Prof. Jessica C. Ramella-Roman Profile

Prof. Jessica C. Ramella-Roman

at Florida International Univ

SPIE Involvement:

Conference Chair | Conference Program Committee | Track Chair | Editorial Board Member: Journal of Biomedical Optics | Author | Editor | Student Chapter Advisor | Special Event Speaker

Publications (110)

SPIE Journal Paper | 30 May 2024 Open Access

Open Access

Special Section Guest Editorial: Polarimetry in Biomedical Optics

Alex Vitkin, Jessica Ramella-Roman, Nirmalya Ghosh

JBO, Vol. 29, Issue 05, 052901, (May 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.5.052901

KEYWORDS: Polarimetry, Biomedical optics, Polarized light, Polarization, Tissues, Biomedical applications, Pathology, Microscopy, Medical research, Imaging systems

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Proceedings Article | 13 March 2024 Presentation

Presentation

Investigation of pregnant mice cervix remodeling with a self validating Mueller matrix micro-mesoscope (SAMMM)

JunZhu Pei, Jessica Ramella-Roman, Ajmal Ajmal, Tananant Boonya-Ananta

Proceedings Volume PC12845, PC1284507 (2024) https://doi.org/10.1117/12.3005362

KEYWORDS: Cervix, Mueller matrices, Visualization, Risk assessment, Neurological disorders, Medicine, Brain-machine interfaces

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Proceedings Article | 13 March 2024 Presentation

Presentation

Depth-resolved Mueller matrix analysis of cervical remodeling in pregnant mice

Ajmal Ajmal, JunZhu Pei, Amanda Sanchez, Jessica Ramella-Roman

Proceedings Volume PC12845, PC1284508 (2024) https://doi.org/10.1117/12.3005367

KEYWORDS: Mueller matrices, Cervix, Polarization imaging, Polarization, Collagen, Tissues, Tissue optics, Statistical analysis, Reflection, Polarimetry

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Proceedings Article | 13 March 2024 Presentation

Presentation

The development of a dynamic phantom for PPG signal validation with skin tone and obesity variations

Mel Tananant Boonya-Ananta, Andres Rodriguez, Ajmal Ajmal, Eddie Baute, Ernesto Rodriguez, Marianne Porras Bouzas, Jessica Ramella-Roman

Proceedings Volume PC12833, PC1283306 (2024) https://doi.org/10.1117/12.3005473

KEYWORDS: Skin, Arteries, Optical properties, Rapid manufacturing, Point-of-care devices, Photoplethysmography, Oximeters, Optical components, Interfaces, Fluid dynamics

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SPIE Journal Paper | 27 January 2024 Open Access

Open Access

Speculum-free portable preterm imaging system

Tananant Boonya-ananta, Mariacarla Gonzalez, Ajmal Ajmal, Vinh Nguyen Du Le, Edward DeHoog, Michael Paidas, Arumugam Jayakumar, Jessica Ramella-Roman

JBO, Vol. 29, Issue 05, 052918, (January 2024) https://doi.org/10.1117/12.10.1117/1.JBO.29.5.052918

KEYWORDS: Imaging systems, Polarization, Portability, Cervix, Cameras, Silicon, Design, Light emitting diodes, Depolarization, Light sources and illumination

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Proceedings Article | 3 October 2023 Presentation + Paper

Presentation + Paper

Complete Mueller polarimetry: do we need it for biological tissues diagnosis?

Tatiana Novikova, Jessica Ramella-Roman, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Omar Rodríguez-Núñez, Irena Zubak, Philippe Schucht

Proceedings Volume 12690, 1269006 (2023) https://doi.org/10.1117/12.2689662

KEYWORDS: Mueller matrices, Polarimetry, Depolarization, Brain, Tissues, Neuroimaging, Diagnostics, Reflection, Nervous system

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Proceedings Article | 11 August 2023 Paper

Paper

Partial Mueller polarimetry for the complete optical diagnosis of biological tissue

Tatiana Novikova, Jessica Ramella-Roman, Leonard Felger, Romain Gros, Ekkehard Hewer, Theoni Maragkou, Richard McKinley, Stefano Moriconi, Michael Murek, Angelo Pierangelo, Omar Rodríguez-Núñez, Irena Zubak, Philippe Schucht

Proceedings Volume 12629, 1262902 (2023) https://doi.org/10.1117/12.2670094

KEYWORDS: Polarimetry, Tissues, Tissue optics, Mueller matrices, Biomedical optics, Polarization, Depolarization, Optical components, Imaging systems, Video

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Proceedings Article | 12 April 2023 Presentation

Presentation

TBD I

Jessica Ramella-Roman

Proceedings Volume PC12382, PC1238201 (2023) https://doi.org/10.1117/12.2659747

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Proceedings Article | 30 March 2023 Presentation

Presentation

A portable preterm imaging system: clinical study

Tananant Boonya-Ananta, Jessica Ramella-Roman

Proceedings Volume PC12382, PC1238206 (2023) https://doi.org/10.1117/12.2657296

KEYWORDS: Imaging systems, Brain-machine interfaces, Silicon, Point-of-care devices, Optical components, Optical alignment, Neurological disorders, Interfaces, Human subjects, Diagnostics

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Proceedings Article | 15 March 2023 Presentation

Presentation

Cervical collagen and elastic fibers classification with Mueller matrix polarimetry (Conference Presentation)

Ajmal Ajmal, Tananant Boonya-Ananta, Jessica Ramella-Roman

Proceedings Volume PC12382, PC123820B (2023) https://doi.org/10.1117/12.2657297

KEYWORDS: Optical fibers, Collagen, Polarimetry, Cervix, Visualization, Visual optics, Tissues, Tissue optics, Second-harmonic generation, Nonlinear optics

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Proceedings Article | 15 March 2023 Presentation

Presentation

Polarimetric diagnosis of biological tissue: complete versus partial Mueller polarimetry (Conference Presentation)

Tatiana Novikova, Jessica Ramella-Roman

Proceedings Volume PC12382, PC123820J (2023) https://doi.org/10.1117/12.2650634

KEYWORDS: Polarimetry, Tissues, Tissue optics, Biomedical optics, Anisotropy, Wave plates, Medical imaging, Medical diagnostics

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Proceedings Article | 6 March 2023 Presentation

Presentation

Tissue mimicking material selection and finger phantom design for pulse oximetry

Andres Rodriguez, Sandhya Vasudevan, Masoud Farahmand, Sandy Weininger, William Vogt, Christopher Scully, Jessica Ramella-Roman, T. Joshua Pfefer

Proceedings Volume PC12370, PC123700I (2023) https://doi.org/10.1117/12.2657568

KEYWORDS: Oximetry, Tissues, Tissue optics, Blood, 3D printing, Skin, Silicon, Scattering, Optics manufacturing, Optical fabrication

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Proceedings Article | 6 March 2023 Presentation

Presentation

The influence of obesity on the skin's optical properties

Jessica Ramella-Roman, Cristina Palacios, Ajmal Ajmal, Tananant Boonya-Ananta, Andres Rodriguez

Proceedings Volume PC12370, PC123700G (2023) https://doi.org/10.1117/12.2657683

KEYWORDS: Skin, Optical properties, Point-of-care devices, Physiology, Photoplethysmography, Oximetry, Optical components, Medicine, Biomedical optics

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Proceedings Article | 30 May 2022 Presentation

Presentation

Preterm birth risk assessment with imaging Mueller polarimetry: mice model of pregnancy

Hee Ryung Lee, Ilyas Saytashev, Vinh Nguyen Du Le, Mala Mahendroo, Jessica Ramella-Roman, Tatiana Novikova

Proceedings Volume PC12147, PC121470D (2022) https://doi.org/10.1117/12.2622746

KEYWORDS: Polarimetry, Collagen, Mouse models, Optical fibers, Cervix, Statistical analysis, Microscopy, Tissues, Tissue optics, Surgery

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SPIE Journal Paper | 29 March 2022 Open Access

Open Access

Skin optical properties in the obese and their relation to body mass index: a review

Andres Rodriguez, Mel Tananant Boonya-Ananta, Mariacarla Gonzalez, Vinh Nguyen Du Le, Jesse Fine, Cristina Palacios, Mike McShane, Gerard Coté, Jessica Ramella-Roman

JBO, Vol. 27, Issue 03, 030902, (March 2022) https://doi.org/10.1117/12.10.1117/1.JBO.27.3.030902

KEYWORDS: Skin, Collagen, Scattering, Absorption, Tissues, Optical properties, Brain-machine interfaces, Blood, Water, Capillaries

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Significance: Obesity is a worldwide epidemic contributing directly to several cardiovascular risk factors including hypertension and type 2 diabetes. Wearable devices are becoming better at quantifying biomarkers relevant for the management of health and fitness. Unfortunately, both anecdotal evidence and recent studies indicate that some wearables have higher levels of error when utilized by populations with darker skin tones and high body mass index (BMI). There is an urgent need for a better evaluation of the limits of wearable health technologies when used by obese individuals. Aims: (1) To review the current know-how on changes due to obesity in the skin epidermis, dermis, and subcutis that could affect the skin optical properties; (2) for the green wavelength range, to evaluate the difference in absorption and scattering coefficients from the abdominal skin between individuals with and without elevated BMI. The changes include alterations in layer thickness and cell size, as well as significant differences in chromophores and scatterer content, e.g., water, hemoglobin, collagen, and lipids. Approach: We have summarized literature pertaining to changes in skin and its components in obesity and report the results of our search using articles published between years 1971 and 2020. A linear model was used to demonstrate the absorption and reduced scattering coefficient of the abdominal skin of individuals with and without elevated BMI in the green wavelength range (530 to 550 nm) that is typically found in most wearables. Results: The general trends indicate a decrease in absorption for both dermis and subcutis and an increase in reduced scattering for both epidermis and dermis. At 544-nm wavelength, a typical wavelength used for photoplethysmography (PPG), the absorption coefficient’s relative percentage difference between high and low BMI skin, was 49% in the subcutis, 19% in the dermis, and negligible in the epidermis, whereas the reduced scattering coefficient relative difference was 21%, 29%, and 165% respectively. Conclusions: These findings suggest that there could be significant errors in the output of optical devices used for monitoring health and fitness if changes due to obesity are not accounted for in their design.

Proceedings Article | 7 March 2022 Presentation

Presentation

Detection of cervical collagen remodeling with Mueller polarimetry in mice model of pregnancy

Hee Ryung Lee, Ilyas Saytashev, Vinh Nguyen Du Le, Mala Mahendroo, Jessica Ramella-Roman, Tatiana Novikova

Proceedings Volume PC11963, PC1196309 (2022) https://doi.org/10.1117/12.2610083

KEYWORDS: Collagen, Polarimetry, Mouse models, Optical fibers, Cervix, Tissues, Tissue optics, Statistical analysis, Microscopy, Harmonic generation

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Proceedings Article | 7 March 2022 Presentation

Presentation

Award Announcement

Jessica Ramella-Roman

Proceedings Volume PC11963, PC1196301 (2022) https://doi.org/10.1117/12.2632060

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Proceedings Article | 4 March 2022 Paper

Paper

A speculum free portable preterm imaging system

Tananant Boonya-Ananta, Mariacarla Gonzalez, Vinh Nguyen Du Le, Edward DeHoog, Michael Paidas, Arumugam Jayakumar, Jessica Ramella-Roman

Proceedings Volume 11963, 119630A (2022) https://doi.org/10.1117/12.2609915

KEYWORDS: Imaging systems, Cervix, Cameras, Computer aided design, Polarization, Optical components, Polarizers, Optical design, Light emitting diodes, In vivo imaging

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Proceedings Article | 4 March 2022 Paper

Paper

Machine learning powered Mueller matrix microscope for collagen and elastin visualization in the mouse cervix

Mariacarla Gonzalez, Camilo Roa, Arturo Jimenez, Rachelle Gomez-Guevara, V. N. Du Le, Tatiana Novikova, Jessica Ramella-Roman

Proceedings Volume 11963, 119630B (2022) https://doi.org/10.1117/12.2609978

KEYWORDS: Collagen, Digital filtering, Cervix, Visualization, Microscopes, Tissues, Machine learning, Wave plates, Polarization, Polarimetry

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Proceedings Article | 2 March 2022 Presentation + Paper

Presentation + Paper

In-vivo human study of skin optical properties in individuals with obesity

Andres Rodriguez, Michael Alzamora, Ajmal Ajmal, Tananant Boonya-Ananta, Vinh Nguyen Du Le, Ingemar Fredriksson, Tomas Strömberg, Jessica Ramella-Roman

Proceedings Volume 11968, 119680B (2022) https://doi.org/10.1117/12.2610464

KEYWORDS: Optical properties, Skin, Absorption, Scattering, Tissues, Oxygen, Statistical analysis, Optical sensors, In vivo imaging, Data communications

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SPIE Journal Paper | 30 June 2021 Open Access

Open Access

Special Section Guest Editorial: Wearable, Implantable, Mobile, and Remote Biomedical Optics and Photonics

Jessica Ramella-Roman, Amir Gandjbakhche, Stephen Kanick, Babak Shadgan, Bruce Tromberg

JBO, Vol. 26, Issue 06, 062701, (June 2021) https://doi.org/10.1117/12.10.1117/1.JBO.26.6.062701

KEYWORDS: Point-of-care devices, Photonics, Biomedical optics, Tissues, Sensors, Tissue optics, Skin, Speckle, Signal to noise ratio, Optical phantoms

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Proceedings Article | 5 March 2021 Presentation

Presentation

4x3 Mueller matrix imager for cervical health diagnosis

Mariacarla Gonzalez, Jessica Ramella-Roman

Proceedings Volume 11646, 116460H (2021) https://doi.org/10.1117/12.2579261

KEYWORDS: Imaging systems, Polarization, Polarimetry, Sensors, Cervical cancer, Cell biology, Cameras, Biopsy, Biological research

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Proceedings Article | 5 March 2021 Presentation

Presentation

Welcome and Introduction to SPIE Conference 11646

Jessica Ramella-Roman, Hui Ma, Tatiana Novikova

Proceedings Volume 11646, 1164602 (2021) https://doi.org/10.1117/12.2592748

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Proceedings Article | 5 March 2021 Presentation

Presentation

Investigation of optical heart rate sensors in wearables and the influence of skin tone and obesity on photoplethysmography (PPG) signal

Ajmal Ajmal, Tananant Boonya-Ananta, Andres Rodriguez, Vinh Nguyen Du Le, Jessica Ramella-Roman

Proceedings Volume 11638, 1163808 (2021) https://doi.org/10.1117/12.2578023

KEYWORDS: Sensors, Heart, Photoplethysmography, Blood, Tissue optics, Skin, Measurement devices, Finite element methods, Monte Carlo methods

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Proceedings Article | 5 March 2021 Presentation

Presentation

Synthetic photoplethysmographic waveform at the radial artery

Tananant Boonya-Ananta, Andres Rodriguez, Ajmal Ajmal, Du Le, Joshua Hutcheson, Jessica Ramella-Roman

Proceedings Volume 11640, 116400O (2021) https://doi.org/10.1117/12.2578951

KEYWORDS: Arteries, Photoplethysmography, Blood pressure, Tissue optics, Signal attenuation, Monte Carlo methods, Instrument modeling, Geometrical optics, Finite element methods, Blood

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Proceedings Article | 5 March 2021 Presentation

Presentation

Auto-detection of cervical collagen and elastin in Mueller Matrix polarimetry microscopic images using K-NN and Semantic Segmentation classification

Camilo Roa, Vinh Nguyen Du Le, Jessica Ramella-Roman

Proceedings Volume 11646, 116460Z (2021) https://doi.org/10.1117/12.2578997

KEYWORDS: Tissues, Collagen, Polarimetry, Databases, Cervix, Transform theory, Statistical analysis, Polarization, Mueller matrices, Microscopy

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SPIE Journal Paper | 15 November 2020 Open Access

Open Access

Design and implementation of a portable colposcope Mueller matrix polarimeter

Mariacarla Gonzalez, Karla Alejandra Montejo, Karl Krupp, Vijaya Srinivas, Edward DeHoog, Purnima Madhivanan, Jessica Ramella-Roman

JBO, Vol. 25, Issue 11, 116006, (November 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.11.116006

KEYWORDS: Polarimetry, Polarization, Cervix, Collagen, Cervical cancer, Light emitting diodes, Imaging systems, Image filtering, Silicon, Cameras

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Proceedings Article | 2 April 2020 Open Access

Open Access

Presentation

Post-processing of multimodal microscopic images of tissue histological cuts for biomedical diagnostic (Conference Presentation)

Tatiana Novikova, Hee Ryung Lee, Ilyas Saytashev, Christian Lotz, Florian Kai Groeber-Becker, Sofia Dembski, Razvigor Ossikovski, Jessica Ramella-Roman

Proceedings Volume 11363, 113630D (2020) https://doi.org/10.1117/12.2556880

KEYWORDS: Tissues, Image segmentation, Diagnostics, Tissue optics, Microscopy, Biomedical optics, Polarimetry, Cancer, Second-harmonic generation, Collagen

Read Abstract +

Histological analysis with white light microscopy of few micron-thick sections of tissue remains a gold standard for tissue biopsy. However, this approach requires a cumbersome multi-step preparation of the sample and relies heavily on the skills of a pathologist. In general, any tissue pathology (e.g. inflammation, fibrosis, cancer) affects the constituents of tissue and changes both optical properties of cells and extracellular matrix. We suggest using the images of transmittance, retardance and depolarization of unstained tissue samples, acquired with the Mueller microscopy, as an input data for automated diagnostic image segmentation. The potential of combining polarimetric data with non-linear microscopy data, such as Second Harmonic Generation (SHG) and Two Photon Emission Fluorescence (TPEF), is also explored for the diagnostic of tissue specific components (e. g. collagen, elastin). The unstained histological cuts of full thickness skin equivalents and cervical tissue of mouse were used for multi-modal microscopy imaging. First, the statistical approach was tested for a segmentation of the images of artificial skin using the images of retardance, depolarization, and transmitted unpolarized intensity. The algorithm of density-based spatial clustering of applications with noise (DBSCAN) clearly discriminates the regions of dermal and epidermal layers of skin cuts. The same approach was tested on the extended set of data including polarimetric, SHG and TPEF images of the histological cuts of mouse uterine cervix. The typical circumferential arrangement of collagen fibers around the cervical os as well as elastin lining of the internal cavities was observed on the segmented images. Merging polarimetric data with SHG data makes clear the appearance of fine structures in the cervical os region. The work is ongoing on testing different data post-processing algorithms for increasing both contrast and accuracy of tissue image segmentation, thus, paving the way for the digital histology for tissue diagnostic.

Proceedings Article | 9 March 2020 Presentation

Presentation

Design of wearable devices for diverse populations (Conference Presentation)

Jessica Ramella-Roman

Proceedings Volume 11230, 112300O (2020) https://doi.org/10.1117/12.2550356

KEYWORDS: Tissue optics, Skin, Heart, Blood pressure, Glucose, Monte Carlo methods, Instrument modeling

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Proceedings Article | 20 February 2020 Presentation + Paper

Presentation + Paper

Modeling of a photoplethysmographic (PPG) waveform through monte carlo as a method of deriving blood pressure in individuals with obesity.

Tananant Boonya-ananta, Andres Rodriguez, Anders Hansen, Joshua Hutcheson, Jessica Ramella-Roman

Proceedings Volume 11238, 112380A (2020) https://doi.org/10.1117/12.2546589

KEYWORDS: Monte Carlo methods, Arteries, Blood pressure, Wave propagation, Photoplethysmography, Optical properties, Reflectivity, Tissue optics, Blood, Finite element methods

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Proceedings Article | 20 February 2020 Presentation + Paper

Presentation + Paper

Experimental integration of a spatial frequency domain spectroscopy and pulse cam system for quantifying changes in skin optical properties and vasculature among individuals with obesity

Andres Rodriguez, Tananant Boonya-ananta, Akash Kumar Maity, Ashok Veeraraghavan, Rolf Saager, Jessica Ramella-Roman

Proceedings Volume 11211, 1121105 (2020) https://doi.org/10.1117/12.2546642

KEYWORDS: Skin, Optical properties, Tissue optics, Spectroscopy, Digital Light Processing, Cameras, Imaging systems, Blood, Tissues, Brain-machine interfaces

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Proceedings Article | 14 February 2020 Presentation + Paper

Presentation + Paper

Parallelized multi-layered Monte Carlo model for evaluation of a proximal phalanx photoplethysmograph

Jesse Fine, Tananant Boonya-ananta, Andres Rodriguez, Jessica Ramella-Roman, Mike McShane, Gerard Cote

Proceedings Volume 11247, 1124702 (2020) https://doi.org/10.1117/12.2543590

KEYWORDS: Arteries, Skin, Monte Carlo methods, Blood pressure, Tissues, Tissue optics, Photoplethysmography, Optical properties, Photon transport

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SPIE Journal Paper | 8 March 2019 Open Access

Open Access

Optical phantoms for biomedical polarimetry: a review

Joseph Chue-Sang, Mariacarla Gonzalez, Angie Pierre, Megan Laughrey, Ilyas Saytashev, Tatiana Novikova, Jessica C. Ramella-Roman

JBO, Vol. 24, Issue 03, 030901, (March 2019) https://doi.org/10.1117/12.10.1117/1.JBO.24.3.030901

KEYWORDS: Polarimetry, Tissues, Polarization, Birefringence, Biomedical optics, Optical phantoms, Tissue optics, Collagen, Scattering, Polymers

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Calibration, quantification, and standardization of the polarimetric instrumentation, as well as interpretation and understanding of the obtained data, require the development and use of well-calibrated phantoms and standards. We reviewed the status of tissue phantoms for a variety of applications in polarimetry; more than 500 papers are considered. We divided the phantoms into five groups according to their origin (biological/nonbiological) and fundamental polarimetric properties of retardation, depolarization, and diattenuation. We found that, while biological media are generally depolarizing, retarding, and diattenuating, only one of all the phantoms reviewed incorporated all these properties, and few considered at least combined retardation and depolarization. Samples derived from biological tissue, such as tendon and muscle, remain extremely popular to quickly ascertain a polarimetric system, but do not provide quantifiable results aside from relative direction of their principal optical axis. Microspheres suspensions are the most utilized phantoms for depolarization, and combined with theoretical models can offer true quantification of depolarization or degree of polarization. There is a real paucity of birefringent phantoms despite the retardance being one of the most interesting parameters measurable with polarization techniques. Therefore, future work should be directed at generating truly reliable and repeatable phantoms for this metric determination. Diattenuating phantoms are rare and application-specific. Given that diattenuation is considered to be low in most biological tissues, the lack of such phantoms is seen as less problematic. The heterogeneity of the phantoms reviewed points to a critical need for standardization in this field. Ultimately, all research groups involved in polarimetric studies and instruments development would benefit from sharing a limited set of standardized polarimetric phantoms, as is done earlier in the round robin investigations in ellipsometry.

Proceedings Article | 4 March 2019 Presentation

Presentation

Polarized light Monte Carlo simulation of cervical collagen ultrastructure (Conference Presentation)

Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 10876, 108760P (2019) https://doi.org/10.1117/12.2508611

KEYWORDS: Collagen, Monte Carlo methods, Cervix, Polarimetry, Polarized microscopy, Microscopy, In vivo imaging, Signal attenuation, Light scattering, Scattering

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Proceedings Article | 4 March 2019 Presentation

Presentation

NIRS measurements of muscle oximetry in the obese (Conference Presentation)

Andres Rodriguez, Tananant Boonya-ananta, Alex Garrido, Jacob Lopez, Jessica Ramella-Roman

Proceedings Volume 10877, 108770M (2019) https://doi.org/10.1117/12.2508612

KEYWORDS: Near infrared spectroscopy, Oximetry, Mode conditioning cables, Pathophysiology, Proteins, Pathology, Lead, Monte Carlo methods, Light, Oximeters

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Proceedings Article | 4 March 2019 Presentation

Presentation

Voxilization-based Monte Carlo simulation of the ischial tuberosity (Conference Presentation)

Tananant Boonya-ananta, Jessica Ramella-Roman

Proceedings Volume 10877, 108770I (2019) https://doi.org/10.1117/12.2510250

KEYWORDS: Monte Carlo methods, 3D modeling, Skin, Spinal cord, Injuries, SolidWorks, Tissues

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Proceedings Article | 4 March 2019 Presentation

Presentation

Non-invasive determination of retinal temperature through stimulated laser speckle imaging (sLSI) (Conference Presentation)

Sean Kirkpatrick, Nicolle Sevilla, Ilyas Saytashev, Jessica Ramella-Roman

Proceedings Volume 10880, 108800I (2019) https://doi.org/10.1117/12.2509841

KEYWORDS: Laser speckle imaging, Retina, Temperature metrology, Imaging systems, Laser systems engineering, Speckle, Environmental monitoring, Laser therapeutics, Thermography, Laser scanners

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SPIE Journal Paper | 21 December 2018 Open Access

Open Access

Special Section Guest Editorial: Pioneer in Biomedical Optics: Introduction to the Special Section in Honor of Steven L. Jacques

Andreas Hielscher, Jessica Ramella-Roman, Lihong Wang

JBO, Vol. 23, Issue 12, 121601, (December 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.12.121601

KEYWORDS: Biomedical optics, Tissue optics, Tissues, Monte Carlo methods, Biomedical engineering, Skin, Biology, Optical properties, Laser tissue interaction, Cancer

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SPIE Journal Paper | 7 August 2018 Open Access

Open Access

Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropy

Joseph Chue-Sang, Nola Holness, Mariacarla Gonzalez, Joan Greaves, Ilyas Saytashev, Susan Stoff, Amir Gandjbakhche, Viktor Chernomordik, Gene Burkett, Jessica Ramella-Roman

JBO, Vol. 23, Issue 12, 121605, (August 2018) https://doi.org/10.1117/12.10.1117/1.JBO.23.12.121605

KEYWORDS: Cervix, Collagen, Anisotropy, In vivo imaging, Polarimetry, Polarization, Wave plates, Statistical analysis, Diagnostics, Birefringence

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Proceedings Article | 5 April 2018 Presentation

Presentation

Determination of cervical cancer risk with a snapshot Mueller matrix polarimeter in Mysore India (Conference Presentation)

Jessica Ramella-Roman, Mariacarla Gonzalez, Karla Montejo, Karl Krupp, A. DeHoog, Vijaya Srinivas, Purnima Madhivanan

Proceedings Volume 10485, 1048512 (2018) https://doi.org/10.1117/12.2290632

KEYWORDS: Cervical cancer, Polarimetry, Collagen, Medicine, Brain-machine interfaces, Cancer, Gold, Imaging systems

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Proceedings Article | 5 April 2018 Presentation + Paper

Presentation + Paper

Development and characterization of a snapshot Mueller matrix polarimeter for the determination of cervical cancer risk in the low resource setting

Jessica Ramella-Roman, Mariacarla Gonzalez, Joseph Chue-Sang , Karla Montejo, Karl Krup, Vijaya Srinivas, Edward DeHoog, Purnima Madhivanan

Proceedings Volume 10485, 104850X (2018) https://doi.org/10.1117/12.2290592

KEYWORDS: Polarimetry, Cervical cancer, Cervix, Collagen, Polarization, Light emitting diodes, Imaging systems, Diagnostics, Brain-machine interfaces, Optical coherence tomography

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Proceedings Article | 14 March 2018 Presentation

Presentation

Comparison of collagen orientation and distribution in-vivo between non-pregnant and pregnant human cervix using Mueller Matrix polarimetry (Conference Presentation)

Joseph Chue-Sang, Mariacarla Gonzalez, Nola Holness, Ilyas Saytashev, Amir Gandjbakhche, Victor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 10472, 1047205 (2018) https://doi.org/10.1117/12.2290595

KEYWORDS: Collagen, In vivo imaging, Cervix, Polarimetry, Ranging, Polarization, Optical testing, Anisotropy, Stars

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Proceedings Article | 2 March 2018 Presentation + Paper

Presentation + Paper

Optimization of the incident wavelength in Mueller matrix imaging of cervical collagen

Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 10478, 1047809 (2018) https://doi.org/10.1117/12.2290766

KEYWORDS: Collagen, Cervix, Polarimetry, Wave plates, Polymers, Linear polarizers, Anisotropy, Tissues, Scattering, Imaging systems

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Proceedings Article | 22 February 2018 Paper

Paper

Multiphoton microscopy of ECM proteins in baboon aortic leaflet

Mariacarla Gonzalez, Ilyas Saytashev, Camila Luna, Brittany Gonzalez, Alejandro Pinero, Manuel Perez, Sharan Ramaswamy, Jessica Ramella-Roman

Proceedings Volume 10471, 104710Y (2018) https://doi.org/10.1117/12.2291024

KEYWORDS: Collagen, Heart, Proteins, Second-harmonic generation, Multiphoton microscopy, Tissues, Imaging systems, Microscopy, Harmonic generation

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SPIE Journal Paper | 26 October 2017 Open Access

Open Access

Use of combined polarization-sensitive optical coherence tomography and Mueller matrix imaging for the polarimetric characterization of excised biological tissue (Erratum)

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, David Straton, Sharan Ramaswamy, Jessica Ramella-Romana

JBO, Vol. 22, Issue 10, 109801, (October 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.10.109801

KEYWORDS: Polarimetry, Optical coherence tomography, Tissue optics, Biomedical engineering, Medicine

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SPIE Journal Paper | 29 August 2017 Open Access

Open Access

Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, Mariacarla Gonzalez, Nola Holness, Jefferson Gomes, Ranu Jung, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

JBO, Vol. 22, Issue 08, 086010, (August 2017) https://doi.org/10.1117/12.10.1117/1.JBO.22.8.086010

KEYWORDS: Collagen, Cervix, Optical coherence tomography, Polarimetry, Anisotropy, Silicon, Tissues, Optical fibers, Polarization, Uterus

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Proceedings Article | 19 April 2017 Presentation

Presentation

Handheld SFDI/polarimetric imaging device for objective evaluation of hypertrophic scars (Conference Presentation)

Jessica Ramella-Roman, Karla Montejo, Nicole Sevilla, Susan Stoff, Mariacarla Gonzalez, Joseph Chue-Sang

Proceedings Volume 10049, 1004905 (2017) https://doi.org/10.1117/12.2251001

KEYWORDS: Polarimetry, Light emitting diodes, Tissues, Imaging devices, Diagnostics, Imaging systems, Fiber optic illuminators, System integration, Collagen, Surgery

Read Abstract +

Proceedings Article | 2 March 2017 Paper

Paper

Use of Mueller matrix polarimetry and optical coherence tomography in the characterization of cervical collagen anisotropy

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, Mariacarla Gonzalez, Jefferson Gomes, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 10043, 100430U (2017) https://doi.org/10.1117/12.2250969

KEYWORDS: Collagen, Polarimetry, Cervix, Second-harmonic generation, Polarization, Anisotropy, Optical coherence tomography, Silicon, Tissues, Birefringence

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Proceedings Article | 2 March 2017 Presentation + Paper

Presentation + Paper

Use of Mueller matrix colposcopy in the characterization of cervical collagen anisotropy

Karla Montejo, Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, Nola Holness, Mariacarla Gonzalez, Jefferson Gomes, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 10043, 1004303 (2017) https://doi.org/10.1117/12.2250987

KEYWORDS: Collagen, Polarimetry, In vivo imaging, Cervix, Anisotropy, Polarization, Optical coherence tomography, Biomedical optics, Tissue optics, Tissues

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Proceedings Article | 2 March 2017 Paper

Paper

Quantitative analysis of a scar's pliability, perfusion and metrology

Mariacarla Gonzalez, Nicole Sevilla, Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 10067, 100670R (2017) https://doi.org/10.1117/12.2252676

KEYWORDS: Skin, Metrology, Quantitative analysis, Tissues, Visualization, Diagnostics, Laser speckle imaging, Speckle, Injuries, Speckle pattern

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SPIE Journal Paper | 13 July 2016 Open Access

Open Access

Special Section Guest Editorial:Polarized Light for Biomedical Applications

Tatiana Novikova, Igor Meglinski, Jessica Ramella-Roman, Valery Tuchin

JBO, Vol. 21, Issue 07, 071001, (July 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.7.071001

KEYWORDS: Tissue optics, Biomedical optics, Polarimetry, Polarization, Tissues, Light scattering, Diagnostics, Medical research, Cancer, Eye models

Proceedings Article | 27 April 2016 Presentation

Presentation

Imaging of skin surface architecture with out of plane polarimetry (Conference Presentation)

Joseph Chue-Sang, Jessica Ramella-Roman

Proceedings Volume 9689, 96890C (2016) https://doi.org/10.1117/12.2213365

KEYWORDS: Skin, Polarimetry, Imaging systems, Natural surfaces, Light sources, Tissue optics, Polarization, Diagnostics, Current controlled current source

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Proceedings Article | 27 April 2016 Presentation

Presentation

Polarized light in birefringent samples (Conference Presentation)

Joseph Chue-Sang, Yuqiang Bai, Jessica Ramella-Roman

Proceedings Volume 9689, 96890A (2016) https://doi.org/10.1117/12.2213335

KEYWORDS: Tissue optics, Monte Carlo methods, Tissues, Polarization, Collagen, Cervix, Connective tissue, Diseases and disorders, Sensors, Birefringence

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Proceedings Article | 26 April 2016 Presentation

Presentation

Imaging and modeling of collagen architecture in living tissue with polarized light transfer (Conference Presentation)

Jessica Ramella-Roman, Susan Stoff, Joseph Chue-Sang, Yuqiang Bai

Proceedings Volume 9696, 969603 (2016) https://doi.org/10.1117/12.2213222

KEYWORDS: Collagen, Tissue optics, Connective tissue, Diagnostics, Cervical cancer, Skin cancer, Cervix, Imaging systems, Microscopy, Animal model studies

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Proceedings Article | 8 March 2016 Paper

Paper

Cervical collagen imaging for determining preterm labor risks using a colposcope with full Mueller matrix capability

Susan Stoff, Joseph Chue-Sang, Nola Holness, Amir Gandjbakhche, Viktor Chernomordik, Jessica Ramella-Roman

Proceedings Volume 9689, 968947 (2016) https://doi.org/10.1117/12.2213387

KEYWORDS: Fetus, Collagen, Polarimetry, Cervix, Analytical research, Polarization, Diagnostics, Birefringence, Reproductive system, Imaging systems, Standards development

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SPIE Journal Paper | 1 March 2016 Open Access

Open Access

Use of combined polarization-sensitive optical coherence tomography and Mueller matrix imaging for the polarimetric characterization of excised biological tissue

Joseph Chue-Sang, Yuqiang Bai, Susan Stoff, David Straton, Sharan Ramaswamy, Jessica Ramella-Roman

JBO, Vol. 21, Issue 07, 071109, (March 2016) https://doi.org/10.1117/12.10.1117/1.JBO.21.7.071109

KEYWORDS: Optical coherence tomography, Polarimetry, Birefringence, Tissue optics, Tissues, Polarization, Collagen, Imaging systems, Data modeling, Heart

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SPIE Journal Paper | 10 December 2015 Open Access

Open Access

Rapid prototyping of biomimetic vascular phantoms for hyperspectral reflectance imaging

Pejhman Ghassemi, Jianting Wang, Anthony Melchiorri, Jessica Ramella-Roman, Scott Mathews, James Coburn, Brian Sorg, Yu Chen, T. Joshua Pfefer

JBO, Vol. 20, Issue 12, 121312, (December 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.12.121312

KEYWORDS: Printing, 3D printing, Reflectivity, Biomimetics, Tissues, Yeast, Rapid manufacturing, 3D image processing, Hyperspectral imaging, Chromophores

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Proceedings Article | 6 March 2015 Paper

Paper

3D printed biomimetic vascular phantoms for assessment of hyperspectral imaging systems

Jianting Wang, Pejhman Ghassemi, Anthony Melchiorri, Jessica Ramella-Roman, Scott Mathews, James Coburn, Brian Sorg, Yu Chen, Joshua Pfefer

Proceedings Volume 9325, 932508 (2015) https://doi.org/10.1117/12.2084720

KEYWORDS: 3D printing, Imaging systems, 3D image processing, Reflectivity, Printing, Yeast, Hyperspectral imaging, Image segmentation, Tissues, Oximetry

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Proceedings Article | 5 March 2015 Paper

Paper

The role of camera and illumination choices in absolute blood velocity measurements

Jessica Ramella-Roman, S. Winhoven

Proceedings Volume 9322, 93220S (2015) https://doi.org/10.1117/12.2081340

KEYWORDS: Cameras, Blood, Retina, Velocity measurements, Capillaries, Imaging systems, Blood circulation, Radon transform, Doppler effect, Error analysis

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Proceedings Article | 26 February 2015 Paper

Paper

Preferential alignment of birefringent tissue measured with polarization sensitive techniques

J. Ramella-Roman, T. Ruiz, P. Ghassemi, T. Travis, J. Shupp, J. Chue-Sang, Y. Bai

Proceedings Volume 9303, 93030I (2015) https://doi.org/10.1117/12.2081338

KEYWORDS: Collagen, Imaging systems, Skin, Biopsy, Biological research, Tissues, Polarization, Polarimetry, Injuries, Anisotropy

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Proceedings Article | 10 March 2014 Paper

Paper

Quantitative assessment of biophotonic imaging system performance with phantoms fabricated by rapid prototyping

Jianting Wang, James Coburn, Nicholas Woolsey, Chia-Pin Liang, Jessica Ramella-Roman, Yu Chen, Joshua Pfefer

Proceedings Volume 8936, 89360M (2014) https://doi.org/10.1117/12.2044089

KEYWORDS: Printing, 3D printing, Optical coherence tomography, Imaging systems, Biomedical optics, Scattering, Reflectivity, Optical properties, Absorption, Rapid manufacturing

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Proceedings Article | 4 March 2014 Paper

Paper

Monitoring the influence of compression therapy on pathophysiology and structure of a swine scar model using multispectral imaging system

Pejhman Ghassemi, Taryn Travis, Jeffrey Shuppa, Lauren Moffatt, Jessica Ramella-Romana

Proceedings Volume 8926, 892606 (2014) https://doi.org/10.1117/12.2037373

KEYWORDS: Imaging systems, Multispectral imaging, Tissues, Avalanche photodetectors, Blood, Skin, Pathophysiology, Actuators, Collagen, Optical properties

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Proceedings Article | 3 March 2014 Paper

Paper

Construction of a digital and physical mouse model aimed at the study of electrical shock

Thu T. Nguyen, Jeffrey Shupp, Lauren Moffatt, Jessica Ramella-Roman

Proceedings Volume 8945, 894508 (2014) https://doi.org/10.1117/12.2039661

KEYWORDS: Tissues, Skin, Temperature metrology, Blood, 3D modeling, Animal model studies, Injuries, Finite element methods, Thermal modeling, Blood circulation

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Proceedings Article | 26 February 2014 Paper

Paper

The efficacy of pressure relief maneuvers in spinal cord injury patients, a clinical study

Thuan Ho, Ahn Thu Nguyen, Alison Lichy, Suzanne Groah, Jessica Ramella-Roman

Proceedings Volume 8938, 89380U (2014) https://doi.org/10.1117/12.2039545

KEYWORDS: Spinal cord, Injuries, Skin, Fiber optics, Sensors, Fiber lasers, Tissues, Fiber optics tests, Clinical trials, Ischemia

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Proceedings Article | 31 May 2013 Paper

Paper

Characterization and application of 3D-printed phantoms for biophotonic imaging

Jianting Wang, James Coburn, Chia-Pin Liang, Nicholas Woolsey, Du Le, Jessica Ramella-Roman, Yu Chen, Joshua Pfefer

Proceedings Volume 8719, 87190Y (2013) https://doi.org/10.1117/12.2018285

KEYWORDS: Absorption, Reflectivity, 3D printing, Biomedical optics, Printing, Optical coherence tomography, Tissues, Optical properties, Scattering, Hyperspectral imaging

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Proceedings Article | 20 March 2013 Paper

Paper

Monitoring the impact of pressure on the assessment of skin perfusion and oxygenation using a novel pressure device

Jessica Ramella-Roman, Thuan Ho, Du Le, Pejhman Ghassemi, Thu Nguyen, Alison Lichy, Suzanne Groah

Proceedings Volume 8576, 85760N (2013) https://doi.org/10.1117/12.2006256

KEYWORDS: Skin, Actuators, Tissue optics, Aluminum, Reflectivity, Sensors, Fiber optics, Doppler effect, Ocean optics, Spinal cord

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Proceedings Article | 20 March 2013 Paper

Paper

Quantitative transverse flow assessment using OCT speckle decorrelation analysis

Xuan Liu, Yong Huang, Jessica Ramella-Roman, Jin Kang

Proceedings Volume 8571, 85712F (2013) https://doi.org/10.1117/12.2006920

KEYWORDS: Optical coherence tomography, Speckle, Blood circulation, Microfluidic imaging, Microfluidics, Blood vessels, Blood, In vivo imaging, Speckle analysis, Biological research

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Proceedings Article | 13 March 2013 Paper

Paper

Spectral variations in narrow band imaging depth-selectivity: mucosal scattering vs. hemoglobin absorption

Quanzeng Wang, Du Le, Jessica Ramella-Roman, Joshua Pfefer

Proceedings Volume 8573, 85730N (2013) https://doi.org/10.1117/12.2008768

KEYWORDS: Scattering, Absorption, Tissues, Reflectivity, Capillaries, Visualization, Blood, Blood vessels, Light scattering, Monte Carlo methods

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Proceedings Article | 8 March 2013 Paper

Paper

A novel spectral imaging system for quantitative analysis of hypertrophic scar

Pejhman Ghassemi, Jeffrey Shupp, Lauren Moffatt, Jessica Ramella-Roman

Proceedings Volume 8565, 85650U (2013) https://doi.org/10.1117/12.2006096

KEYWORDS: Imaging systems, Polarization, Collagen, Polarimetry, Polarizers, Birefringence, Imaging spectroscopy, Scattering, Gold, Optical properties

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Proceedings Article | 15 February 2013 Paper

Paper

Skin microvascular and metabolic response to pressure relief maneuvers in people with spinal cord injury

Jessica Ramella-Roman, Du Le, Pejhman Ghassemi, Thu Nguyen, Alison Lichy, Suzanne Groah

Proceedings Volume 8579, 85790R (2013) https://doi.org/10.1117/12.2006260

KEYWORDS: Skin, Injuries, Tissues, Ocean optics, Spinal cord, Doppler effect, Sensors, Fiber optics, Laser spectroscopy, Fiber lasers

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SPIE Journal Paper | 13 December 2012 Open Access

Open Access

Monte Carlo modeling of light-tissue interactions in narrow band imaging

Du Le, Quanzeng Wang, Jessica Ramella-Roman, T. Joshua Pfefer

JBO, Vol. 18, Issue 01, 010504, (December 2012) https://doi.org/10.1117/12.10.1117/1.JBO.18.1.010504

KEYWORDS: Absorption, Monte Carlo methods, Scattering, Tissue optics, Tissues, Optical properties, Capillaries, Reflectivity, Instrument modeling, Blood vessels

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SPIE Journal Paper | 9 July 2012 Open Access

Open Access

Out-of-plane Stokes imaging polarimeter for early skin cancer diagnosis

Pejhman Ghassemi, Paul Lemaillet, Jessica Ramella-Roman, Jeffrey Shupp, Suraj Venna, Marc Boisvert, Katherine Flanagan, Marion Jordan, Thomas Germer

JBO, Vol. 17, Issue 7, 076014, (July 2012) https://doi.org/10.1117/12.10.1117/1.JBO.17.7.076014

KEYWORDS: Polarization, Scattering, Skin, Polarimetry, Light scattering, Melanoma, Skin cancer, Calibration, Imaging systems, Polarizers

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Proceedings Article | 16 May 2012 Paper

Paper

Development and testing of a fluorescence biosensor for glucose sensing

Mamdouh Aloraefy, Joshua Pfefer, Jessica Ramella-Roman, Kim Sapsford

Proceedings Volume 8367, 83670H (2012) https://doi.org/10.1117/12.920699

KEYWORDS: Glucose, Luminescence, Biosensors, Sensors, Fluorescence resonance energy transfer, Receptors, Polymers, Biosensing, Molecules, Calibration

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Proceedings Article | 16 May 2012 Paper

Paper

Fabrication of microfluidic vascular phantoms by laser micromachining

Scott Mathews, Long Luu, Jessica Ramella-Roman

Proceedings Volume 8367, 83670B (2012) https://doi.org/10.1117/12.920805

KEYWORDS: Microfluidics, Micromachining, Blood circulation, Capillaries, Laser systems engineering, Image processing, Fabrication, Interfaces, Scattering, Rapid manufacturing

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Proceedings Article | 16 May 2012 Paper

Paper

Quantitative evaluation of mucosal vascular contrast in narrow band imaging using Monte Carlo modeling

Du Le, Quanzeng Wang, Jessica Ramella-Roman, Joshua Pfefer

Proceedings Volume 8367, 836709 (2012) https://doi.org/10.1117/12.918375

KEYWORDS: Tissues, Absorption, Scattering, Blood, Reflectivity, Monte Carlo methods, Blood vessels, Photons, Visualization, Optical properties

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Proceedings Article | 28 February 2012 Paper

Paper

Visualization of mucosal vasculature with narrow band imaging: a theoretical study

Quanzeng Wang, Du Le, Jessica Ramella-Roman, Joshua Pfefer

Proceedings Volume 8215, 821505 (2012) https://doi.org/10.1117/12.906817

KEYWORDS: Tissues, Absorption, Visualization, Blood vessels, Scattering, Reflectivity, Blood, Photons, Monte Carlo methods, Bandpass filters

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Proceedings Article | 9 February 2012 Paper

Paper

Combination of Stokes polarized light imaging, roughness metrics and morphological features for the detection of melanoma

P. Ghassemi, J. Shupp, S. Venna, M. Boisvert, K. Flanagan, M. Jordan, J. Ramella-Roman

Proceedings Volume 8207, 82070H (2012) https://doi.org/10.1117/12.910534

KEYWORDS: Melanoma, Skin, Polarization, Binary data, Skin cancer, Imaging systems, Image filtering, Polarimetry, Diagnostics, Cancer

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Proceedings Article | 9 February 2012 Paper

Paper

Modeling of skin cooling, blood flow, and optical properties in wounds created by electrical shock

Thu Nguyen, Jeffrey Shupp, Lauren Moffatt, Marion Jordan, James Jeng, Jessica Ramella-Roman

Proceedings Volume 8207, 820706 (2012) https://doi.org/10.1117/12.909594

KEYWORDS: Blood, Skin, Tissues, Blood circulation, Temperature metrology, Finite element methods, Injuries, Optical properties, Blood vessels, Cameras

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Proceedings Article | 12 April 2011 Paper

Paper

Assessment of electrical burn injury using structured illumination in an in-vivo electrical injury model

Thu T. A. Nguyen, Ali Basiri, J. Shupp, L. Moffatt, M. Jordan, J. Jeng, E. Leto, J. Ramella-Roman

Proceedings Volume 7999, 79990D (2011) https://doi.org/10.1117/12.890313

KEYWORDS: Injuries, Optical properties, Skin, Imaging systems, Absorption, Tissues, Scattering, Imaging spectroscopy, Temperature metrology, Tissue optics

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SPIE Journal Paper | 1 April 2011 Open Access

Open Access

Spectroscopic sensitive polarimeter for biomedical applications

Jessica Ramella-Roman, Amritha Nayak, Scott Prahl

JBO, Vol. 16, Issue 04, 047001, (April 2011) https://doi.org/10.1117/12.10.1117/1.3561907

KEYWORDS: Polarimetry, Calibration, Polarizers, Spectroscopy, Polarization, Biomedical optics, Scattering, Rayleigh scattering, Liquid crystals, Wave plates

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Proceedings Article | 22 February 2011 Paper

Paper

Broadband UV-Vis optical property measurement in layered turbid media

Quanzeng Wang, Du Le, Jessica Ramella-Roman, Joshua Pfefer

Proceedings Volume 7891, 78910F (2011) https://doi.org/10.1117/12.879647

KEYWORDS: Reflectivity, Tissues, Data modeling, Absorption, Fiber optics, Scattering, Optical fibers, Optical properties, Monte Carlo methods, Calibration

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Proceedings Article | 18 February 2011 Paper

Paper

Hemispherical Stokes polarimeter for early cancer diagnosis

Paul Lemaillet, Jessica Ramella-Roman

Proceedings Volume 7883, 788304 (2011) https://doi.org/10.1117/12.873608

KEYWORDS: Polarization, Polarimetry, Scattering, Skin, Polarizers, Liquid crystals, Calibration, Imaging systems, Wave plates, Optical properties

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Proceedings Article | 18 February 2011 Paper

Paper

Detection of familial adenomatous polyposis with polarized spectroscopic imaging and oral vascular density

Ali Basiri, Daniel Edelstein, Francis Giardiello, J. Ramella-Roman

Proceedings Volume 7897, 78970P (2011) https://doi.org/10.1117/12.875193

KEYWORDS: Control systems, Reflectivity, Colorectal cancer, Genetics, Laser induced plasma spectroscopy, Error control coding, Imaging spectroscopy, Spectroscopy, Imaging systems, Tissues

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Proceedings Article | 12 February 2011 Paper

Paper

Measuring the retina optical properties using a structured illumination imaging system

A. Basiri, T. Nguyen, M. Ibrahim, Q. Nguyen, Jessica Ramella-Roman

Proceedings Volume 7885, 78851X (2011) https://doi.org/10.1117/12.875146

KEYWORDS: Retina, Optical properties, Imaging systems, Oxygen, Modulation, Monte Carlo methods, Eye, Capillaries, Cameras, Binary data

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SPIE Journal Paper | 1 September 2010 Open Access

Open Access

Absolute blood velocity measured with a modified fundus camera

Donald Duncan, Paul Lemaillet, Mohamed Ibrahim, Quan Dong Nguyen, Matthias Hiller, Jessica Ramella-Roman

JBO, Vol. 15, Issue 05, 056014, (September 2010) https://doi.org/10.1117/12.10.1117/1.3494565

KEYWORDS: Blood, Cameras, Velocity measurements, Error analysis, Signal to noise ratio, Radon transform, In vitro testing, Eye, Image processing, Blood circulation

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Proceedings Article | 3 March 2010 Paper

Paper

Retinal oximetry with a multiaperture camera

Paul Lemaillet, Art Lompado, Mohamed Ibrahim, Quan Dong Nguyen, Jessica Ramella-Roman

Proceedings Volume 7550, 755021 (2010) https://doi.org/10.1117/12.841980

KEYWORDS: Reflectivity, Retina, Oxygen, Calibration, Eye, Cameras, Absorption, Optical filters, Charge-coupled devices, Oximetry

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Proceedings Article | 2 March 2010 Paper

Paper

Imaging spectroscopy of thermal and electrical burs

Thu Ann Nguyen, Ali Basiri, Jessica Ramella-Roman

Proceedings Volume 7548, 75480C (2010) https://doi.org/10.1117/12.842057

KEYWORDS: Skin, Tissues, Electrodes, Injuries, Imaging spectroscopy, Oxygen, Thermography, Cameras, Spectroscopy, Power supplies

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SPIE Journal Paper | 1 November 2009 Open Access

Open Access

Dynamic eye phantom for retinal oximetry measurements

Paul Lemaillet, Jessica Ramella-Roman

JBO, Vol. 14, Issue 06, 064008, (November 2009) https://doi.org/10.1117/12.10.1117/1.3258669

KEYWORDS: Eye, Oxygen, Scattering, Eye models, Optical properties, Reflectivity, Blood, Oximetry, Retina, Absorption

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Proceedings Article | 28 February 2009 Paper

Paper

Improvement of a snapshot spectroscopic retinal multi-aperture imaging camera

Paul Lemaillet, Art Lompado, Jessica Ramella-Roman

Proceedings Volume 7262, 72622G (2009) https://doi.org/10.1117/12.811565

KEYWORDS: Cameras, Lenses, Oxygen, Eye, Charge-coupled devices, Spectroscopy, Imaging spectroscopy, Retina, Optical filters, Retinal scanning

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Proceedings Article | 23 February 2009 Paper

Paper

Quantitative assessment of autonomic dysreflexia with combined spectroscopic and perfusion probes

Jessica Ramella-Roman, Allison Pfefer, Joseph Hidler

Proceedings Volume 7169, 716916 (2009) https://doi.org/10.1117/12.809000

KEYWORDS: Skin, Injuries, Bladder, Nervous system, Sensors, Oxygen, Doppler effect, Blood circulation, Spectroscopy, Reflectivity

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Proceedings Article | 23 February 2009 Paper

Paper

Assessment of skin wound healing with a multi-aperture camera

Marjan Nabili, Alex Libin, Loan Kim, Susan Groah, Jessica Ramella-Roman

Proceedings Volume 7161, 71610S (2009) https://doi.org/10.1117/12.808956

KEYWORDS: Skin, Wound healing, Cameras, Oxygen, Imaging systems, Reflectivity, Polarizers, Optical filters, Digital cameras, Imaging spectroscopy

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Proceedings Article | 21 February 2008 Paper

Paper

Calibration of an eye oximeter with a dynamic eye phantom

A. Nabili, D. Bardakci, K. Helling, C. Matyas, S. Muro, J. Ramella-Roman

Proceedings Volume 6870, 68700N (2008) https://doi.org/10.1117/12.767556

KEYWORDS: Eye, Retina, Blood, Oxygen, Eye models, Optical properties, Scattering, Sclera, Absorption, Monte Carlo methods

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Proceedings Article | 8 February 2008 Paper

Paper

Detection of blood oxygen level by noninvasive passive spectral imaging of skin

Neelam Gupta, Jessica Ramella-Roman

Proceedings Volume 6842, 68420C (2008) https://doi.org/10.1117/12.768708

KEYWORDS: Imaging systems, Polarization, Skin, Crystals, Acoustics, Hyperspectral imaging, Imaging spectroscopy, Liquid crystals, Wave plates, Transducers

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Proceedings Article | 8 February 2008 Paper

Paper

Polarized fluorescence for skin cancer diagnostic with a multi-aperture camera

Haripriya Kandimalla, Jessica Ramella-Roman

Proceedings Volume 6842, 68420J (2008) https://doi.org/10.1117/12.768536

KEYWORDS: Luminescence, Cameras, Polarizers, Skin cancer, Polarization, Optical filters, Tissues, Skin, Imaging systems, Light sources

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Proceedings Article | 5 February 2008 Paper

Paper

A fiber optic probe for measurement of an autonomic dysreflexia event on SCI patients

J. Ramella-Roman, J. Hidler

Proceedings Volume 6852, 685202 (2008) https://doi.org/10.1117/12.768714

KEYWORDS: Skin, Injuries, Oxygen, Fiber optics, Bladder, Blood pressure, Fiber optics tests, Spectrophotometry, Reflectivity, Spinal cord

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Proceedings Article | 13 September 2007 Paper

Paper

Truncated singular value decomposition method for calibrating a Stokes polarimeter

Bruno Boulbry, Jessica Ramella-Roman, Thomas Germer

Proceedings Volume 6682, 66820M (2007) https://doi.org/10.1117/12.734452

KEYWORDS: Polarimetry, Calibration, Polarizers, Polarization, Wave plates, Light emitting diodes, Matrices, Optical components, Refractive index, Liquid crystals

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Proceedings Article | 26 April 2007 Paper

Paper

Hemispherical imaging of skin with polarized light

Jessica Ramella-Roman, Bruno Boulbry, Thomas Germer

Proceedings Volume 6535, 65350U (2007) https://doi.org/10.1117/12.740962

KEYWORDS: Skin, Scattering, Data modeling, Light scattering, Polarization, Glasses, Polarizers, Solids, Diamond, Multiple scattering

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Proceedings Article | 5 March 2007 Paper

Paper

A lenslet-based device for measuring oxygen saturation in the retina

Jessica Ramella-Roman, H. Kandimalla, R. Dinga, A. Nabili, Scott Mathews, Q. Nguyen

Proceedings Volume 6426, 64261J (2007) https://doi.org/10.1117/12.714123

KEYWORDS: Oxygen, Retina, Cameras, Imaging systems, Scattering, Spectroscopy, Blood, Measurement devices, Optical filters, Eye

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Proceedings Article | 25 February 2006 Paper

Paper

A new approach to Mueller matrix reconstruction of skin cancer lesions using a dual rotating retarder polarimeter

Jessica Ramella-Roman, Don Duncan

Proceedings Volume 6080, 60800M (2006) https://doi.org/10.1117/12.646157

KEYWORDS: Wave plates, Polarimetry, Optical components, Polarization, Condition numbers, Mueller matrices, Polarizers, Skin cancer, Chemical elements, Matrices

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Proceedings Article | 22 February 2006 Paper

Paper

A novel hemispherical spectro-polarimetric scattering instrument for skin lesion imaging

Bruno Boulbry, Thomas Germer, Jessica Ramella-Roman

Proceedings Volume 6078, 60780R (2006) https://doi.org/10.1117/12.648164

KEYWORDS: Skin, Polarization, Fiber optic illuminators, Light scattering, Scattering, Imaging systems, Cameras, Tissues, Polarizers, Light emitting diodes

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Proceedings Article | 25 April 2005 Paper

Paper

Out-of-plane polarimetric imaging of skin: surface and subsurface effects

Jessica Ramella-Roman, Donald Duncan, Thomas Germer

Proceedings Volume 5686, (2005) https://doi.org/10.1117/12.592399

KEYWORDS: Skin, Scattering, Light scattering, Cameras, Picosecond phenomena, Gold, Glasses, Polarization, Error analysis, Polarimetry

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SPIE Journal Paper | 1 November 2004 Open Access

Open Access

Design, testing, and clinical studies of a handheld polarized light camera

Jessica Ramella-Roman, Kenneth Lee, Scott Prahl, Steven Jacques

JBO, Vol. 9, Issue 06, (November 2004) https://doi.org/10.1117/12.10.1117/1.1781667

KEYWORDS: Cameras, Polarization, Beam splitters, Skin, Imaging systems, Melanoma, Skin cancer, Prototyping, Objectives, CCD cameras

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Proceedings Article | 8 December 2003 Paper

Paper

Imaging superficial tissue layers using polarized light with a hand-held camera

Steven Jacques, Jessica Ramella-Roman, Kenneth Lee

Proceedings Volume 5254, (2003) https://doi.org/10.1117/12.546083

KEYWORDS: Photons, Cameras, Light scattering, Scattering, Tissue optics, CCD cameras, Polarization, Skin, Data conversion, Melanoma

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Proceedings Article | 14 November 2003 Paper

Paper

A hand-held polarized-light camera for the detection of skin cancer borders

Jessica Ramella-Roman, Kenneth Lee, Steven Jacques

Proceedings Volume 5192, (2003) https://doi.org/10.1117/12.534100

KEYWORDS: Cameras, Skin cancer, Skin, Beam splitters, Polarization, Optical diagnostics, Eye, Cancer, Imaging systems, CCD cameras

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Proceedings Article | 13 October 2003 Paper

Paper

Polarized light imaging with a handheld camera

Jessica Ramella-Roman, Kenneth Lee, Scott Prahl, Steven Jacques

Proceedings Volume 5068, (2003) https://doi.org/10.1117/12.518788

KEYWORDS: Cameras, Polarization, Skin, CCD cameras, Beam splitters, Melanoma, Tissue optics, Image enhancement, Imaging systems, Light sources

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SPIE Journal Paper | 1 July 2002 Open Access

Open Access

Imaging skin pathology with polarized light

Steven Jacques, Jessica Ramella-Roman, Kenneth Lee

JBO, Vol. 7, Issue 03, (July 2002) https://doi.org/10.1117/12.10.1117/1.1484498

KEYWORDS: Skin, Tissues, Cameras, Photons, Light scattering, Pathology, Polarization, Glasses, Natural surfaces, Reflectivity

Proceedings Article | 9 July 2001 Paper

Paper

Mueller-matrix description of collimated light transmission through liver, muscle, and skin

Jessica Ramella-Roman, Steven Jacques

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434693

KEYWORDS: Tissues, Polarization, Skin, Liver, Wave plates, Sensors, Birefringence, Collimation, Mueller matrices, Polarizers

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Proceedings Article | 9 July 2001 Paper

Paper

Characterizing microscopic domains of birefringence in thin tissue sections

Steven Jacques, Alex Moody, Jessica Ramella-Roman

Proceedings Volume 4257, (2001) https://doi.org/10.1117/12.434735

KEYWORDS: Tissues, Skin, Birefringence, Optical testing, Optical fibers, Liver, Polarization, Tissue engineering, Proteins, Microscopes

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Proceedings Article | 13 June 2000 Paper

Paper

Propagation of polarized light beams through biological tissues

Steven Jacques, Jessica Ramella-Roman

Proceedings Volume 3914, (2000) https://doi.org/10.1117/12.388061

KEYWORDS: Tissues, Liver, Skin, Polarization, Light scattering, Optical fibers, Polarizers, Scattering, Statistical analysis, Collagen

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Proceedings Article | 6 April 2000 Paper

Paper

Scattering of polarized light by biological tissues

Steven Jacques, Kenneth Lee, Jessica Ramella-Roman

Proceedings Volume 4001, (2000) https://doi.org/10.1117/12.381506

KEYWORDS: Polarization, Tissues, Light scattering, Skin, Scattering, Cameras, Cancer, Blood, Tissue optics, Reflectivity

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Proceedings Volume Editor (4)

SPIE Conference Volume | 4 April 2024

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024

SPIE Conference Volume | 13 April 2023

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023

SPIE Conference Volume | 31 March 2022

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2022

SPIE Conference Volume | 8 April 2021

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics

Conference Committee Involvement (43)

Optical Diagnostics and Sensing XXV: Toward Point-of-Care Diagnostics

27 January 2025 | San Francisco, California, United States

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2025

25 January 2025 | San Francisco, California, United States

Design and Quality for Biomedical Technologies XVIII

25 January 2025 | San Francisco, California, United States

Optical Diagnostics and Sensing XXIV: Toward Point-of-Care Diagnostics

29 January 2024 | San Francisco, California, United States

Design and Quality for Biomedical Technologies XVII

27 January 2024 | San Francisco, California, United States

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2024

27 January 2024 | San Francisco, California, United States

Optical Diagnostics and Sensing XXIII: Toward Point-of-Care Diagnostics

30 January 2023 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery 2023

28 January 2023 | San Francisco, California, United States

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2023

28 January 2023 | San Francisco, California, United States

Optical Diagnostics and Sensing XXII: Toward Point-of-Care Diagnostics

24 January 2022 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery 2022

22 January 2022 | San Francisco, California, United States

Polarized Light and Optical Angular Momentum for Biomedical Diagnostics 2022

22 January 2022 | San Francisco, California, United States

Polarized light and Optical Angular Momentum for biomedical diagnostics

6 March 2021 | Online Only, California, United States

Photonics in Dermatology and Plastic Surgery 2021

6 March 2021 | Online Only, California, United States

Optical Interactions with Tissue and Cells XXXI

1 February 2020 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery 2020

1 February 2020 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery 2019

2 February 2019 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXX

2 February 2019 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIX

29 January 2018 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery 2018

27 January 2018 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXVIII

30 January 2017 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

28 January 2017 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXVII

14 February 2016 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

13 February 2016 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXVI

8 February 2015 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

7 February 2015 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXV

3 February 2014 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

1 February 2014 | San Francisco, California, United States

Optical Interactions with Tissue and Cells XXIV

5 February 2013 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

2 February 2013 | San Francisco, California, United States

1st International Biophotonics Meeting in Israel

9 December 2012 | Tel Aviv, Israel

Optical Interactions with Tissue and Cells XXIII

23 January 2012 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

21 January 2012 | San Francisco, California, United States

7th NIH Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside

15 September 2011 | Bethesda, Maryland, United States

Optical Interactions with Tissue and Cells XXII

24 January 2011 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

22 January 2011 | San Francisco, California, United States

Optical Interactions with Tissues and Cells XXI

25 January 2010 | San Francisco, California, United States

Photonics in Dermatology and Plastic Surgery

23 January 2010 | San Francisco, California, United States

Inter-Institute Workshop on Optical Diagnostic and Biophotonic Methods from Bench to Bedside

1 October 2009 | Bethesda, Maryland, United States

Optical Interactions with Tissue and Cells XX

26 January 2009 | San Jose, California, United States

Photonics in Dermatology and Plastic Surgery

24 January 2009 | San Jose, California, United States

Optical Interactions with Tissue and Cells XIX

21 January 2008 | San Jose, California, United States

Optical Interactions with Tissue and Cells XVIII

21 January 2007 | San Jose, California, United States

Showing 5 of 43 Conference Committees

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