sensing, monitoring, and release of therapeutics: the translational journey of next generation bandages (Erratum)

Zongxi Li, Haley Marks, Conor Evans, Gabriela Apiou-Sbirlea

JBO, Vol. 24, Issue 02, 029802, (February 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.2.029802

KEYWORDS: Lithium, Biomedical optics, Medical research, Photomedicine, Intellectual property, Liquids, Calibration, Tissue optics, Skin, Inflammation

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SPIE Journal Paper | 27 December 2018 Open Access

Sensing, monitoring, and release of therapeutics: the translational journey of next generation bandages

Zongxi Li, Haley Marks, Conor L. Evans, Gabriela Apiou-Sbirlea

JBO, Vol. 24, Issue 02, 021201, (December 2018) https://doi.org/10.1117/12.10.1117/1.JBO.24.2.021201

KEYWORDS: Oxygen, Tissues, Skin, Cameras, Prototyping, Biomedical optics, Surgery, Sensors, Phosphorescence, Optical filters

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Proceedings Article | 5 April 2018 Presentation

An oxygen-sensing phosphorescent liquid bandage for post-operative flap monitoring (Conference Presentation)

Haley Marks, Emmanuel Roussakis, Nicholas Nowell, Alexandra Bucknor, Parisa Kamali, Samuel Lin, Conor Evans

Proceedings Volume 10484, 104840F (2018) https://doi.org/10.1117/12.2290829

KEYWORDS: Tissue optics, Liquids, Phosphorescence, Oxygen, Surgery, Skin, Visualization, Oximetry, Diagnostics, Cancer

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